1.Requirement analysis and database design of USIS
Chinese Medical Equipment Journal 1993;0(06):-
Based on the development and application of medical ultrasonic diagnosis information system(USIS) of Nanjing Maternity and Child Health Hospital,this article deeply expounds the requirement analysis and the database design of USIS's development.With the analyses of the distinguishing feature of ultrasonic diagnosis work flow and the design of the relational data structure of USIS,the thought and method to overcome the difficulty of data storage are proposed.
2.Clinical Observation of Oxaliplatin,Mitomycin and Doxorubicin Combined with Three-dimensional Con-formal Radiotherapy for Patients with Lack of Blood Supply Hepatocellular Carcinoma
Luqing CHEN ; Zhiqiang GAO ; Huiyun CHENG ; Zhenyou SUN ; Hongsheng GAO ; Guanghui HE ; Yunzheng ZHAO
China Pharmacy 2017;28(6):749-752
OBJECTIVE:To observe the efficacy and safety of oxaliplatin,mitomycin and doxorubicin combined with three-di-mensional conformal radiotherapy for patients with lack of blood supply hepatocellular carcinoma. METHODS:62 patients with lack of blood supply hepatocellular carcinoma who lose the opportunity of operation were randomly divided into control group(31 cas-es)and observation group(31 cases). Control group received puncture through the femoral artery by Seldiner,selectively interven-ing in hepatic arteries for DSA angiography,then intravenously injected 130 mg/m2 Oxaliplatin for injection via the catheter,once every 2 weeks+Mitomycin for injection 10 mg,intravenously,once every 1-3 week(s)+Doxorubicin for injection 1.2 mg/kg,once every 3 weeks,then giving Iodinated oil emulsifier and Gelatin sponge particle for hepatic artery embolization,appropriate Iodinat-ed oil emulsifier and Gelatin sponge particle once a month,for 3 times. Observation group was additionally received three-dimen-sional conformal radiotherapy 2 Gy,for 25-30 times with total dose of 50-60 Gy,once every 3 days. They were treated for 3-month. Clinical efficacy,the survival rate and median survival time after the first administration of drug for 1,2 and 3 years in 2 groups were observed,and the incidence of adverse reactions was recorded. RESULTS:The total effective rate,the survival rate and median survival time in 1,2 and 3 years in observation were significantly higher than control group,with statistical signifi-cance (P<0.05). The incidences of neutropenia,thrombocytopenia,hemoglobin decreased and radioactive disease in observation group were significantly higher than control group,with statistical significances(P<0.05). CONCLUSIONS:Oxaliplatin,mitomy-cin and doxorubicin combined with three-dimensional conformal radiotherapy have good efficacy for patients with hepatocellular lack of blood supply carcinoma,also can prolong the survival time,they show poor safety.