1.Study on the correlation between electrocardiogram and serum enzyme and electrolyte in patients with primary liver cancer
Lixia ZHANG ; Shuanghua PAN ; Yingping HE
Practical Oncology Journal 2016;30(6):523-526
Objective To investigate the relationship between electrocardiogram and serum alanine ami-notransferase and electrolytes in patients with primary liver cancer .Methods Clinical data of 241 patients with primary liver cancer treated in our hospital were retrospectively studied .Single factor analysis was used to analyze the risk factors of abnormal electrocardiogram in patients with primary liver cancer .The multivariate logistic re-gression analysis was performed to analyze the factors that were statistically significant .Results Single factor a-nalysis showed that age,gamma glutamyl transferase(GGT),electrolyte is associated with ECG abnormalities in the patients with primary hepatocellular carcinoma (P<0.05).Multivariate logistic regression analysis showed that,the GGT and electrolyte anomaly led to primary hepatocellular carcinoma in the patients with abnormal ECG independent risk factors .Conclusion The level of electrolyte ,age≥60 and GGT anomaly and primary electro-cardiogram in patients with hepatocellular carcinoma ( HCC ) is a close relationship for active hepatoprotective , maintain electrolyte balance therapeutic intervention for patients with hepatocellular carcinoma ( HCC) .
2.A Study on the Ratio of T_H1, T_H2 Cell in the Peripheral Blood from Patients with Severe Pregnancy Induced Hypertension
Xiuxia WANG ; Lixia HE ; Lurong QU
Chinese Journal of Perinatal Medicine 1998;0(03):-
Objective To investigate the immunologic etiology of pregnancy induced hypertention (PIH)by studying the changes of T H1 and T H2 cell ratio in the peripheral blood from patients with severe PIH. Methods We examined the cell percentage of T H1 cell(secreting cytokine IFN ?) and T H2 cell(secreting cytokine IL 4),which were from CD4 positive, by flow cytometry tri stained with PerCP CD4,FITC IFN ? and PE IL 4 monoclonal antibody. The blood samples were from severe PIH patients and normal third trimester patients. Results The percentage of T H1 cell 38.01?9 04% from the peripheral blood of severe PIH partuients was significantly higher than that of the normal partuients of the third trimester 30.26?8.65%, while the percentage of T H2 cell 2.25? 0.61% was much lower P
3.Domestic Application of Ion Chromatography in Quality Control of Chemical Drugs
Zhaoxia LIU ; Lan HE ; Lixia DING
China Pharmacist 2016;19(5):966-969
Ion chromatography(IC)can make up the deficiency of LC or GC for the analysis of ionic drugs because of the unique separation mechanism,so IC is more and more widely applied in the field of drug analysis. In the paper,the application of IC is reviewed in the quality control of chemical drugs.
4.Congenital hypertrophic pyloric stenosis associated with intestinal malrotation in infants:clinical characteristics
Zhibin NIU ; Lixia HE ; Yong LI
Chinese Pediatric Emergency Medicine 2011;18(6):531-532
Objective To investigate the clinical characteristics and management of congenital hypertrophic pyloric stenosis (CHPS) associated with intestinal malrotation (IM) in infants.Methods The clinical data of 6 cases with CHPS and IM admitted in our hospital from Jan 2003 to Dec 2009 were reviewed,including clinical presentation,symptoms and information of imageology.Results Through barium meal examination and sonography,4 cases were diagnosed CHPS and IM,pyloromyotomy and Ladd's procedure were performed;two cases were diagnosed CHPS,only pyloromyotomy was done,secondary operation was performed for recrudescence of vomiting.All the cases were followed up for 1 to 3 years with good prognosis.Conclusion The etiology of CHPS with IM isn't clear.The diagnosis of IM may be delayed because the symptoms of IM can be masked by that of CHPS.It is helpful for diagnosis of this disease to have barium meal and sonography examination.Good prognosis will be achieved if prompt preoperative diagnosis and operation can be done.
