Objective: To determine the content of ephedrine in Xiaoer Feiyan Zhike Granule. Meth ods: Chlorimetry is applied, the wavelength is 438 um and the linearity range is 4. 0 - 34. 0mg/L. Results: The recovery is 96. 3% and RSD is 1. 68%. Conclusion: This method is sensitive, specific and accurate and can be used to control the quality of Xiaoer Feiyan Zhike Granule.

Acetyl-11-keto-β-boswellic acid (AKBA) is one of the triterpenes in the gum resin of the Boswellia serrata and Boswellia carterii,also known as Salai guggal or Indian frankincense.There has been growing interst in anti-tumor activity of AKBA.This review will summarize the latest advances of AKBA on anti-tumor activity for the better understanding of this compound and its further applications.

Objective To design and implement the academic impact power information platform for the secondary disciplines of clinical medicine in order to keep abreast of their advantages and disadvantages. Methods An index system for the assessment of secondary disciplines of clinical medicine was constructed with the bibliometric methods according to the factual data. Results Its functions of query analysis, batch input, and editing of the index data of different disciplines were achieved in higher education institutions using the ASP. NET technology based on the data processing, indexing and statistical analysis. Conclusion The platform can provide the data support for the develop-ment and scientific research management of secondary disciplines, and thus playing an important role in promoting the innovative research and management of clinical medicine.

Objective To analyze the clinical and pathological data of the minimal deviation adenocarcinoma (MDA) of the cervix, and to provide evidence based medicine for diagnosis and treatment. Methods Clinical case reports about MDA or malignant adenoma during 1980-2014 published on CNKI, WanFang, CBM, WeiPu and Medline were retrieved and combined with 2 case with the same diagnosis and treatment. Results Age of onset was 20-86 years old, and the average age was 44.8 years, with median age of 44.5 years. Clinical symptoms of MDA showed massive vaginal apocenosis or irregular bleeding. Gynecological examination common showed cervical hypertrophic and harden. The positive rate of cervical cytology examination was 9.73% (11/113). MDA diagnosed by cervical biopsy and conization accounted for 58.38% (108/185). Immunohistochemical showed that the positive rates of carcinoembryonic antigen, P53 and Ki-67 were 93.91%(108/115), 75.44%(43/57)and 100.00% (42/42). Main operation assisted with postoperative radiotherapy and chemotherapy, early diagnosis, clinical stage and operation methods played important roles in the prognosis. Conclusions The clinical symptoms and physical signs are not obvious for MDA which is difficult to diagnose, so it is easy to diagnose mistakenly and misdiagnose also. The positive rate of cervical cytology is usually lower, repeated and deep cervical biopsy or conization combined with immunohistochemistry can improve the accuracy of diagnosis. The individualized treatment should be selected according to clinical stage for the patients who were confirmed preoperatively.

Objective To investigate the role of losartan in AT2-R mediated renal protective effects in renovascular hypertension rat. Methods Male SD rats were divided into sham group and renovascular hypertension group in which Goldblatt methods were performed. The two groups were intragastically administered with losartan (respectively 0, 10, 20, 30 mg?kg-1?d-1) for 6 weeks. Then renal function was measured, the AT2-R expression in the non-ischemic kidney and the AngⅡ contents in non-ischemic kidney and plasma were determined. Results In renovascular hypertension rats, especially in the contralateral, non-ischemic kidney, the expression of AT2-R protein were up-regulated. Losartan increased the AngⅡ contents in non-ischemic kidney and plasma, mediated the natriuretic/diuretic effect and renal protective effect in renovascular hypertension rat and increased the expression of renal AT2-R. Conclusion In renovascular hypertension rat, losartan mediates renal natriuretic/diuretic effect and protects renal function through up-regulating AT2-R in kidney.

OBJECTIVE: To probe into the causes of drug repercussion of inpatients in psychiatric hospital to promote rational drug use. METHODS: Using HIS (hospital information system), the drug repercussion data in 8 psychiatirc departments (ward pharmacy) between 2004 and 2005 were analyzed statistically. RESULTS: Of the total 203 drug repercussion cases analzyed, most were resulted from alteration of doctor’s orders, man-made entry errors of drug information, and high drug costs etc. CONCLUSION: The effective way to reduce drug repercussion is to improve technical level and working attitude, establish good rules and regulations and standardize service conditions.

Objective To introduce the current progress of research on pancreatic encephalopathy(PE). Methods Collecting related articles to make this paper.Results (1) The reported incidence of PE was from 11% to 53%. (2).The main pathogenisis of PE was large quantity of enzymes, which were secreted by the pancreas, entering the blood and crossing the blood brain barrier resulting in brain damage. (3).The demyelination could be seen on the brain pathologically. (4).The main clinical features of PE were temporal confusion, coma and neurasthenic syndrome. (5).The treatments of PE include treating underline disease, trying gabexale mesilate(Foy), a new special enzyme inhibitor, and the symptom control treatment. Conclusions PE is a dangerous complication of pancreatitis with a very bad prognosis. Evaluated myelin basic potein(MBP)may be a early, reliable biochemical parameter for diagnosis of PE. A special enzyme inhibitor Foy may be very useful in treating PE.

Objective:To study the effect of electromyographic feedback therapy on hemiplegia of patients with cerebral infarction Method: 120 hemiplegic patients were randomly divided into study group (n=60) and control group (n=60) The former received electromyographic feedback trainings, 6 times a week for four weeks, in addition to regular medication All patients were evaluated with Fugl-Meyer Assesment and Barthel Index Results: The improvement of study group was greater evaluated by both methods Discussion:The eletromyographic feedback can improve motor function of hemiplegic patients and do benefit their activities of daily living

Objective To investigate the value of transcatheter arterial embolization in the treatment of obstinate nosebleeding. Methods Twenty patients with obstinate nosebleed failed with conventional therapy were performed internal maxillary arterial angiography. Transcatheter arterial embolization were carried out immediately after occurance of nosebleeding. PVA or gelfoam particles were injected into the bleeding arteries under fluoroscopy control. Nasal packing was removed to see whether bleeding was stopped. Results Active bleeding occurred in all 20 patients during angiography but was stopped in all patients after embolization without severe complications. Conclusions Transcatheter arterial embolization is an useful mini-invasive method in the treatment of obstinate nosebleeding.

TNF in sera from BALB/c mice treated with sepia was detected by L929 cell killing assay. Sera of the mice treated with saline were used as control. Results showed a significant TNF -inducing activity of sepia in animals. And the induced sera were also cytotoxic to human cancer cells,such as GM803 and Y99.