1.Outcomes of percutaneous coronary intervention of coronary left main disease
Batmyagmar Khuyag ; Surenjav Chimed ; Lkhagvasuren Zundui
Mongolian Medical Sciences 2019;190(4):14-18
Introduction :
The left main (LM) bifurcational stenting is coronary high risk interventional procedure (CHIP) which
associated with various post procedural outcome.
Goal:
In this study, we aimed to describe current practice of coronary left main bifurcational stenting and
patient’s outcome in Mongolia.
Materials and Methods:
We selected 50 patients who gave informed consent and treated by left main bifurcational stent. All
the patients gave informed consent form which was approved by ethical committee of Mongolian
National University of Medical Sciences. Coronary stenosis was evaluated by Syntax score and
Medina classification. The 1 year survival rate was estimated using Kaplan-Meier estimation.
Results :
A total of 50 patients who received LM bifurcational stent were chosen (mean age 60±11, male
gender 78%). Mean syntax I score was 26.1±8.6 and mean Syntax II score was 44.7±6.2. Medina
110 type lesion was 46% (n=23), medina 111 type lesion was 36% (n=18), medina 100 type lesion
was 6% (n=3), medina 011 type lesion was 4% (n=2) and medina 010 type lesion was 8% (n=4).
The median degree of stenosis was 50% (IQR 30%; 90%) for LM, 90% (IQR 80%; 99%) for LAD and
0% (IQR 0%; 80%) for LCx. The final procedural success with final TIMI 3 flow was achieved in 44
patients (88%). All-cause mortality was occurred 5 patients during follow-up and survival rate at the
1 year was 82% (95% CI 66; 97).
Conclusion
The bifurcational stenting is acceptable treatment choice which has good survival for high risk patients
with LM bifurcational disease.
2.Impact of urgent and elective percutaneous coronary intervention on outcomes of patients with left main coronary artery bifurcational stenosis
Bum-Erdene Batbayar ; Oyunkhand Buyankhishig ; Gereltuya Choijiljav ; Surenjav Chimed ; Lkhagvasuren Zundui ; Batmyagmar Khuyag
Mongolian Medical Sciences 2021;198(4):33-39
Introduction:
Left main coronary artery (LMCA) is a large vessel which supplies the majority of left ventricle and
critical lesion at the bifurcation of LMCA can lead to life threatening condition. Therefore, percutaneous
coronary intervention (PCI) on LMCA bifurcational stenosis is considered as a complex high risk
indicated patient and procedure (CHIP).
Goal:
In this study, we investigated the impact of urgent and elective PCI on outcomes of patients with
LMCA bifurcational stenosis.
Materials and Methods:
Patients who underwent for urgent PCI due to acute myocardial infarction (AMI) or elective PCI due
to stable coronary artery disease (CAD) for their LMCA bifurcational stenosis. Any lesion with >50%
stenosis on coronary angiography was considered as a critical stenosis. LMCA bifurcational stenosis
was evaluated by Medina classification. Difference between urgent and elective PCI group were
compared by independent sample t-test and chi-square test. Association between treatment strategy
(urgent or elective PCI) and prognosis were evaluated by Cox proportional hazard regression, and
survival rate was evaluated by Kaplan-Meier methods. Ethical approval was taken from the ethical
committee of the Health Science University of Medical Sciences (№30/1А) in June 12, 2012.
Results:
A total of 82 patients with LMCA bifurcational stenosis were included (mean age 62±11, male 76.8%)
and 14 of them underwent urgent PCI due to AMI and 68 of had elective PCI due to stable CAD.
Patients who underwent urgent PCI had significantly higher 30-day mortality (1.5% vs. 21.4%, p<0.05)
and all-cause mortality (7.4% vs. 35.7%, p<0.003) compared to the elective PCI group. Urgent PCI
for LMCA bifurcational stenosis due to AMI was associated with increased risk of death (HR=3.63, 95% CI 1.02-12.9, p<0.05). Kaplan-Meier estimation showed that patients in the urgent PCI group
had significantly lower survival compared to the elective PCI group.
Conclusion
Unanticipated urgent PCI for patients with LMCA bifurcational stenosis due to AMI is associated with
higher risk of short and long-term mortality. Patients who underwent urgent PCI for LMCA bifurcational
stenosis had significantly lower survival compared to elective PCI group.
3.Antibiotic consumption in infants and toddlers
Gan-Undral Munkhjargal ; Ariunaa Zundui ; Tserenchunt Ganbold ; Munkhdelger Baasan ; Lkhagvasuren Tsolmon ; Oyunbileg Sharavdorj ; Unurjargal Yadmaa
Mongolian Pharmacy and Pharmacology 2025;26(1):17-21
Introduction:
Antibiotics are commonly prescribed in paediatrics.1 Children were 1.3 times more likely to be treated with antibiotics compared to adults.2 Especially, antibiotic prescription is higher in children aged under 5 years.3
Purpose:
To identify the most widely used antibiotics in the age group of 0-5.
Objectives of the study:
1. To identify the most widely used antibiotics and classify them by pharmacological group
2. To analyze the pharmaceutical dosage forms of commonly prescribed antibiotics for infants and toddlers
Methods:
In our study, we selected 20 pharmacies from 6 districts (Bayanzurkh, Bayangol, Khan-Uul, Songinokhairkhan, Chingeltei, and Sukhbaatar) of Ulaanbaatar city using a single random sampling method. A total of 496 antibiotic prescriptions written for children aged 0-5 years in 20 pharmacies were analyzed. Antibiotic prescription forms for children aged 0-5 years registered in the pharmacies in November, December 2023, and January 2024 were collected. The results were processed using “SPSS 29.0.2” program.
Result:
Among a total of 496 antibiotic prescriptions written for children, 341 were written in solid dosage form and 155 were in liquid dosage form (suspension). Amoxicillin 250 mg and Amoxiclav 312.5 mg were mostly used from Penicillin group for the treatment of infants and toddlers. Clarithromycin 125mg/5ml from Macrolide group had an important role in treatment. Cefixime 400 mg from the Cephalosporin group was used in some cases such as diarrhea and vomit.
Conclusions
1. Amoxicillin, Amoxiclav, Clarithromycin (Penicillin, Macrolide) antibiotics are the most widely used in the treatment
of infants and toddlers.
2. It has concluded that antibiotic prescriptions for infants and toddlers mainly include solid and suspension antibiotics.