1.The linear position tracking servo system using a linear voice-coil motor
Journal of Pharmaceutical Analysis 2008;20(3):164-167
More and more linear servo systems have been used in servo applications. Direct drive technology can greatly increase the bandwidth and the tracking accuracy. A position servo-system based on linear voice-coil motor was designed for one linear oscillation movement application. Besides the conventional position, speed and current control loops, the speed and acceleration feed-forward control of command position signal were also used. The experimental test proved the correctness of the design, and the system can track the given periodic sinnsoid position command signal of 15Hz with high accuracy. The linear voice-coil motor is very suitable for short stroke position tracking application with high dynamic response.
2.Effect of Tetramethylpyrazine on the Function of Endothelial Progenitor Cells in vitro
Jie LIN ; Lixin XU ; Deye YANG
Journal of Zhejiang Chinese Medical University 2006;0(05):-
[Objective] This study was to investigate the effect of TMP on function of EPCs in normal or hydrogen peroxide(H2O2)inducing injury model cell culture,and to approach a therapy to coronary heart disease(CHD).[Method] Total mononuclear cells were isolated from the cord blood by ficoll density gradient centrifugation,cultured in vitro.After the cells cultured for 7 days,identified them by cellmarkers and the ability of intaking the ac-LDL,and made sure they were EPCs.To divide the cells into three groups,TMP(5,25,100,200mg),H2O2(500??)model and TMP together with H2O2,cultured for 24h and then detected the function and apoptosis of EPCs.[Result] Versus to control group,the TMP(5,25,100mg)groups had no important effect on the proliferation and adhesion of EPCs,but TMP(200mg)group had negative effect on EPCs.Versus to H2O2 model group,TMP(5,25,100mg)preincubated groups had important protective effect on EPCs in proliferation,adhesion and apoptosis.[Conclusion] TMP could protect EPCs from oxidative stress injury,but had little benefit to EPCs in normal incubation.
3.Midterm results of bipolar artificial femoral head arthroplasty in treatment of elder femoral neck fracture
Lixin YANG ; Shuangjin SANG ; Jianhao LIN
Orthopedic Journal of China 2006;0(18):-
[Objective]To discuss the midterm effects of bipolar artificial femoral head arthroplasty in treatment of elder femoral neck fracture.[Method]From September 1995 to Febuary 2005,73 elderly patients with femoral neck fracture were operated with domestic bipolar artificial femoral head arthroplasty (average 74 years old).Forty-seven cases had been followed up for average 65 months.Harris score system and X-ray had been used for evaluation.[Result]There was no vessel and nerve injury,no infection and dislocation,no perioperative death.The complications included one greater trochanteric fracture,3 cases with pneumonitis,2 urinary infection,1 cerebral infarction,1 dysfunction in central nerve system and 1 case with deep venous thrombosis.Of all the 36 X-rays there were 3 cases with prosthesis subsidence,lucent line lesser 2mm in 2 cases,narrow joint space in 21 cases,protrusion in 1 case.According to the Harris scoring system,there were excellent in 12,good in 26,fair in 7,poor in 2.[Conclusion]Bipolar artificial femoral head arthroplasty are reasonable choice for treatment of femoral neck fracture in the elderly.Proper indication and perioperative management is critical to get good results.
4.Studies on Chemical Constituents of the Roots of Blackberrylily(Belamcanda chinensis)
Lixin ZHOU ; Mao LIN ; Lanfeng HE
Chinese Traditional and Herbal Drugs 1994;0(01):-
Nine known compounds were isolated from the chlorofrom soluble fraction of ethanolic extract of Belamcanda chinensis(L. )DC.. Their structures were identified as irigenin(Ⅰ),dichotomitin(Ⅱ),irisflorentin (Ⅱ),3-stigmastenol (Ⅳ), apocynin (Ⅴ), tectoridenin (Ⅵ), ?-sitosterol (Ⅶ), 3', 4', 5, 7-tetrahydroxy-8-methoxyisoflavone (Ⅶ)and polyoctapenten (Ⅹ) by spectorscopic methods (UV, IR, EIMS, 1HNMR, 13CNMR). Compounds Ⅱ, Ⅳ, Ⅹ and Ⅻ were obtained for the first time from the plant.
5.Relative Risk of Gallbladder Cancer in Patients with Gallbladder Stones
Lixin WANG ; Guosheng LI ; Fajian LIN
Chinese Journal of Digestion 1996;0(S1):-
A case-control study was performed to investigate the relationship between gallbladder cancer(GCA) and gallbladder stones (GS). 43 patients with GCA confirmed by pathology were included, in which 19 were accompanied by GS, 24 patients without. 88 controls were selected from the data for the periodic health checkup with B-ultrasonography(B-US): cholelithiasis were discovered in 6 controls, but 82 were free from GS. The difference between the case and control group was significant(P
6.Experimental study of co-immunizations of HIV-1 gag-hIL-2 recombinant vaccinia virus and DNA vaccine pIRES-gag-hIL-2
Lixin WANG ; Jun LIN ; Hongwei WANG
Chinese Journal of Blood Transfusion 1988;0(04):-
Objective To obtain recombinant vaccinia viruses of gag gene,and hIL 2 gene of HIV 1CN subtype B,evaluate the immune effects after immunization together with nucleic acid vaccine for AIDS vaccine development.Methods gag gene,and hIL 2 gene were inserted downstream of the combined promotor of pJ38 vector.Recombinant vaccinia viruses were selected by using plaque assay.Expression products were examined by SDS PAGE and Western blot.Immune response of BALB/c mice immunized was evaluated by lymphocyte transformation test and OD value of serum IgG antibody.Results Recombinant vaccinia viruses vJ38gag IL 2 were obtained with reactinogenicity.Effect of recombinant vaccinia viruses immunized three times was better than that immunized two times.The best result was obtained in the rVV primed and nucleic acid vaccine boosted group.Conclusion Gag protein and IL 2 protein can be expressed in vJ38gag IL 2
7.Development of integration information inquiry and statistics system for Civil Patients with Medical Insurance
Jinan LIN ; Lixin CHEN ; Jiansong SHANG
Chinese Medical Equipment Journal 2003;0(12):-
This paper develops an integration information inquiry and statistics system for Civil Patients with Medical Insurance on the basis of PowerBuilder 9.0.It helps departments of medicare auditing and medicare settlement obtain integration information of patients.
