No abstract available.
Lymphocytosis* ; T-Lymphocytes* ; Thymoma*

No abstract available.
Cerebrospinal Fluid* ; Child* ; Humans ; Lymphocytosis* ; Meningitis, Bacterial*

A case of infectious mononucleosis was presented. She was admitted to the hospital with the anterior cervical lymphadenopathy. Erythematous skin rashes on both low extermities, and splenomegaly. Her chief complaints were fever and sore throat. She showed atypical lymphocytes in peripheral blood smear with relative lymphocytosis. Mono-spot test was positive. She received symptomatic therapy and discharged without any complications. So, we report this case and review the brief literatures of infectious mononucleosis with the respect to etiology, clinical course, and histological characteristics of the disease.
Exanthema ; Fever ; Infectious Mononucleosis ; Lymphatic Diseases ; Lymphocytes ; Lymphocytosis ; Pharyngitis ; Splenomegaly

Self-healing reticulohistiocytosis is a perinatal disease characterized by rapidly developing and involuting benign histiocytic infiltration of the skin and other organ. We had recently experienced a case of a self-healing reticulohistiocytosis in 99-day-old infant who presented with multiple erythematous nodular lesions on face and trunk and pancytopenia. Our case differed from those previously reported in that extracutaneous involvement was found. The patient had pancytopenia, hypertriglyceridemia, hypofibrinogenemia hyperferritinemia and hepatosplenomegaly as well as skin lesions. Bone marrow showed a marked lymphocytosis with many histiocytes. We described a detailed clinical features of this case and reviewed the literatures.
Bone Marrow ; Histiocytes ; Humans ; Hypertriglyceridemia ; Infant ; Lymphocytosis ; Pancytopenia ; Skin

T-cell prolymphocytic leukemia (T-PLL) is a post-thymic T-cell malignancy that has an aggressive clinical course and it is a distinct clinico-biological entity from other T-cell disorders. It is now apparent that this disease represents a separate entity from CLL. Clinically, T-PLL presents with hepatosplenomegaly, lymphadenopathy, skin lesion, and marked lymphocytosis exceeding 100x109/L. Because its clinical course is aggressive, the treatment is difficult. We report a case of small cell variant of T-cell with a review of literatures.
Leukemia, Prolymphocytic, T-Cell* ; Lymphatic Diseases ; Lymphocytosis ; Skin ; T-Lymphocytes*

Humans ; Infectious Mononucleosis/complications* ; Lymphocytosis ; Lymphohistiocytosis, Hemophagocytic/etiology*

B-Lymphocytes ; Bone Neoplasms ; Humans ; Lumbar Vertebrae ; Lymphocytosis ; Plasmacytoma

Hypersensitivity to mosquito bites is a disorder characterized by necrotic skin reactions and systemic generalized symptoms subsequent to mosquito bites. This disease has been reported mostly in Japanese patients in their first two decades of life. Recent studies have revealed that hypersensitivity to mosquito bites is frequently associated with chronic Epstein-Barr virus infection and natural killer cell leukemia/lymphoma. We describe here a Korean male adolescent who had hypersensitivity to mosquito bites accompanied by chronic Epstein-Barr virus infection and atypical lymphocytosis.
Adolescent ; Asian Continental Ancestry Group ; Culicidae* ; Herpesvirus 4, Human* ; Humans ; Hypersensitivity* ; Killer Cells, Natural ; Lymphocytosis* ; Skin

Allopurinol (4-hydroxypyrazolo-[3,4-d]pyrimidine) is an effective and widely used xanthine oxidase inhibitor administered in the treatment of hyperuricemic states such as gout. Allopurinol-induced DRESS (Drug rash with eosinophilia and systemic symptoms) syndrome is characterized by hematologic abnormalities, especially eosinophilia and mononucleosis-like atypical lymphocytosis, skin rash, fever, lymph node enlargement and single or multiple organ involvement, which starts within 8 weeks after the initiation of therapy. We report three cases of allopurinol-induced DRESS syndrome who developed erythematous skin eruption six weeks, nine weeks and seven weeks, respectively, after allopurinol therapy. The clinical, laboratory and histologic findings of these patients were compatible with allopurinol-induced DRESS syndrome.
Allopurinol ; Drug Hypersensitivity Syndrome* ; Eosinophilia ; Exanthema ; Fever ; Gout ; Humans ; Lymph Nodes ; Lymphocytosis ; Skin ; Xanthine Oxidase

Aged ; B-Lymphocytes ; pathology ; Granulomatosis with Polyangiitis ; diagnosis ; Humans ; Lymphocytosis ; diagnosis ; Male