This is a case report of a Gustilo-Anderson Type IIIB
comminuted open right tibial fracture with massive bone
loss, complicated by methicillin-resistant Staphylococus
aureus (MRSA) infection. Non-viable and contaminated
bony fragments were removed and infected bone resected.
Soft tissue coverage and antibiotics were effective against
the MRSA infection. A unifocal bone transport with the
Ilizarov method regenerated 13cm of the missing tibia.
Autologous peripheral blood stem cells (PBSC) injections
into the osteogenesis site boosted bone regeneration and
consolidation with a shortened Bone Healing index (BHI) of
23 days/cm.