Objective To investigate the clinical significance of DHS and LCP in treating elderly patients with intertrochanteric fracture.Methods 58 elderly patients were randomly divided into 2 groups.30 of them( DHS group) were treated with DHS,while 28 cases of them were treated with LCP.Blood loss,operation time,bone healing time and Harris score were analyzed.After 1-year follow time,effective rate and complication rate were also recorded and evaluated in the 2 groups.Results The complication rate in LCP group was lower than that in DHS group(P ＜0.05),while the effective rate and Harris score in LCP were higher than that in DHS group( P ＜0.05 ).There were no significant differences in blood loss,operation time and bone healing time between the 2 groups ( P ＞ 0.05 ).Conclusion Compared with DHS,LCP is effective in treating elderly patients with intertrochanteric fracture.

FU Shan, the famous doctor of Qing dynasty, had features in diagnosing and treating vomiting. His therapeutic experiences were recorded in his book Fuqingzhu Nvke. From his book we can see that he is treating vomiting basically from kidney and heart, associated by regulating the functions of spleen and stomach, calming the liver and harmonizing somach, and supplementing qi and blood.

Objective To study the best nusing care for postoperative complications of percutaneous coronary intervention. Methods 203 patients with coronary heart disease were selected, evidence- based nursing theory was used to find domestic related literature, looking for the best nursing programs for related complications after percutaneous coronary intervention, and applied to postoperative complications of percutaneous coronary intervention in nursing practice. Results After evidence- based nursing, the prognosis of complications was improved, the hospitalization time was shortened and satisfaction degree of patients was increased. Conclusions Reasonable evidence-based nursing plays an important role in reducing postoperative complications of percutaneous coronary intervention and improving prognosis. Evidence-based nursing care provides a reliable scientific basis for clinical decision- making and meets higher requirements of the patients for nursing care quality and professional compe-tence of nursing staff.

[Summary] The characteristic feature of glucose profiles is high postprandial plasma glucose in Chinese T2DM patients. IDF Guideline recommends that T2DM patients whose postprandial plasma glucose cannot beadequately controlled by oral antidiabetic drugs ,should combine premixed insulin for treatment. Containing 50% insulin formulation for rapid action and 50% that for intermediate action ,mid‐ratio premix insulin analogues show exceptional characteristic of pharmacokinetics ,are able to efficiently improve high postprandial plasma glucose ,and ,with the route of administration flexible and convenience , can enhance patient compliance. Mid‐ratio premix insulin analogues can be one of the optimal option for T2DM treatment.

Objective: To rationally reduce the fees and improve the development of large public hospitals. Methods: Analyze the relationship among the fees, hospital economic activity and medical treatment price mechanism in large public hospitals based on resource dependence theory. Results: Price control can not effectively control the costs. Conclusion: Medical price mechanism reform should in the direction of medical system reform, avoid the “quantity success” in large public hospitals, strive for patients with basic medical health institutions; then it should adequately embodies the value of technical work value of medical project and stimulates the initiative of the doctor.

Cadmium is one of the toxic heavy metals prevalent in the environment.Long-term,even the lowest dose,exposures to this element can damage various organs including the kidney,liver,lung,skeleton,and might elevate the risk of cancer and deformity.The kidney,skeleton and lung are the tissues most affected by chronic cadmium toxicity.The early sign of renal dysfunction,as a main target for chronic cadmium exposure,is tubular dysfunction,and renal failure can be observed in the terminal stage.In recent years,studies about the burden of cadmium in childhood and health damage are gradually increased.Urinary β2-microglobulin,e1-microglobulin and N-acetyl 3-D-glucosamidase have been employed as markers monitoring for the early phase of cadmium exposure and nephrotoxicity.A biomarker named kidney injury molecule-1 aslo has been used for predicting cadmium-induced tubular impairment.It is reported that kidney injury molecule-1 may be more sensitive than traditional biomarkers.

Glucagon-like peptide-1 (GLP-1) receptor agonists are incretin-based drugs for type 2diabetes.In recent years,it has been proven in clinical practices that GLP-1 receptor agonists have protection effect beyond anti-hyperglycemic effects,such as improvement of non-alcoholic fatty liver disease (NAFLD).The cogent evaluation,understanding,and exploration of therapeutic effect and mechanism of GLP-1 receptor agonists in NAFLD are important.Besides,it would be of great significance to identify pathogenesis of diabetes,its correlation with NAFLD,and the development of new drugs.This article briefly reviews the therapeutic effect of GLP-1 receptor agonists on NAFLD.

Herpes simplex keratitis models were created with healthy New Zealand rabbits. During the quiescent period, one group of the rabbits were performed autograft penetrating keratoplasty and another group cross penetrating keratoplasty with noninfeeted rabbits. After removal of the sutures, epinephrine iontophoresis was done for reactivation of the virus, and all the corneal buttons were stained positive of HSV-1 antigens. Transmission electron microscopy revealed signs of viral infection and culture of corneal graft keratoeytes also demonstrated HSV-1 infection, suggesting that the cornea was a site of HSV-1 latency and source of recurrence.

Many clinical trails demonstrated that statin drugs is very effective in the management of atherosclerotic vascular disease,statin drugs can reduce the incidence of the major adverse outcomes of death,heart attack,and stroke.The benefit of statins was due to the lowering of low-density lipoprotein(LDL) cholesterol levels,but there is still much uncertainty in many patient subsets.Nowadays the question is what level of LDL-C is the best for the patients who have a high risk of cardiovascular disease,and how can we do about intensive statin therapy.More evidence is necessary to clarify if current treatment guidelines and low-density lipoprotein cholesterol goals are optimal for all patients within different risk category.

With the clinical application of new technology and immunosuppressive drugs,the early acute graft rejection have been significantly decreased.However,chronic graft failure in long-term transplantation has become one of the most important reasons. As the same as body solid organ transplantation,chronic corneal allograft dysfunction is present after penetrating keratoplasty and has been one of the main reasons of causing repeat keratoplasty.Therefore,studying the mechanism of chronic allograft dysfunction will be of the most important significance in clinical prevention and treatment for chronic graft corneal transplant failure,especially in prolongation of corneal grafts survival rate.