1.Therapeutic effect of naoxintong in treatment of 69 patients with cerebral infarction
Chinese Journal of Primary Medicine and Pharmacy 2011;18(1):46-47
Objective To observe therapeutic effect of naoxintong on the patients with cerebral infarction.Methods 69 patients with cerebral infarction were randomly allocated to naoxintong group or control group. All patients were treated with 20ml shuxuening injection into veins and aspirin 100mg once a day, and those in naoxintong group were treated with naoxinting moreover. Neurological deficit scores (NDS) were evaluated before and after 1 month and 2 months of treatment Results Effective rate and notable effective rate of naoxintong group after 2 months of treatment were 97% and 88% ,obviously higher than those of control group 79% and 52%. Conclusion Nongxintong treatment for cerebral infarction was effective.
2.THE ORIENTATIONAL PROJECTIONS OF SENSORY FIBRES OF MEDIAN NERVE TO THE SUBSTANTIA GELATINOSA OF THE SPINAL CORD IN RATS——AN ACID PHOSPHATASE TECHNIQUE
Songlin HU ; Shengwang HU ; Lixia CAI
Acta Anatomica Sinica 1954;0(02):-
The orientational projections of sensory fibres of median nerve to the Substantia Gelatinosa (SG) of the spinal cord in rats were studied in accordance with the principle of transganglion degeneration by using the acid phosphatase technique. It was found longitudinally that the afferent fibres of the median nerve projected chiefly to SG from the upper part of C_5 to middle part of T_1. In a few rats, projections extended to middle and lower part of C_4 and lower part of T_1. In comparison with the records in anatomy literature and data from researches with HRP technique, a tendency of pre-positioning was noted. The regional projections of the afferent fibres of median nerve were found within the centre line of SG, and mainly in the region of the medial 1/4-1/2 of the medial half. In the segments of C_7-T_1 of a few rats, the whole area of the medial half of SG was projected. In observing the projections of the afferent fibres of median nerve, it was found that they have a tendency of lateralward increase from cranial portion to caudal portion.
3.THE ORIENTATIONAL PROJECTIONS OF SENSORY FIBRES OF RADIAL NERVE AND ULNAR NERVE TO THE SUBSTANTIA GELATINOSA OF THE SPINAL CORD IN RATS——AN ACID PHOSPHATASE TECHNIQUE STUDY
Shengwang HU ; Songlin HU ; Lixia CAI
Acta Anatomica Sinica 1953;0(01):-
The orientational projections of sensory fibres of radial nerve and ulnar nerve to the substantia gelatinosa(SG) of the spinal cord in rats were studied in accordance with the principle of transganglion degeneration by using the acid phosphatase technique.It was found that the affeernt fibers of the radial nerve projected chiefly to SG, from the upper part of C_6 to the middle part of T_1 longitudinally; the ulnar nerves projected chiefly to SG from the middle part of C_6 to the middle part of T_1.In their transverse projections,the afferent fibres of the radial nerve were mainly found in the region of the whole area of the middle 1/3 of SG; and the afferent fibres of ulnar nerve were found within the centre line of SG, and mainly in the region of the lateral 1/2~3/4 at medial half. In summary, radial nerve projected to the lateral region and ulnar nerve to the medial region of SG.
4.THE ORIENTATIONAL PROJECTIONS OF SENSORY FIBRES OF AXILLARY NERVE TO THE SUBSTANTIA GELATINOSA OF THE SPINAL CORD IN RATS——AN ACID PHOSPHATASE TECHNIQUE STUDY
Shengwang HU ; Songlin HU ; Lixia CAI
Acta Anatomica Sinica 1957;0(04):-
The orientational projections of the sensory fibres of axillary nerve to the substantia gelationsa (SG) of the spinal cord in rats were studied in accordance with the principle of transgangionic degeneration by using acid phosphatase technique. It was found that the afferent fibers of the axillary nerve projected chiefly to SG from the upper part of C_6 to the lower part of C_8 longitudinally. In a few rats, projections extended to the lower part of C_5 and upper part of T_1. In comparison with the available studies, a tendency of backward localization was noted. As to their transverse projections, the afferent fibres of the axillary nerve were found outside of the midline of SG, and mainly located in the lateral half of SG, at the 1/3 of median and the 1/3 of interior region. In the segments of C_7C_8 of some rats, the medial. 1/2 of the lateral half of SG was projected. It was found that the projection column from up downward had a tendency of extension toward lateral portion.
