Objective To understand the risk factors of the elderly in community of Haining city in patients with Alzheimer's disease.Methods Take the elderly Chang street Haining city selected cluster sampling method 7 437 ≥60 years as the research subjects,by using a self-designed questionnaire Alzheimer's disease causes and clinical dementia rating scale,understanding the factors that may affect Alzheimer's disease and aggravating factors,and the data of multi factor regression analysis.Results Multivariate Logistic regression analysis showed that women (Wald x2 =19.96,P ＜ 0.01),aged (Wald x2 =96.01,P ＜ 0.01),widowed (Wald x2 =5.09,P ＜ 0.05),smoking/drinking (Wald x2 =47.77,P ＜ 0.01),living alone (Wald x2 =16.14,P ＜ 0.01),depression (Wald x2 =12.05,P ＜ 0.01) were the risk factors of Alzheimer's disease; Rural (Wald x2 =458.11,P ＜ 0.01) ; Lowculture (Wald x2 =121.39,P ＜0.01) were protective factors for Alzheimer's disease.According to the clinical dementia rating scale of disease severity assessment and pathogenesis of polytomous Logistic regression,the results showed that the elderly (Wald x2 =50.37,P ＜ 0.01),lowculture (Wald x2 =30.39,P ＜ 0.01),widowed (Wald x2 =5.20,P ＜ 0.05),living alone (Wald x2 =16.50,P ＜ 0.01),somatic diseases (Wald x2 =16.58,P ＜ 0.01) and large maternal age (Wald x2 =10.53,P ＜ 0.01) were risk factors for disease.Conclusion Age,widowed,solitude are common risk factors of Alzheimer's disease and aggravating factors,should be combined with risk factors for chronic disease management actively take measures to prevent and delay the occurrence,the development of Alzheimer's disease.