Objective To know the status of Immunization program in Zhejiang Province.Methods The investigation on immunization program in zhejiang province was conducted,and the SWOT analysis was corducted to make a comprehensive evaluation.Results 11 citys,22 counties and 44 towns were investigated in this study,and the current immunization program in Zhejiang province were explored by SWOT analysis.Conclusion The SWOT Matrix,includes SO(strength-opportunity),ST(strength-threat),WO(weakness-opportunity)and WT(weakness-threat)can apply to make optimal strategy for the development of expanded program on immunization.