Objective To investigate the safety and effectiveness of the spinous balloon application in coronary artery calcification.Methods A total of 80 patients with coronary artery calcification treated by per-cutaneous coronary intervention (PCI) were selected as the study subjects and divided into the control group and study group by adopting the random number table method,40 cases in each group.The control group a-dopted the routine balloon dilation and the study group adopted the spinous balloon dilation.The characteris-tics of stent implantation,intravascular ultrasound (IVUS) examination results and postoperative follow-up situation before and after coronary angiography and balloon dilation were compared between the two groups. Results The two groups all completed the PCI treatment.There were no statistically significant differences in the general data,coronary angiography and preoperative IVUS examination between the two groups (P>0.05).The number of balloon slippage in the study group was less than that in the control group[(2.72±1.23) times vs. (4.28±1.43) times,P<0.05],the operation time was shorter than that in the control group,and the difference was statistically significant[(64.34±8.73)min vs. (71.61±9.58) min,P<0.05]. There was no statistically significant difference in the anterior and posterior expansion balloon pressure of stent implantation,stent release pressure and stent length between the two groups (P>0.05).In the postop-erative IVUS examination,the immediate luminal obtaining area of the study group was larger than that of the control group[(3.76±0.87) mm2 vs. (3.33±0.67) mm2],and the minimum stent area was larger than that of the control group[(6.12±0.98) mm2 vs. (5.43±0.78)mm2],and the differences were statistically signif-icant (P<0.05),but there was no statistically difference in the poor rate of stent adhesion and loss of coro-nary dissection and blood vessel between the two groups (P>0.05).There were no statistically significant differences in the death cases,cases of stent restenosis,cases of non-fatal myocardial infarction and left ven-tricular ejection fraction during hospitalization and postoperative 6-month follow-up between the two groups (P>0.05).Conclusion The application of spinous balloon could increase the immediate lumen area and mini-mum stent implantation area,shorten the operation time and improve the stent implantation effect.

Objective To analyze the efficacy of Astragalus membranaceus and Draba nemorosa in the treatment of chronic heart failure(CHF),the change of cardiac color ultrasound parameters and its predictive value for adverse end events.Methods A total of 92 patients with Qi-deficiency and blood-stasis combined with Shuiyin CHF treated in Wenzhou Hospital of Traditional Chinese Medicine from September 2019 to September 2021 were randomly selected and divided into two groups by random number table method,with 46 cases in each group.Patients in control group were received conventional Western medicine treatment,and patients in observation group were received the addition and subtraction treatment of Yiqi Huoxue Lishui prescription based on Astragalus membranaceus and Draba nemorosa.The clinical efficacy,TCM syndrome score,heart color ultrasound parameters and the incidence of adverse endpoint events within 6 months were compared between the two groups.Cardiac color doppler ultrasound parameters were compared between the occurrence group and the non-occurrence group,and receiver operating characteristic curve was drawn to analyze the predictive value of cardiac color Doppler ultrasound parameters for adverse end events.Results The total clinical effective rate of the observation group(95.65%)was higher than that of the control group(71.74%)(P<0.05).After treatment,palpitation,weakness,shortness of breath,lethargy and lip purple score in observation group were lower than those in control group(P<0.05).The left ventricular end-diastolic diameter(LVEDD)and left arial diameters(LAD)of the observation group were lower than those of the control group after treatment(P<0.05).After treatment,the left ventricular ejection fraction(LVEF)of the observation group was higher than that of the control group(P<0.05);The incidence of adverse endpoint events within 6 months in the observation group(2.17%)was lower than that in the control group(19.57%)(P<0.05).The LVEDD and LAD in the adverse end point event group were higher than those in the without adverse end point event group(P<0.05),and the LVEF was lower than that in the without adverse end point event group(P<0.05).The area under the curve(AUC)of LVEDD,LAD and LVEF combined to predict the occurrence of adverse endpoint events was 0.812,and the 95%CI confidence interval was 0.734-0.968;The sensitivity of combined detection(93.42%)was higher than that of single detection(71.52%,75.11%,79.62%)(P<0.05).The specificity of combined detection(82.27%)compared with that of single detection(70.19%,73.07%,77.28%)(P>0.05).Conclusion Supplementing qi and promoting blood circulation and rehydrating water based on Astragalus membranaceus and Draba nemorosa can effectively improve the cardiac function of CHF patients,alleviate symptoms such as palpitations and fatigue,and reduce the incidence of adverse endpoint events.In addition,the combined detection of cardiac ultrasound parameters can improve the prediction efficiency of adverse endpoint events,which has certain clinical value.