8.Nutritional assessment and intervention of hand-foot-mouth disease in children
Journal of Clinical Pediatrics 2013;(9):854-857
Objectives To conduct nutritional risk assessment analysis of hand-foot-mouth disease in children and to explore rational and feasible nutritional intervention. Methods The information of children with hand-foot-mouth disease in three hospitals in Guilin area was collected by ifxed-spot continuous sampling. Inquiry investigations, physical mea-surements combined with clinical diagnosis were undertaken, and nutritional risk assessment and management were con-ducted by the malnutrition screening tool of children (STAMP scoring). Those with STAMP scores ≥4 were considered at high nutritional risk. Nutritional risk reassessment was conducted on children with high nutritional risk after nutritional intervention and management. Results A total of 192 children with hand-foot-mouth disease were selected. The occur-rence rate of high nutritional risk was 68.75%(132/192). The hospitalization time of patients with high nutritional risk was prolonged and the hospitalization expense was increased apparently. The nutritional support treatment and nutritional edu-cation were undertaken on the children with high nutritional risk. The incidence of high nutritional risk from admission to discharge decreased from 68.75%to 36.98%(P<0.05). The clinical outcomes of those children accepting nutritional inter-vention were signiifcantly improved (P<0.05). Conclusions The occurrence and prognosis of hand-foot-mouth disease is closely related to the nutritional status of children, so nutritional risk assessment, nutritional intervention and management should be performed as early as possible.
9.Quality standard for Pheretima Dispensing Granule
Lin HE ; Xiaoying LONG ; Lixin XIE ; Fu CHEN ; Danrong LIN
Chinese Traditional Patent Medicine 1992;0(08):-
AIM:To establish the quality standard for Pheretima Dispensing Granules.METHODS:Pheretima Dispensing Granules were identified by TLC.The content of hypoxanthine in Pheretima Dispensing Granules was determined by HPLC,and succinic acid by high performance capillary electrophoresis HPCE.RESULTS:Spots obtained from the test solutions had the same color as amino acid reference solution,Pheretima reference substance and the blank solution had no interference.The contents of hypoxanthine were in the range of 1.6 mg/bag-3.3 mg/bag and succinic acid 23.58 mg/bag-35.38 mg/bag in Pheretima Dispensing Granules,respectively.CONCLUSION:The methods of identification and quantification were accurate,realizable and reproducible.It can be used effectively for the quality control for Dispensing Granules.
10.The protective effects of pretreatment with Lipo-PGE1 on fiver injury after hemorrhagic shock and resuscitation in rats
Jie LIN ; Jianying LI ; Lixin WEI ; Yuehong HUANG ; Zhixin CHEN
Chinese Journal of Emergency Medicine 2011;20(5):502-506
Objective To observe the effects and mechanism of pretreatment in rats with prostaglandin E1 on liver after hemorrhagic shock and resuscitation(HSR).Method In total,32 male SD rats were randomly(random number)divided into four groups(n=8):group A(sham group),group B(shock group),group C(HSR group)and group D(Lipo-PGEl+HSR).In group B,rats were sacrificed 90 min after shock,and in group C,rats were anesthetized and then subjected to hemorrhagic shock followed by resuscitation.In group D,rats were pretreated with Lipo-PGEI one hour before HSR.Liver function,NO and ET.1 were measured,and pathological changes of liver tissue in each group were observed,and the expres8ions of iNOS and ET.1 of liver tissue were measured by using immunohistochemistry 6 hours after HSR.Data were analyzed by analysis of variance,and P<0.05 was considered as significantly different in statitistics.Results The levels of liver iNOS and ET-I increased in HSR group compared with shock group [(O.225±0.080)vs.(0.082±0.021)and(0.292±0.047)vs.(0.082±0.035),P<0.05].Pretreatment with Lipo-PGEl markedly reduced the damage of Liver function,and lowered the levels of NO and ET-I.which were consistent with decrease in iNOS and ET-16 hours after HSR[(0.116±0.034)vs.(0.225±0.080)and(0.198±0.041)vs.(0.292±0.047),P<0.05].Conclusions Pretreatment with Lipo-PGEl could reduce liver injury after HSR.The mechanisms might be attributed to inhibiting iNOS and ET-1,regulating the balance of NO/ET-I.