Objective To explore the effect of surgical treatment of low back pain patients with Modic change or high intensity zone(HIZ) on MRI of the lumbar spine .Methods 32 cases with intervertebral disc herniation underwent posterior lumbar inter-body fusion and 17 cases with lumbar discogenic pain underwent radiofrequency ablation from March 2011 to July 2012 were retro-spectively reviewed .For intervertebral disc herniation patients ,all patients were divided into two groups :groupⅠ (no with Modic changes group)and groupⅡ(with Modic changes group) ,according to the Admission MRI .GroupⅡ was sub-divided intoⅡa(Mod-ic type Ⅰgroup) andⅡb(Modic type Ⅱgroup) .For lumbar discogenic pain patients ,all patients were divided into group A (without HIZ group) and group B(with HIZ group) .The VAS and ODI scales at the preoperative and follow-up were recorded and analyzed . Results The postoperative scores of VAS and ODI of all the patients were improved ,and the difference was statistically significant (P<0 .05) .For intervertebral disc herniation patients ,three groups have no statistically significant difference (P>0 .05) .For lum-bar discogenic pain patients ,the improvement rate of VAS (low backpain) of A was better than that of B ,and the difference was sta-tistically significant(P<0 .05) ,but the differences of VAS (leg pain) and ODI scores weren′t statistically significant (P>0 .05) . Conclusion Posterior lumbar interbody fusion is effective for lumbar disc herniation patients with Modic changes ,and can obtain good clinical effect .For lumbar discogenic pain patients with high intensity zone on MRI ,radiofrequency ablation can cause clinical symptoms get some relief ,but the effect is poor .

This Paper reports the histochemical changes occcured at the early acute cardial ischemic area in-duced experimentally by ligation of left coronary artery of 50 male Wistar rats. The following histo-chemical changes at the ischemical areas were observed: obvious decrease of glycogen of cardical is-chemical for 1h, of both NADHD and LDH activity of ischemical for 2h as well as CCo,CK and ATP activity of ischemical for 4h. The decrease of CCo,CK and ATP activity propagated to the whole is-chemical area at the time of ischemical for 8h. The activity of NADHD,LDH'CK and ATP can toler-ated the postmortem autolysis influence up to 24h after death.

Medicine is related to people's wellbeing,which is an eternal topic that all mankind concern.Studying on the process from the origin to the development of medicine can figure out the development rules of medicine,gain experience from it,and provide guidance for better development of medicine in the future.Medical anthropology is a new discipline which focuses on the study of disease and culture.From this special perspective,studying on the process from the origin to the development of medicine can help us to have a profound and comprehensive understanding of medicine.This paper reviewed the relevant concepts of medical anthropology and the research status and research characteristics of the origin and development of Chinese and Western Medicine,providing a reference for the colleagues.

Brain Abscess ; etiology ; Female ; Humans ; Leuconostoc ; pathogenicity ; Male ; Sepsis ; complications ; microbiology

There is still evident gap between the humanity education of medical college in China and the foreign country's.We can find the heart of the matter and explore ways of solving the problem,by comparing the present condition of the humanity education of medical college in China and the foreign country's.

Objective To study the expressions of heat shock protein 27(HSP27)in brain tissue and the changes of antibody of HSP27 in serum after transient cerebral ischemic reperfusion in gerbils.Methods A cerebral ischemia-reperfusion model in gerbils was established by clamping both common carotids.Sixty gerbils were randomly divided into normal control group,sham operation group and ischemia-reperfusion(IR)group.The expressions of HSP27 in brain tissue were detected by immunohistochemistry technique and the changes of antibody of HSP27 were detected by ELISA technique at the 6th hour,1st day,3rd and 7th day after IR.Experimental results were analyzed with the statistic soft package of Spss11.5.Results Experimental results revealed that HSP27 were expressed in neurons and gliacytes of the brain tissue in the 60 gerbils.There was mild expressions of HSP27 in neurons and gliacytes in normal control group and sham operation group, but it has no significant difference between the two groups(P＞0.05).Compared with normal control group,the expressions of HSP27 in neurong and gliacytes of ischemia-reperfusion gerbils were evidently increased at the 6th hour,1st day,3rd day and 7th day,especially at the 3rd day(P＜0.01).Conclusions Expressions of HSP27 in neurons and gliacytes of gerbils were increased markedly.This suggested that the increased expressions of HSP27 could protect the brain tissue from damage.The changes of antibody in serum of normal control group,sham operation group were evidently less than that in group IR,which suggest the HSP27 antibody may damage our body.

Objective To evaluate three dimensional digital subtraction angiography (3D DSA) in endovascular treatment of carotid stenosis. Methods In 138 patient with ischemic stroke, the shape and stenosis of carotid artery, the feasibility of endovascular treatment and the choice of the stent were analyzed by 2D DSA and 3D DSA. Results Comparing with 2D DSA,3D DSA could clearly depict the carotid artery in shape and stenosis with correct figuring of the feasibility for endovascular treatment and choice of the stent. Conclusions 3D DSA shows the major importance in endovascular treatment of carotid stenosis providing more valuable informations than 2D DSA.

Objective Try to find out the feasibility and curative effect of the treatment of DAVF with stenosed drainage vein by implantation of stent.Methods A patient of complicated DAVF with stenosed drainage vein ,stent was implanted in the stenosed drainage vein to improve the function of vien. Results The procedure was successful. The symptom of the patient improved obviously. Cerebral angiography after six month revealed the fine shape and location of the stent. The fistulas of lateral sinus and sigmoid sinus showed no obvious change comparing with the formers.Conclusions The treatment of DAVF with stenosed drainage vein by implantation of stent is feasible. The short term curative effect is satisfactory and the long-term one is still wait for follow-up.

Objective To evaluate the use of three-dimensional (3D) digital subtraction angiography (DSA) in endovascular treatment of carotid stenosis.Methods In 216 patient of ischemic stroke,carotid artery shape,stenosis,the feasibility of endovascular treatment and the choosing of the stent were analyzed at 2D DSA and 3D DSA. Results Comparing with 2D DSA,3D DSA can clearly depicted the carotid artery shape and stenosis.3D DSA can correctly judge the feasibility of endovascular treatment,can correctly choose the stent.Conclusions 3D DSA is very important in endovascular treatment of carotid stenosis.It can provide many valuable information for endovascular treatmen that 2D DSA can not provide.

Objective To investigate the effect of nicergoline on cognitive ability and executive function for patients with vascular cognitive impairment without dementia (VCIND).Methods Totally 68 patients with VCIND were divided into conventional treatment group (33 cases) and nicergoline treatment group (35 cases,nicergoline 10 mg,tid added on basal conventional treatment).All of cases were continuously treated for 12 weeks.Cognitive ability and executive function before and after treatments were evaluated.Results Test scores of immediate free recall of a list of words,the numbers and symbols transformation,the word fluency,clocks and watches painting,and minimental state examination (MMSE) were significantly higher in nicergoline treatment group than in conventional treatment group (P＜0.05).Conclusions Nicergoline may improve attention and memory as well as cognitive ability in patients with vascular cognitive impairment without dementia.