Objective To study the relativity of abnormal cervical pathology results in cytology and histology.Methods With retrospective analysis of 326 cases of fluid-based thin-layer method(ThinPtep cytology test,TCT),which reported in the bethesda system,we checked the abnormal results and advised different diagnose biopsy of vaginoscopy and/or conization and got the relativity description of abnormal results in TCT and CIN Ⅲ/CIS,results validated by vaginoscopy match analysis of the CINⅡ～Ⅲand CINⅢ/CIS results validated by vaginoscopy and conization labeled by the age group and relativity analysis of abnormal results in TCT and CIN Ⅲ/CIS iesuitsvalidated by vaginoscopy.Results 326 cases had confimed biopsy results validated by vaginoscopy,of which 70 cases were of CIN 56 cases were of CIN Ⅲ/CIS,the risk ratio(RR)of different abnonmal TCT results in predicting CINⅢ/CIS resuils validated by vaginoscopy is ASCUS group 14.7(95%confidence interval 8.0～27.0,P=0.00);CINI group 13.9(6.3～30.9,P=0 00);CINⅡgroup 44.2(15.5～126.5,P=0.00);CIN Ⅲ group 272.2(161.6～458.6,P=0.00).Conclusion Vaginoscopy examination and biopsy could verify histology abnormity of CINⅡ～CIN Ⅲ and CIN Ⅲ/CIS from abnormal results of TCT and has a good accordance along with biopsy results of conization.