5.Performance-based compensation management system at a public hospital in Wuhu
Sizhong HE ; Lixia SUN ; Huaihong WANG ; Annan HE ; Qi LI
Chinese Journal of Hospital Administration 2013;29(10):724-726
Reasonable and effective compensation and incentive mechanism is key to maintaining and stimulating incentives of the staff.By means of defining the main problems and defects in the current hospital compensation system in China,performance management is used as the cornerstone for designing the public hospital compensation and incentive mechanism.Resource-based relative value scale(RBRVS) assessment system is called into play to build a compensation management system,which features workload as the basis,technical competency and risk assessment as the reference and balance scorecard as the means.This can build a fair,scientific and reasonable salary distribution system and performance evaluation system,which maximize incentives of the compensation system,and in the end maximize the economic and social benefits of the hospital.
6.Influence of Roy adaptation mode and resistance training on cardiac function and life quality of patients with chronic heart failure
Suqin CHEN ; Congcong LAI ; Lixia LIAO ; Runwen HE
Modern Clinical Nursing 2015;(8):35-38
Objective To explore the influence of Roy adaptation mode and resistance training on cardiac function and life quality of patients with chronic heart failure. Methods One hundred patients with chronic heart failure in our hospital cardiovascular department were enrolled in the study. All patients received conventional treatment of chronic heart failure. They were equally divided into the control group and the observation group using random digit grouping method. The control group received conventional nursing mode and observation group received Roy adaptation mode joint resistance training. The cardiac function and life quality of two groups were compared after two months. Result After three months′intervention, each index of cardiac function was significantly better than that of the control group ( P < 0 . 01 ) , 6 minutes waking distance of the observation group was significantly longer than that of the control group ( P < 0 . 01 ) , and the life quality score was significantly higher than that of the control group (P<0.01). Conclusion The Roy adaption mode and resistance training can improve heart function and the overall quality of life of the patients with chronic heart failure.
7.Clinical Efficacy of Calium Dobesilate Combined with Valsartan to Reduce Proteinuria of IgA Nephropathy
Min LIU ; Lixia DAI ; Xiaochun ZHANG ; Xiaodong HE
China Pharmacist 2014;(2):247-249
Objective:To observe the clinical efficacy of calcium dobesilate combined with valsartan in the treatment of IgA ne-phropathy. Methods:Totally 58 cases of IgA nephropathy were randomly divided into the treatment group and the control group. The control group enrolled 29 cases given valsartan 160 mg · d-1 . The treatment group included 29 cases treated with calcium dobesilate 500 mg·time-1 ,tid,and valsartan 160 mg·d-1 . After 6 months, the following indicators were observed, such as blood pressure,fi-brinogen,urea nitrogen,serum creatinine,blood uric acid,and 24-hour urinary ( Upro) . Results: After 6 months, UA and Upro of the two groups were significantly declined than those before the treatment(the control group P<0. 05,the treatment group P<0. 01). Upro of the treatment group was declined from (1. 48 ± 0. 84) g/24h to (0. 41 ± 0. 22) g/24h,and there was statistical significance com-pared with the control group (P<0.05). BUN, Scr and FIB were decreased significantly(P <0.05),while no significant change showed in those in the control group after the treatment. Conclusion:Calcium dobesilate combined valsartan can effectively reduce Up-ro and improve renal function in IgA nephropathy.
8.Constructing autologous composite skin around the expander for the repair of skin defects
Jianxiong AI ; Lixia HE ; Renhuan YANG ; Zumeng YA
Chinese Journal of Tissue Engineering Research 2014;(20):3139-3143
BACKGROUND:The construction of tissue engineered skin needs a long time and high price, and the repair effects are poor. Moreover, the problems such as antigen elimination and disease propagation are not thoroughly solved. How to solve the tough problem of wound surface repair in patients lacking of autologous skin using current mature technology before the occurrence of ideal tissue engineered skin.
OBJECTIVE:To investigate the effects of autologous composite skin constructed around expanders on the repair of the wound surface.
