Objective To investigate the 9 . 4 T of DTT in the diagnosis of SD rat C6 cerebral gliomas model about the change of CST on tumor progression and pathology confirmed. Methods ①10 μl C6 cell suspension of 106 cells number were implanted into the right caudate nucleus of brain hemisphere of 20 adult male SD rat with ster-eotactic technique. ②Application of 9. 4 T of DTT and DTI, meanwhile the routine T1-weighted imaging(T1WI), T2-weighted imaging(T2WI), contrast-enhanced T1WI,FLAIR imaging and diffusion tensor of the brain were ac-quired. Anatomic relationship between cerebral glioma and surrounding white matter fiber tracts was analyzed and measured the values of FA and MD in different areas on fractional anisotropic ( FA) map, color-coded directional map, three-dimensional (3D) white matter fiber tracts map, then stained with routine HE. Results All of SD rat C6 cerebral gliomas models 3 D white matter fiber tracts map by means of FA maps of DTI were successfully comple-ted. Apparently significant differences of FA values were found in solid tumor, surrounding edema, compared with normal white matter regions ( P<0.05 );but there was no significant difference among solid tumor and surrounding edema region (P>0.05);there were significant differences of MD values between solid tumor, surrounding edema and normal white matter region ( P<0.05 ) . Conclusion The 9 . 4 T of DTT offers the optimal visualization of An-atomic relationship between cerebral glioma and surrounding white matter fiber tracts in the different periods of the tumor moder.

Objective To design the meta-data scheme for medical records database of traditional Chinese medi-cine.Methods The meta-data scheme for medical records database of traditional Chinese medicine was designed u-sing the MARC meta-data according to the analysis of resources, investigation of literature, networks and users. Results The meta-data scheme for medical records database of traditional Chinese medicine is consisted of 17 fields and 9 parts.Conclusion MARC, as the mata-data criteria, can organize and describe the medical records of tradi-tional Chinese medicine.However, the standards for selection and description of meta-data criteria need to be fur-ther studied.

Objective To establish the scientific, rational and standard librarian performance appraisal index system in academic library in order to adjust their working behaviors, improve their service quality and increase the overall performance of library.Methods The current librarian performance appraisal situation was investigated according to the literature and on the field inspection.The appraisal indexes and their weight were established by Delphi and step analysis.Results The 3-scale appraisal index system was established, which include 4 No.1 indexes, 10 No. 2 indexes, and 59 No.3 indexes with their weight and score displayed.Conclusion The performance appraisal index system we established can effectively arouse the enthusiasm of librarians in scientific research innovation, manage-ment or social work.

The study of tumors' proteomics is a research hotspot in China and abroad in recent years.The development of theory and technology in proteomics has provided new ideas and research field for cancer research.This paper reviewed the commonly used technical means of proteomics and its research progress on diagnosis,therapy and other aspects of pancreatic carcinoma.

The practicability for local hospitals to take part in bidding for research contracts is re- viewed.Four favorable conditions are pointed out.The administrative process for research contract bid- ding is divided into two aspects:one is the organization and coordination in the course of contract bid- ding;the other is the eight requirements for filling up tenders brought forth from the viewpoint of ad- ministrators.

With the improvement of clinical and scientific research level of pediatric retinal diseases in China,teaching in pediatric retinal diseases for medical students and residents has become increasingly important.Because infants cannot cooperate in ophthalmic examinations,this part becomes a difficult point in clinical teaching and practice.By using the RetCam,a wide-field retinal imaging system,infant's retinal images can display in real time on screen and images and videos can be recorded and reviewed after examination finished.By setting up teaching target reasonably,arranging teaching contents scientifically,and using teaching method properly,we applied multimedia-assisted instruction in teaching pediatric retinal diseases based on RetCam and enhanced teaching effect.

Objective To design and implement the academic impact power information platform for the secondary disciplines of clinical medicine in order to keep abreast of their advantages and disadvantages. Methods An index system for the assessment of secondary disciplines of clinical medicine was constructed with the bibliometric methods according to the factual data. Results Its functions of query analysis, batch input, and editing of the index data of different disciplines were achieved in higher education institutions using the ASP. NET technology based on the data processing, indexing and statistical analysis. Conclusion The platform can provide the data support for the develop-ment and scientific research management of secondary disciplines, and thus playing an important role in promoting the innovative research and management of clinical medicine.

The current situation of subject service and the needs of users for subject service in 4 class A Beijing hospital libraries were investigated with questionnaires. The inadequacies of information service in hospital libraries were summarized and measures for its improvement were put forward.

Objective To analyze academic influence of SCI papers of TCM colleges and universities in the recent 10 years;To provide references for scientific research and academic exchange. Methods According to the evaluation ranking of degree and graduate education development center of Ministry of Education published in 2012 and standardization of InCites database, 10 Chinese medicine colleges and universities were selected. InCites platform was used to select 13 representative indicators and to analyze the cited cases, H index and the cooperation of the SCI papers published in 2006-2015. Results The SCI papers published by 10 TCM colleges and universities have been growing rapidly since 2010, and the average influence of standardized citations was 0.76. The average percentage of cited papers was 67%, which was slightly lower than that of 71%in clinical medicine papers of mainland of China. H index was 30. The average percentage of international cooperation papers in TCM colleges and universities was 17.71%, which was lower than the percentage of international cooperation papers in clinical medicine of mainland of China (22.85%). Conclusion In recent 10 years, the academic level of TCM colleges and universities in our country has been developing rapidly. However, there is still a need to further explore international perspectives, focus on research frontiers, strengthen international cooperation, carry out innovative research and improve academic influence.

After a description of the 6 types of reference management software ( EndNote, Mendeley, F1000Workspace, NoteExpress, King of medical literature and NoteFirst), their basic functions were comparatively analyzed.