1.Risk factors profile for cardioembolic stroke: A case-control study
Uurtsaikh G ; Batmyagmar K ; Dosjan E ; Saruul Ts ; Ariyasuren L ; Nandintsetseg B ; Baasanjav N ; Lkhamtsoo N
Mongolian Medical Sciences 2021;196(2):13-20
Introduction:
In Mongolia, data on the etiology and risk factors of cardioembolic stroke (CES) is scarce and few
clinical studies have been performed to date. Timely identification and control of cardiovascular risk
factors are priority objectives for adequate primary and secondary prevention of CES.
Goal:
The goal of this study was to describe risk factors for CES in our setting.
Results:
The case-control study enrolled a total of 525 subjects. CES was detected in 63 (35.7%) out of
176 (33.5%) ischemic stroke patients with a predominance in age group of 60-69 and men (33%).
The main risk factor of CES was non-valvular atrial fibrillation (AF). AF especially paroxysmal AF
increased the risk of CES by 4.6 times (p=<0.0001, OR 4.6, 95% CI 1.4-44.6). The second main
cerebrovascular risk factors were hypertension and dyslipidemia.
Conclusion
CES accounted for 1/3 of ischemic stroke. The commonest underlying medical conditions were non-valvular atrial fibrillation, hypertension, dyslipidemia, alcohol consumption and obesity. Hence, all
patients with hypertension and non-valvular AF should be meticulously screened for prevention of
CES.
2.Etiology and risk factors of intracerebral hemorrhage
Dembereldorj S ; Bayarmaa P ; Jargalsaikhan S ; Tovuudorj A ; Shin-Joe Yeh ; Lkhamtsoo N
Mongolian Journal of Health Sciences 2025;88(4):178-182
Background:
Non-traumatic intracerebral hemorrhage (ICH) represents the most devastating subtype of stroke, charac
terized by spontaneous bleeding into the brain parenchyma. This neurological emergency carries a burden of mortality
and long-term disability worldwide. Timely identification causal pathways is priority objective for adequate primary and
secondary prevention of ICH. Risk factors may differ between ICH subtypes, and stratified approaches to management
may be appropriate.
Aim:
This study is to identify cause and risk factors of ICH.
Materials and Methods:
A single centre descriptive study was carried out in Stroke Center of the State Third Central
Hospital, Mongolia, including 718 consecutive acute patients with ICH during October 2022 to September 2024. Patients
were classified using SMASH-U, an etiological based classification system.
Results:
Out of a total of 718 cases diagnosed with ICH, hypertension caused 75.3%, amyloid angiopathy 12%, undetermined 7%, structural lesions 2.92%, systemic disease 2.37%, medication 0.48% in 718 ICH patients. The mean age of
the cases was 57.5 жил, and was the most common in men of the 50-59 age group (p<0.001). The main risk factor in hypertension and amyloid angiopathy groups was arterial hypertension (93.7%), in undetermined group alcohol consumption (48%), in structural group AVM and other vascular causes (23.8%), in systemic group chronic kidney insufficiency
(29.4%), in medication group atrial fibrillation (100%), respectively.
Conclusion
1. ICH was mostly caused by hypertension, amyloid angiopathy, systemic disease.
2. Arterial hypertension, heart disease, atrial fibrillation, previous stroke, oral anticoagulants, smoking, alcohol consumption, obesity/BMI≥25, liver cirrhosis, chronic kidney insufficiency, AVM and other structural anomalies were
the most common risk factors.