METHODS:A total of 10 rabbits were selected. Two globular silica gel expanders were embedded subcutaneously in the symmetrical sites on the back of rabbits. After the expanders were covered by fiber kystis, cellsuspension of primary cultured skin epithelial cells (experimental group) or physiological saline (control group) were infused into lacuna between the expander. Four weeks later, the expanders were obtained. Experimental group presented epithelization, i.e., autologous composite skin. The skin and some fiber members on the top of the expanders were resected around the encystations. The fiber kystis on the bottom and surrounding the expanders was left to form the wound surface covered by autologous composite skin. However, the wound surface was covered by non-epithelization fiber kystis in the control group. The healing of wound surface was observed until recovered.
RESULTS AND CONCLUSION:In the experimental group, the wound surface was ruddy and pure, with less secretion;the average healing time was (14.0±0.4) days;the microscopic appearance indicated that epithelial layer was thick and regular. In the control group, there was more secretion on wound surface;the average healing time was (27.0±0.7) days;the microscopic appearance indicated that epithelial layer was thin and irregular. These results suggested that the construction of autologous composite skin around the expanders could noticeably promote the healing of wound surface.
9.The compliance and impact factors of prenatal check for pregnant women
Lixia YANG ; Xiaoyang WANG ; Bing HE ; Yufeng ZHOU
Chinese Journal of Practical Nursing 2008;24(24):61-64
Objective Through the investigation of the compliance and impact factors of prenatal check to the pregnant women,we aimed to supply the ideas and methods to improve antenatal care compliance. Methods This investigation used the questionnaire which was designed by the author to survey 100 pregnant women in class three level hospital in Guangzhou.The results underwent subsequent analysis. Results There were 68.4%of the pregnant women didn't finish the check.The average check times Wag only five.70.4%of them who were younger than 30 hadn't fulfilled seizure frequency rates,while 65.9%for who were older than 30(P>0.05).The pregnant women with school-age≤9 and school-age>9 who hadn't fulfilled seizure frequency rates were 83.3%and 50.0%.Irregular check rates were 59.3%、29.5%(P<0.01).The floating population and the local population in the area of prenatal compliance results showed statistical difference.P<0.01.The family whose income was higher than 3000 yuan per-month were better than those lower than 3000 yuan per-month about the antenatal check compliance(P<0.05).More than 70% of pregnant women felt risk factors of pregnancy complications,their partners' support,local medical conditions and attitudes of medical staff had influence of their antenatal check compliance.Conclusions The compliance of the low education and low family income group is relatively low.For the affecting factors.how to improve the prenatal check compliance of such crowd is worthy of further study.
10.Pulmonary Diffusing Capacity and BALF Lymphocyte Phenotype in Sarcoidosis
Xiaolin HE ; Zhi LIU ; Lixia HUANG ; Zhenhua LI ; Runjiang YU
Journal of China Medical University 2001;30(2):130-132
Objective: Our aim was to study whether the cellular bronchoalveolar lavage fluid (BALF) profile was associated with the parameters of pulmonary function tests. Methods:Lung function tests and BAL were carried out in 18 untreated, non-smoking patients suffering from sarcoidosis and 18 normal subjects. Results:(1)Lung function tests were normal at rest in patients with sarcoidosis(P>0.05), the single breath carbon monoxide diffusing capacity decreased (P<0.05),and the small airway function decreased too (P<0.05).(2)The percentage of lymphocytes in BALF of sarcoidosis increased comparing with the normal subjects(P<0.01),and the ratio of CD+4 to CD+8 in BALF increased significantly in sarcoidosis(P <0.05), furthermore, the increase of both the percentage of lymphocytes and the ratio of CD+4 to CD+8 in BALF of sarcoidosis were well nagatively correlated with the decrease of the percentage of DLCO (r=-0.67, P<0.01 and r=-0.55, P<0.05, respectively), the decrease of mid-expiratory flow at 50% of vital capacity (FEF50%) was well correlated with the increase of the percentage of lymphocytes in BALF of sarcoidosis (r=-0.54, P<0.05). Conclusion:Pulmonary diffusing capacity(DLCO) was significently correlated with BALF lymphocyte phenotype,so was small airway function,and can act as the marker of activity of sarcoidosis.