5.Ultrasonographic diagnosis of acute superior mesenteric venous thrombosis
Shunping CHEN ; Yuanping HU ; Lixia CHEN
Chinese Journal of Primary Medicine and Pharmacy 2011;18(19):2601-2602
ObjectiveTo investigate the diagnosis of acute superior mesenteric venous thrombosis(MVT) by ultrasonography. MethodsSeventeen patients with MVT were confirmed by operation or CT scanning and followed-up, whose ultrasonographic features were analyzed retrospectively. ResultsUltrasonographic features of seventeen patients with MVT were enlarged superior mesenteric vein filled with hypoecho without flow signals( n =9) ,portal vein and(or) splenic vein filled with hypoecho without flow signals (n =4), intestine wall thickening and intestine distension( n =2) and ascites( n =2). The accuracy of ultrasonographic examination for SMV was 65% (11/17). According to MVT with or without splenic or portal vein involvement,MVT were been classified as two type:large vessel type(n =10) and small vessel type(n =7). The accuracy of ultrasonographic examination for large vessel type and small vessel type were 90% (9/10) and 29% (2/7) ,respectively. Patient with large vessel type of MVT were easy to be diagnosed by ultrasonography than those with small vessel type( x2 =3.41, P < 0. 05 ). ConclusionUltrasonography was valuable in diagnosis of MVT, and it played more important role in diagnosis of large vessel type of MVT.
6.Quantitative Analysis of Five Macroporous Resin Residues
Lixia HU ; Xiaoxian WANG ; Hong ZHANG
China Pharmacist 2015;(3):515-517
Objective:To establish a method for the determination of organic residues ( hexane, benzene, toluene, xylene and sty-rene) in macroporous adsorption resins. Methods:Headspace-GC with a DB-624 column was used to determine the residues in macro-porous resins. The inlet temperature was 200℃ and the FID detector temperature was 240℃. The column temperature programming was as follows:the initial temperature was 40℃, maintained for 3 min, and then raised to 200℃ with the rate of 14℃/min and kept for 2 min. The solvent was methyl alcohol and the carrier gas was nitrogen. HPLC was applied to determine the contents of the five resi-dues. Results:The contents of the five organic residues were all below 20‰ in five macroporous resins in common use including D101, HPD100, AB-8, DM301 and NKA-9. Conclusion:The method is simple,accurate and reproducible. It can be used in the res-idue determination of macroporous resins.
7.Optimization of Water Extraction Technology for Shugan Xiaocuo Granules by Multi-index Comprehensive Evaluation
Lixia HU ; Quanwei YANG ; Hong ZHANG
China Pharmacist 2014;(12):2050-2052,2066
Objective:To study the optimal water extraction method for Shugan Xiaocuo granules. Methods: The study was car-ried out according to the orthogonal tablet. The water amount, extraction time,extraction times and soak time as the influencing factors, and the extractive yield and baicalin content as the indices in a comprehensive evaluation, the optimal extraction technology was screened. Results:The optimal extraction technology was as follows:soaked 30 minutes before cooking, 8-fold water,extracted for 3 times with 1h for every time. Conclusion:The verification test showed that the optimum extraction process was stable,reasonable and feasible.
