1.Imaging feature of laparoscopic ultrasound of gallbladder polyps
Journal of Practical Medicine 1998;344(1):31-33
30 patients diagnosed as gallbladder polyps by laparoscopic ultrasound of which 12 patients received operations have shown that the male/female was 1/1; the disease occurred most frequently in ages of 40-50. The gallbladder multipolyps occurred more frequently than gallbladder polyp and rate of pedicular polyps was higher than nonpedicular polyp. 36.8% of patients accompanying with other diseases such as gallbladder stone, cancer, hepatic angioma. The laparoscopic ultrasound was high precise technique for diagnosis of gallbladder polyp (11/12).
Gallbladder
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Ultrasonography
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Intestinal Polyps
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Polyps
2.Study on examining clinical characteristics, alpha feto protein and imaging features of hepatocellular carcinomas after therapy with radio frequency ablation
Diep Minh Luu ; Long Van Dao ; Phuong Minh Tran
Journal of Medical Research 2007;53(5):23-28
Background: Radiofrequency ablation (RFA) is a minimally invasive treatment for hepatocellular carcinoma (HCC). It is coming into use worldwide. Objective: To analyze clinical characteristics, AFP (alpha - feto protein), imaging features of liver tumors after treated with RFA or with RFA combined with TOCE. Subjects and method: Between August 2002 and October 2006, we ablated 87 HCCs in 76 patients (RFA alone, 41. TOCE - RFA, 35). Results: The mean age of patients was 52.8 \xb1 12. The male/female ratio was 5.9/1. The complication rate was 1.9% (5/254 sessions, 5/76 patients). Significant differences were observed in clinical symptoms: Weigh gain, abdominal pain relief, AFP decreased after treatment. Median survival was 30 \xb1 5.8 months in RFA group and 31 \xb1 5.4 months in TOCE - RFA group. 1 - 2 - 3 years survival rates were 74%; 56.3%; 43.8% in RFA group and 91.3%; 63.4%; 34.6% in TOCE - RFA group. Ablated lesions were of low attenuation with absence of contrast material enhancement and reduced in size. Conclusions: Our study results show that RFA is an effective and safe therapeutic technique for HCC. Good therapeutic effects on clinical symptoms, treated lesion and survival were achieved.
Carcinoma
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Hepatocellular/ therapy
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Alpha-Fetoproteins
3.Evaluating clinical experience from a case of hepatocellular carcinoma with combinated therapy of transarterial chemoembolization and percutaneousethanol injection afterward emerging metatasis caused by fine needle aspiration cytology
Long Cong Nguyen ; Truong Xuan Bui ; Thong Minh Pham ; Ho Thi Thu Pham ; Hung Quoc Nghiem ; Phuong Minh Tran ; Long Van Dao ; Trach Khanh Nguyen
Journal of Medical Research 2007;47(2):69-73
Background: Hepatocellular carcinoma (HCC) is the most common primary hepatic tumor and one of the most common cancers worldwide. HCC is a primary malignancy of hepatocellular origin. Objectives:The aim of study is to combinate therapy of transarterial chemoembolization and percutaneousethanol injection afterward emerging metatasis caused by fine needle aspiration cytology. Subjects and method: A 50 years old male patient with hepatocellular carcinoma having a diameter of tumor more than 5 cm was treated by combination of transarterial chemoembolization and percutaneous ethanol injection from December 2000. Results & Conclusion: Results of study showed that: Transarterial chemoembolization and percutaneous ethanol injection are the two of non-surgical methods for treatment of hepatocellular carcinoma which are most commonly available in applied clinical activities at present. Up to now, the patient's life expectancy after therapy is more than 6 years that means the result of treatment is very good. However, the emerging metatasis into the anterior-right-Iower chest wall that was caused by fine needle aspiration cytology should be reviewed for further evaluating clinical experience, especially in cases with quite clear imaging features of untrasonography and significantly elevated AFP level higher than 200 ng/rnl.
Carcinoma
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Hepatocellular/ pathology
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therapy
4.Healthcare Workers’ Knowledge and Attitudes Regarding the World Health Organization’s “My 5 Moments for Hand Hygiene”: Evidence From a Vietnamese Central General Hospital
Huy Van NGUYEN ; Hieu Trung TRAN ; Long Quynh KHUONG ; Thanh Van NGUYEN ; Na Thi Nhi HO ; An Thi Minh DAO ; Minh Van HOANG
Journal of Preventive Medicine and Public Health 2020;53(4):236-244
Objectives:
Although the World Health Organization (WHO) initiative “My 5 Moments for Hand Hygiene” has been lauded as effective in preventing hospital-associated infections, little is known about healthcare workers (HCWs)’ hand hygiene behavior. In this study, we sought to assess knowledge and attitudes towards the concepts in this initiative, as well as associated factors, among Vietnamese HCWs at a general hospital.
Methods:
A structured questionnaire was administered to HCWs at a central Vietnamese general hospital in 2015. Multiple logistic regression analysis was used to identify factors associated with HCWs’ knowledge and attitudes towards hand hygiene.
Results:
Of 120 respondents, 65.8% and 67.5% demonstrated appropriate knowledge and a positive attitude, respectively, regarding all 5 hand hygiene moments. Logistic regression indicated better knowledge of hand hygiene in workers who were over 30 years old, who were direct HCWs (rather than managers), who had frequent access to clinical information, and who received their clinical information from training. Those who worked in infectious and tropical disease wards, who had frequent access to clinical information, and who received information from training were more likely to have a positive attitude towards hand hygiene than their counterparts.
Conclusions
Although many Vietnamese HCWs displayed moderate knowledge and positive attitudes towards the WHO hand hygiene guidelines, a key gap remained. Regular education and training programs are needed to increase knowledge and to improve attitudes and practices towards hand hygiene. Furthermore, a combination of multimodal strategies and locally-adapted interventions is needed for sustainable hand hygiene adherence.
