Cutis marmorata telangiectatica congenita (CMCT) is an uncommonly reported, sporadic, congenital cutaneous disorder with persistent cutis marmorata, telangiectasia, and phlebectasia. It may be associated with a variety of other congenital anomalies, including but not limited to undergrowth or overgrowth of an involved extremity. We report a case of a baby with CMCT.

Uveitis is a well-documented presentation of syphilis with or without concomitant HIV infection1,2. Syphilitic uveitis occurs most frequently during secondary and tertiary phases of the infection and its prevalence has declined in tandem with the decline in syphilis prevalence during the early phase of the HIV epidemic. However, during the past 5 years, there has been a resurgence of syphilis and an increased number of patients with ocular syphilis has been reported3,4. Early diagnosis of ocular syphilis which is highly amenable to simple antibiotic treatment can prevent blindness. Unfortunately, the ocular manifestations of syphilis are indistinguishable from that of other causes. Hence, a high index of suspicion is necessary to diagnose syphilitic uveitis. Awareness and recognition of concurrent syphilitic skin involvement, often mistaken for psoriasis, can aid in the diagnosis. We describe a patient whose ocular syphilis was diagnosed and treated promptly because of the presence of a palmoplantar rash.

Understanding of antibody kinetics against SARS-CoV-2 and its vaccines is rapidly evolving. This study aims to (1) determine post-vaccination seroprevalence; (2) compare antibody levels between vaccine types and various clinical/demographic determinants; and (3) determine post-vaccination antibody concentrations against time. This is a retrospective cross-sectional study involving 148 healthcare employees all over Malaysia. IgG Spike (RBD), IgM Spike and IgG Nucleocapsid concentration medians were compared using Mann-Whitney U or Kruskal-Wallis tests. Chi Square and Spearman correlation coefficient tests were performed to identify variables associated with antibody titers. A scatter plot of IgG Spike (RBD) against time from last vaccine dose was also plotted. At 1-month post-vaccination, all employees successfully seroconverted regardless of vaccine type, health status and COVID19 history. Comirnaty, convalescent, female or Malay vaccinees had significantly higher IgG Spike (RBD) titers compared to their respective counterparts. No correlation was found between age and IgG Spike (RBD) levels. Concentration of all three antibodies waned with time post-vaccination, with IgM Spike and IgG Nucleocapsid waning faster than IgG Spike (RBD).