8.The value of the excursion of diaphragm tested by ultrosonography to predict weaning from mechanical ventilation in ICU patients
Lixia LIU ; Dan SU ; Zhenjie HU
Chinese Journal of Internal Medicine 2017;56(7):495-499
Objective To evaluate the excursion of the diaphragm and analyze the value in predicting weaning from mechanical ventilation in intensive care unit patients.Methods The patients with mechanical ventilation (>48 hours) in ICU at Hebei Forth Medical University Hospital from June 2014 to December were classified into a success group or a failure group according to the weaning outcome.T-piece spontaneous breathing (SBT),airway occlusion pressure at 0.1 sec (P0.1) and maximal inspiratory pressure (MIP),rapid shallow breathing index (RSBI) and P0.1/MIP were measured or calculated.During the period of the 1 st hour SBT,the excursion of diaphragm was measured with ultrasonography.The predictive value of each parameter to weaning was evaluated with ROC curve.Results A total of 98 patients were enrolled in this study,including 74 successfully weaning and 24 failed.There were significant differences between two groups (success group and failure group) in P0.1 [(2.00 ± 2.00) cmH2O (1 cmH2O =0.098 kPa) vs (3.00 ±2.75)cmH2O,P <0.05],RSBI (39.14 ± 16.81 vs 52.00 ± 19.18,P <0.05),left diaphragmatic excursion [(1.12 ± 0.97) cm vs (0.69 ± 1.00) cm,P < 0.001],right diaphragmatic excursion(1.87 ± 0.75) cm vs (1.17 ± 0.76) cm,P < 0.001] and mean value of left and right diaphragmatic excursion [(1.57 ± 0.52) cm vs (0.83 ± 0.53) cm,and P < 0.001].The ventilation time [2.00 (2.00-4.00) d vs 4.00 (2.00-5.00) d],ICU hospital lengths of stay [4.50 (3.00-7.25) d vs 8.50 (6.25-15.25) d] and total hospital lengths of stay [20.00 (15.00-25.25) d vs 25.00 (20.25-37.25)d] were also statistically significant in success group and failure group respectively (all P < 0.05).The cutoff value of diaphragmatic excursion for predicting successful extubation was determined to be 1.14 cm by ROC curve analysis.The sensitivity of diaphragmatic excursion to predict successful weaning was 89.2% and the specificity was 75.0%,the AUCROC was 0.849.Conclusion As an early predictor of diaphragmatic dysfunction,diaphragmatic excursion is probably superior to the traditional parameters in predicting weaning from ventilator in ICU patients.
9.Analysis of clinicopathological characteristics and survival of minority female patients with triple negative breast cancer in Xinjiang Uygur Autonomous Region
Jun HU ; Kexiong WU ; Haipeng ZHU ; Lixia GAO
Cancer Research and Clinic 2011;23(12):836-838
ObjectiveTo analyze the clinicopathologic characteristics and survival of ethnic minority female patients with triple negative breast cancer (TNBC) from Xinjiang Uygur Autonomous Region.Methods The clinicopathological characteristics,including age at diagnosis,size of tumor mass,lymphnode involvement,adjuvant therapy,recurrence of disease and survival of patient,of 48 ethnic minority patient cases with TNBC negative for estrogen receptor (ER),progesterone receptor (PR) and human epidermal growth factor receptor-2 (Her-2) were analyzed,whom were treated in our hospital from January 2001 to December 2005,including age at diagnosis,size of tumor mass,lymph node involvement,adjuvant therapy,recurrence of disease and survival of patients.ResultsOf the 48 patients,median age was 47 years,and 83.3 % (39 cases) of patients had stage Ⅱ or Ⅲ disease.The majority(85.4 %,41 cases)of pathological types were grade Ⅱ or Ⅲ invasive ductal carcinomas,and lymph node involvement was detected in 56.2 % (27 cases) of these patients at initial diagnosis.46 patients were followed and had adjuvant therapy.Tumor-free survival and overall survival at 5 years were 43.5 % (20/46) and 52.2 % (24/46),respectively.Patients with lymph node involved had only 38.5 % (10/46) of overall survival at 5 years.ConclusionThe incidence of triple negative breast cancer of female patients in Xinjiang multiple minority groups is similar to domestic study,and the rates of over all survival is lower than that in Han Chinese patients. The female patients with TNBC in Xinjiang Uygur Autonomous Region multiple minority groups showed higher lymph node involvement at initial diagnosis and more distal metastasis.Patients with lymph node involved had poor survival.
10.Investigation of quality of life and its influencing factors of the patients after liver transplantation
Ying ZHOU ; Yuan LIAO ; Xiaoshun HE ; Xiling HU ; Lixia HUANG
Chinese Journal of Practical Nursing 2009;25(35):15-17
Objective To investigate the quality of life and its influencing factors in hver transplantation recipients in order to supply scientific reference for improving their life quality.Methods 33 patients with terminal liver diseases waiting for liver transplantation(the pre-operation group)and 102 patients 2 weeks after liver transplantation and outpatients for follow-up visits(the post-operation group)were conducted with SF-36,self-rating anxiety scale,self-rating depression scale,and social support questionnaire.Results Except for the scores of physiological function,emotional role,social function in SF-36.differences of scores of other factors were evident between the preand post-operation groups.Life quality of patients over 1 year after operation was better than those within 1 year. The influencing factors of QOL were subjective support and anxiety.Conclusions After liver transplantation,the patients' QOL evidently improves.Life quality of patients over 1 year after operation was better than those within 1 year.Patients' QOL is positively related to subjective support,negatively related to anxiety.