Forehead ; surgery ; Humans ; Nose ; surgery ; Reconstructive Surgical Procedures ; methods ; Surgical Flaps

Objective To develop a physical in vitro model of the human carotid artery(CA) and analyze the factors that influence the embolus-capturing efficiency of the retrievable artery filters. Methods The flow model closely simulated the physiological parameters of the human carotid artery. The influence of the following experimental parameters on the capturing rate was analyzed with a multiple logistic regression model: embolus diameter and length, CA diameter, flow quantity, type of filter, and type of testing. Results At the 5% level,except for flow quantity,a significant influence on the capturing rate could be demonstrated for the 6 factors mentioned above, the embolus diameter was the strongest influencing factor. In CA with diameters of 4,5,6,7 mm, the 8-wire filter captured (90?7)%, (91?8)%, (81?8)%,and (68?9)% of 0.5 mm emboli and (93?4)%, (95?6)%, (95?6)%,and (82?11)% of 1 mm emboli. In all, the smaller, the interlacing opening of the filter, the higher the capturing rate, and the presence of an embolus in a filter would decrease the capturing rate for the second embolus. Conclusion Retrievable artery filter is a promising cerebral protection device. The physical in vitro model is an effective alternative in studying the influence factors of the capturing rate of the filters.

Cardiac involvement related to iron overload caused by long-term blood transfusion is a major cause of death for patients with thalassemia major. Patients' survival will be improved greatly if cardiomyopathy resulted from transfusional iron overload could be detected timely and effective iron chelation be initiated promptly. In the present article, various evaluation Methods currently used in clinical practice are reviewed, with particular focus on cardiac MRI for the monitoring of myocardial involvement related to iron overload.

Objective: To study the loss of heterozygosity (LOH) at 6 markers of microsatellite polymorphism on the chromosome 6 in T-cell lymphoma (TCL) to determine whether there existed tumor suppressor genes in the area related with the initiation and development of TCL. Methods: Six microsatellite polymorphism markers (D6S251, D6S275, D6S287, D6S267, D6S262, and D6S264) on the chromosome 6 were selected. We performed the amplification of microsatellite DNA with PCR, polyacrylamide gel electrophoresis and silver staining to detect LOH in 42 cases of T-cell lymphoma and the corresponding normal tissues. Results: LOH were detected at more than one locus in 13 out of 42 TCL patients (30.95%). Among the 6 loci, LOH occurred more frequently at D6S262 (10.3%), D6S287 (10.0%), and D6S267 (7.3%). No significant difference was found in LOH incidence between different clinicopathologic classifications (P > 0.05). Conclusion: The LOHs occur more frequently at markers D6S262, D6S287, and D6S267 on the chromosome 6q21 to 6q23. Cyclin C gene localized to chromosome 6q21 may be the candidate of tumor suppressor gene related with initiation and progression of TCL. Chromosome 6q21-6q23 may harbor a tumor suppressor locus which was related with TCL.

Child ; Humans ; Liver Failure ; therapy ; Liver Transplantation ; Male ; Plasma Exchange

Acupuncture Therapy ; instrumentation ; Adolescent ; Adult ; Child ; Child, Preschool ; Female ; Hot Temperature ; Humans ; Male ; Mumps ; therapy ; Sulfur ; chemistry ; Young Adult

Fusion Proteins, bcr-abl ; genetics ; Humans ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive ; complications ; genetics ; Male ; Middle Aged ; Precursor Cell Lymphoblastic Leukemia-Lymphoma ; etiology

Adult ; Cadmium ; Female ; Glomerulonephritis, IGA ; etiology ; Humans ; Occupational Exposure

OBJECTIVE: To screen the fungi which can induce Aquilaria sinensis to produce active substance. METHODS: Fungus was inoculated in the stem of A. sinensis under natural conditions. The penetration and planting of fungus in stem of A. sinensis as well as the interaction of the two organisms were studied by microscope and scanning electron microscopy, and the main ingredients of the volatile oil in induced agilawood were analysed by GC-MS. RESULTS: Three active strains inducing the formation of agilawood were obtained, which was reported for the first time in the world. The main ingredients of the volatile oil were similar between the induced agilawood and the natural materials. CONCLUSION: It is very important for us to use the fungus in the induction of agilawood and in the sustainable utilization of this special medicinal material. Copyright 2012 by the Chinese Pharmaceutical Association.

Aim To investigate the effects of curcumol on the contractile activity of isolated jejunum and ileum smooth muscles in rats and explore its underlying mechanism. Methods Jejunum and ileum specimens were randomly divided into five groups (n = 12) : curcumol group, atropine plus curcumol group, isoprena- line plus curcumol group, norepinephrine plus curcumol group, Ca2t and curcumol group. The contractile amplitude and tension of jejunum and ileum were recorded by constant temperature perfusion. Results Curcumol promoted the contraction of normal intestinal smooth muscles and antagonize the effects of atropine, norepinephrine, isoprenaline and verapamil on relaxation of intestinal smooth muscles. Conclusions Curcumol can significantly promote the contraction of isolated jejunum and ileum smooth muscles, which may be achieved through M receptor, a receptor, p receptor and promoting extracellular calcium influx.