After the development and service of information resources in medical library of CDC were described in aspects of its characteristics and service target, the development and service strategies of information resources in medical library of CDC in health information era were analyzed with suggestions put forward for meeting the demands of scientific workers, such as construction of the service platform for sharing digital medical and health literature resources in Hubei Province, development of big data-oriented innovative medical information resources, construction of mobile equipments-based service platform for medical information resources, enforcement of team construction, optimization of staff allocation.