1.Unusual association of CD8+ T-cell lymphocytosis with invasive thymoma.
Hee Jin HUH ; Jae Woo CHUNG ; Hyun Jung LEE ; Seok Lae CHAE
Blood Research 2015;50(3):184-185
No abstract available.
Lymphocytosis*
;
T-Lymphocytes*
;
Thymoma*
2.Cerebrospinal Fluid Lymphocytosis in Acute Bacterial Meningitis on Children.
Journal of the Korean Pediatric Society 1988;31(6):707-714
No abstract available.
Cerebrospinal Fluid*
;
Child*
;
Humans
;
Lymphocytosis*
;
Meningitis, Bacterial*
3.A Case of Self-Healing Reticulohistiocytosis.
Eun Jung SHIM ; Eun Hye PARK ; Hyun Sang CHO ; Jae Kook CHA ; Eun Sook NAM ; Hae Ran LEE
Korean Journal of Pediatric Hematology-Oncology 2001;8(1):132-136
Self-healing reticulohistiocytosis is a perinatal disease characterized by rapidly developing and involuting benign histiocytic infiltration of the skin and other organ. We had recently experienced a case of a self-healing reticulohistiocytosis in 99-day-old infant who presented with multiple erythematous nodular lesions on face and trunk and pancytopenia. Our case differed from those previously reported in that extracutaneous involvement was found. The patient had pancytopenia, hypertriglyceridemia, hypofibrinogenemia hyperferritinemia and hepatosplenomegaly as well as skin lesions. Bone marrow showed a marked lymphocytosis with many histiocytes. We described a detailed clinical features of this case and reviewed the literatures.
Bone Marrow
;
Histiocytes
;
Humans
;
Hypertriglyceridemia
;
Infant
;
Lymphocytosis
;
Pancytopenia
;
Skin
4.One case of Infectious Mononcleosis.
Kyung Sook CHO ; Do Keum NA ; Byung Gyu KIM ; Sook Hyeon YUN ; Jong Dae JO ; In Sun JEON
Journal of the Korean Pediatric Society 1981;24(9):872-876
A case of infectious mononucleosis was presented. She was admitted to the hospital with the anterior cervical lymphadenopathy. Erythematous skin rashes on both low extermities, and splenomegaly. Her chief complaints were fever and sore throat. She showed atypical lymphocytes in peripheral blood smear with relative lymphocytosis. Mono-spot test was positive. She received symptomatic therapy and discharged without any complications. So, we report this case and review the brief literatures of infectious mononucleosis with the respect to etiology, clinical course, and histological characteristics of the disease.
Exanthema
;
Fever
;
Infectious Mononucleosis
;
Lymphatic Diseases
;
Lymphocytes
;
Lymphocytosis
;
Pharyngitis
;
Splenomegaly
5.A Case of Small Cell Variant of T-Cell Prolymphocytic Leukemia.
Jee Eun PARK ; Kwang Min KIM ; Woo Youl KIM ; Yong Hwan PARK ; Ji Eun OH ; Young Jae KIM ; Kyung Tae PARK
Korean Journal of Hematology 2005;40(3):177-182
T-cell prolymphocytic leukemia (T-PLL) is a post-thymic T-cell malignancy that has an aggressive clinical course and it is a distinct clinico-biological entity from other T-cell disorders. It is now apparent that this disease represents a separate entity from CLL. Clinically, T-PLL presents with hepatosplenomegaly, lymphadenopathy, skin lesion, and marked lymphocytosis exceeding 100x109/L. Because its clinical course is aggressive, the treatment is difficult. We report a case of small cell variant of T-cell with a review of literatures.
Leukemia, Prolymphocytic, T-Cell*
;
Lymphatic Diseases
;
Lymphocytosis
;
Skin
;
T-Lymphocytes*
8.A case of Sulfone syndrome hypersensitivity associated with dapsone.
