1.Influence of three different therapeutic methods on intestinal flora in treating rat intestinal dysbacteriosis complicating allergic asthma
Wen FU ; Xinlong LIU ; Longqiong ZHANG ; Yongxiang GAO
Chongqing Medicine 2017;46(25):3477-3479,3483
Objective To provide a theoretical basis for the pulmonary enteric therapy in treating intestinal dysbacteriosis complicating allergic asthma according to the traditional theory of Lung and Large intestine are interiorly-exteriorly.Methods The experiment included the blank group,model group,positive control group and three kinds of traditional Chinese medicine compound administration group;the intestinal dysbacteriosis in SD rats was duplicated by adopting cefoperazone and candida albicans gavage.On this basis ovalbumin injection sensitization and nebulization were applied to induce asthma.Meanwhile Jia-Wei-ShengJiang Powder(SJS),Guizhi-Jia-Houpu-Xingzi Decoction(GHX) and Zeng-Ye-Cheng-Qi Decoction(ZYCQ) were orally administered for treatment of lung-intestine combine therapy,lung therapy and intestine therapy.The respiratory function was analyzed by using the Buxco whole body plethysmography.The variety of intestinal flora were analyzed by using 16SrDNA.Results Analyzing the specieces composition of intestinal flora in each group by the OUT value found that the recovery of Lactobacillus in each group was close to that in the blank group and better than that in the positive group,meanwhile,3 treatment groups all could promote the recovery of Proteobacteria and bacteroidetes,but the lung-intestine combine therapy had optimal effect,the Alpha diversity analysis found that the intestinal microflora diversities from high to low were in turn the intestinal therapy group,lung therapy group,lungintestine combined therapy group and model group;the respiratory frequency and airway hyperreactivity in the model group was 260.56(1.28),which in the lung-intestine combined therapy group,lung therapy and intestine therapy after treatment were 141.79 (0.93),137.25 (1.30) and 203.16 (0.84) respectively,the rat respiratory frequency in each treatment group was lower than that in the model group,while the airway hyperreactivity only in the lung-intestine combined therapy group and intestinal therapy group was lower than that in the model group,moreover showing statistical significance.Conclusion The lung-intestine combine therapy method for treating rat intestinal dysbacteriosis complicating allergic asthma is superior to simple lung therapy method or intestine therapy method.
2.Women's needs for men's participation in maternal and child health care during pregnancy: a qualitative study
Min ZHANG ; Bizhen LIAO ; Longqiong WANG ; Liu LUO
Chinese Journal of Modern Nursing 2021;27(15):1968-1972
Objective:To explore women's needs for men's participation in maternal and child health care during pregnancy, so as to provide a basis for promoting men's participation in maternal and child health care during pregnancy.Methods:This research adopted the phenomenological research method in qualitative research. From January to February 2020, purpose sampling method was used to select 11 perinatal women who underwent the obstetric examination and delivery in the First Hospital of Chongqing Medical University as the research subjects. The semi-structured interview was conducted on those women, and the Colaizzi analysis method was used to analyze the interview data and refine the theme.Results:A total of 4 themes were refined, namely the need for men to provide support during pregnancy, the need for men to participate in prenatal examinations, the need for men to participate in decision-making, and the need for men to participate in self-management during pregnancy.Conclusions:During pregnancy, women have a high need for men to participate in maternal and infant health care, and it is manifested in many aspects. Both society and hospitals should strengthen publicity and education for men, promote men's participation during pregnancy, and protect the maternal and child health.