5.Clinical and Laboratory Characteristics of Kawasaki Disease and COVID-19-Related Multisystem Inflammatory Syndrome in Children
Duc Long PHI ; Thi Loi DAO ; Minh MANH TO ; Thanh Binh NGUYEN ; Duy Cuong NGUYEN ; Philippe GAUTRET ; Van Thuan HOANG
Journal of Korean Medical Science 2023;38(49):e410-
Geographical and racial factors constitute important distinctions between Kawasaki disease (KD) and multisystem inflammatory syndrome in children (MIS-C), but no study has been conducted in Vietnam. Forty-one children with KD from January 2018 to July 2020 and 42 with KD/MIS-C from August 2020 to December 2022 were included in this study. Of the patients, 52.3% were aged between 12 and 35 months. Only two were aged over 5 years, and both were belong to the KD/MIS-C group. A 59.5% of the patients were male. Apart from fever, all symptoms tended to be more frequent in patients with KD/MIS-C. The prevalence of diffuse skin rash, hand and foot edema or erythema and gastrointestinal signs was significantly higher in patients hospitalized with KD/MIS-C. There was no significant difference in laboratory findings between the two groups. Coronary artery dilation was more frequently observed in patients with KD/MIS-C compared to those with KD (40.5% vs. 14.6%, P = 0.009).
6.Field and laboratory investigation of highly pathogenic avian influenza H5N6 and H5N8 in Quang Ninh province, Vietnam, 2020 to 2021
Trong Duc TRAN ; Suwicha KASEMSUWAN ; Manakorn SUKMAK ; Waraphon PHIMPRAPHAI ; Tippawon PRARAKAMAWONGSA ; Long Thanh PHAM ; Tuyet Bach HOANG ; Phuong Thi NGUYEN ; Thang Minh NGUYEN ; Minh Van TRUONG ; Tuan Pham DAO ; Pawin PADUNGTOD
Journal of Veterinary Science 2024;25(2):e20-
Background:
Avian influenza (AI) is a contagious disease that causes illness and death in poultry and humans. High pathogenicity AI (HPAI) H5N6 outbreaks commonly occur in Quang Ninh province bordering China. In June 2021, the first HPAI H5N8 outbreak occurred at a Quang Ninh chicken farm.
Objectives:
This study examined the risk factors associated with HPAI H5N6 and H5N8 outbreaks in Quang Ninh.
Methods:
A retrospective case-control study was conducted in Quang Ninh from Nov 2021 to Jan 2022. The cases were households with susceptible poultry with two or more clinical signs and tested positive by real-time reverse transcription polymerase chain reaction. The controls were households in the same village as the cases but did not show clinical symptoms of the disease. Logistic regression models were constructed to assess the risk factors associated with HPAI outbreaks at the household level.
Results:
There were 38 cases with H5N6 clade 2.3.4.4h viruses (n = 35) and H5N8 clade 2.3.4.4b viruses (n = 3). Compared to the 112 controls, raising poultry in uncovered or partially covered ponds (odds ratio [OR], 7.52; 95% confidence interval [CI], 1.44–39.27), poultry traders visiting the farm (OR, 8.66; 95% CI, 2.7–27.69), farms with 50–2,000 birds (OR, 3.00; 95% CI, 1.06–8-51), and farms with ≥ 2,000 birds (OR, 11.35; 95% CI, 3.07–41.94) were significantly associated with HPAI outbreaks.
Conclusions
Combining biosecurity measures, such as restricting visitor entry and vaccination in farms with more than 50 birds, can enhance the control and prevention of HPAI in Quang Ninh and its spread across borders.
7. Anti-inflammatory effects of alkaloid enriched extract from roots of Eurycoma longifolia Jack
Dao Thi Thanh HIEN ; Tran Phi LONG ; Tran Phuong THAO ; Jeong-Hyung LEE ; Duong Thu TRANG ; Nguyen Thi Thu MINH ; Pham VAN CUONG ; Nguyen Hai DANG ; Do Thi Ngoc LAN ; Nguyen Tien DAT
Asian Pacific Journal of Tropical Biomedicine 2019;9(1):18-23
Objective: To examine the in vitro and in vivo anti-inflammatory effects of the alkaloid enriched extract (ELA) from the roots of Eurycoma longifolia. Methods: The in vitro antiinflammatory effects of ELA were evaluated by examining its inhibitory activities against nitric oxide (NO) production and inducible nitric oxide synthase (iNOS) and cyclooxygenase 2 (COX-2) expressions in lipopolysaccharide (LPS)-stimulated RAW264.7 cells. The level of NO produced in the culture media was determined by Griess method. The iNOS and COX-2 protein expressions were analyzed by Western blot. The in vivo effect of ELA was evaluated on LPS-induced septic shock in mice model. Mice mortality was monitored for 5 days after injection of LPS. The chemical contents of the ELA were determined by using various chromatographic and spectroscopic techniques. Results: The ELA was found to exhibit a significant anti-inflammatory effect in both in vitro and in vivo models. The results demonstrated that ELA dose-dependently inhibited LPS-induced NO production as well as the protein iNOS and COX-2 expressions. In the septic shock model, ELA dose-dependently protected mice from LPS-induced mortality. Further study on the isolated components of ELA indicated that 9,10-dimethoxycanthin-6-one may contribute significantly to the anti-inflammatory effects of the extract. Conclusions: These results suggest that ELA exhibits the anti-inflammatory activity via suppression of pro-inflammatory mediators such as NO, iNOS, and COX-2 and protects mice from LPS-induced mortality in septic shock model.