Hwan Won CHOI ; In Kwan SONG ; Eun A CHUNG ; Dong Youb CHA ; Mi Kyoung LIM ; Dong Jib NA ; Jong Sung CHOI
Journal of Asthma, Allergy and Clinical Immunology 2001;21(6):1206-1210
Sulfone hypersensitivity syndrome, which is characterized by fever, skin rash, hemolytic anemia, atypical lymphocytosis, and acute hepatic injury, is a potentially fatal variant of dapsone hypersensitivity. A 62-year-old woman with a history of arthralgia developed sulfone syndrome while receiving dapsone 100 mg/day for 20 days. Fever, malaise, prominent rashes, hepatitis, eosinophilia and hemolytic anemia developed and she which required hospitalization. The patient's symptoms reversed following discontinuation of dapsone and administration of steroid (0.5 mg/kg). A case of sulfone syndrome and a brief review of the literature were presented.
Anemia, Hemolytic
;
Arthralgia
;
Dapsone*
;
Eosinophilia
;
Exanthema
;
Female
;
Fever
;
Hepatitis
;
Hospitalization
;
Humans
;
Hypersensitivity*
;
Lymphocytosis
;
Middle Aged
9.Three Cases of Allopurinol-induced DRESS Syndrome.
Eun Kyoung JEON ; Kyung Moon LEE ; Yoo Bin KWON ; Young Joon SEO ; Jang Kyu PARK ; Jeung Hoon LEE
Korean Journal of Dermatology 2007;45(7):714-719
Allopurinol (4-hydroxypyrazolo-[3,4-d]pyrimidine) is an effective and widely used xanthine oxidase inhibitor administered in the treatment of hyperuricemic states such as gout. Allopurinol-induced DRESS (Drug rash with eosinophilia and systemic symptoms) syndrome is characterized by hematologic abnormalities, especially eosinophilia and mononucleosis-like atypical lymphocytosis, skin rash, fever, lymph node enlargement and single or multiple organ involvement, which starts within 8 weeks after the initiation of therapy. We report three cases of allopurinol-induced DRESS syndrome who developed erythematous skin eruption six weeks, nine weeks and seven weeks, respectively, after allopurinol therapy. The clinical, laboratory and histologic findings of these patients were compatible with allopurinol-induced DRESS syndrome.
Allopurinol
;
Drug Hypersensitivity Syndrome*
;
Eosinophilia
;
Exanthema
;
Fever
;
Gout
;
Humans
;
Lymph Nodes
;
Lymphocytosis
;
Skin
;
Xanthine Oxidase
10.A Case of Diffuse Infiltrative Lymphocytosis Syndrome Associated with Human Immunodeficiency Virus Infection.
Sun Ok KWON ; Won Wo PARK ; Hyun Kyung LEE ; Sung Soon LEE ; Youn Kyung KANG ; Young Min LEE ; Hyuk Pyo LEE ; Joo In KIM ; Soo Jeon CHOI ; Ho Kee YUM
Tuberculosis and Respiratory Diseases 2006;61(3):289-293
Diffuse infiltrative lymphocytosis syndrome is an autoimmune syndrome that is characterized by the oligoclonal expansion of CD8+ T-lymphocytes in response to human immunodeficiency virus (HIV) antigens. The clinical manifestations include bilateral enlargement of the parotid glands, lymphocytic interstitial pneumonitis, lymphocytic hepatitis, neurological involvement and systemic lymphadenopathies. In addition to a positive HIV test, the diagnostic histopathological findings are CD8+ T-lymphocytic infiltrations in the lymphnodes, liver, lung, muscle and the salivary or lacrimal glands without granulomatous or neoplastic involvement. We report a case of pulmonary involvement of diffuse infiltrative lymphocytosis syndrome that was associated with a human immunodeficiency virus infection.
Hepatitis
;
HIV*
;
Humans*
;
Lacrimal Apparatus
;
Liver
;
Lung
;
Lung Diseases, Interstitial
;
Lymphocytosis*
;
Parotid Gland
;
T-Lymphocytes