Objective: To study the stability of forsythiaside. Methods: The stability of forsythiaside was studied by using UV spectrum obsiving the changes of spectrums in different conditions. Results: Forsythiaside was very unstable under the condition of alkali (pH=9.40), relatively stable at the pH=6.86, 60?Cand stable at the pH= 4.03 . Conclusion: The stability of forsythiaside can be affected by the condition of the acid, alkali and temperatures obviously.

Objective To study the changes of the mood states at different time point of one-time exhaustive exercise.Methods16 participants were tested by POMS at the moments before,at,after recovery and after recovery 20 min of one-time exhaustive exercise.Results The scores of the 7 subscales got by 4 measures were used for one-way repeated measures analysis of variance.The results were showed that tension subscale scores (F (3.45) =0.335,P＞0.05,ES =0.022),anger subscale scores (F(3.45) =3.683,P＞0.05,ES =0.197),fatigue subscale scores (F(3.45 =0.863,P＞0.05,ES =0.054),depression subscale scores (F(3.45) =1.905,P＞ 0.05,ES =0.113 ),confusion subscale scores (F( 3.45) =0.601,P ＞ 0.05,ES =0.039 ) and self-esteem subscale scores (F(3.45) =2.804,P ＞ 0.05,ES =0.157 ) had no significant differences,but vigor subscale scores increased significantly (F(3.45) =8.778,P ＜ 0.01,ES =0.369).Conclusion One-time exhaustive exercises enhanced individual' s positive mood states.

This article discussed the necessity and method of setting up a comparative imaging medicine course, which is considered to be valuable for the future development and creativity of graduate students majored in nuclear medicine and imaging medicine.

Objective To explore the effect of nasal continuous positive airway pressure ventilation on severe respiratory disease and hypoxaemia. Methods In 30 neonates with severe respiratory disease-induced hypoxemia were managed with nasal continuous positive airway pressure, and corresponding nursing. Nasal continuous positive airway pressure before and after treatment, 24h arterial partial pressure of oxygen (PaO2), partial pressure of carbon dioxide (PCO2), PaO2/FiO2 and pH value in children were observed. Result After nasal continuous positive airway pressure ventilation, the levels of PaO2, post-PCO2, PaO2/FiO2 and pH value of children were better than the positive pressure ventilation before treatment and positive pressure ventilation (P < 0.05). Conclusions Nasal continuous positive airway pressure ventilation has good therapeutic effect on severe respiratory disease in children with neonatal hypoxemia. Good ventilation pressure regulation, skin and mucosa protection, prevention of vomiting in children with nursing to ensure the positive significance of continuous positive airway pressure therapy.

This article aims to study the present condition and disadvantages of current obstetrics and gynecology teaching and discuss the urgent needs and methods of evidence-based medicine (EBM) introduction to it.

The aim of the study is to investigate the effects of concentration, intestinal segments, pH, inhibitors of proteins (P-gp), Na(+)-dependent glucose transporter (SGLT1) on the intestinal absorption of berberine, and to compare intestinal absorption of berberine in combinations. With phenol red as the indicator, in situ single pass intestinal perfusion (SPIP) model was used and intestinal absorption of pure berberine at concentrations of 36.70, 46.17 and 92.33 microg x mL(-1), simulated system of HLJDT (mixture of berberine, baicalin and geniposide), HLJDT with the concentration of berberine 92.33 microg x mL(-1) in perfusion solution of different intestinal segments (duodenum, jejunum, ileum, and colon) were determined by HPLC in combination with diode array detection (DAD). The results indicated that Ka values ofberberine at different concentrations had little significant difference among that obtained after perfusing via duodenum, jejunum, ileum and colon indicating that the absorption of berberine was mainly the passive diffusion. It was also suggested that SGLT1 and P-gp might exert some effects on the absorption of berberine. Ka and Peff values of berberine in a mixture of pure compounds and HLJDT for different intestine segments of rat showed an increasing tendency and was significantly different (P < 0.05) indicating that berberine in a mixture of pure compounds and HLJDT was assimilated better in small intestine. These results indicate that the intestinal absorption of berberine may be affected by compatibility of compounds. Additionally, berberine has wide absorption window and better absorption in colon.

ObjectiveTo explore the relationship among resilience,attribution,and coping style for freshmen.Methods 977 freshmen were surveyed with Connor-Davidson Resilience Scale,Multidimensional-Multiattributional Causality Scale,and Simplified Coping Style Questionnaire,then compared different freshmen's resilience,attribution,and coping style,and analyzed their relationship.ResultsThe city freshmen showed significant higher resilience(68.88 ± 10.57 ),academic external attribution (21.14 ± 6.01 ),and interpersonal external attribution ( 22.87 ± 6.42 ) than rural freshmen ( ( 67.51 ± 10.43 ),( 19.81 ± 5.88 ),( 21.86 ± 5.88 ) respectively,t =2.03,3.48,2.57).Vocational freshmen showed significant higher academic internal attribution ( 28.68 ± 5.30 )and interpersonal internal attribution (26.81 ± 5.82) than undergraduate freshmen ( ( 27.61 ± 5.47 ),( 25.53 ±5.92),t =3.00,3.30).The only children showed significant higher resilience ( 68.88 ± 10.81 ) and academic failure luck (4.37 ± 2.21 ) than those having siblings ( (67.44 ± 10.18 ),(3.96 ± 2.12 ),t =2.15,3.02 ).Positive coping style,ncgative coping stylc,academic failure external attribution,academic success internal attribution,residence,and academic failure internal attribution had significant direct influence on resilience(β =16.435,- 4.919,- 0.344,0.308,1.396,- 0.182).ConclusionPositive coping styles and reasonable academic attribution can effectively predict great resilience of freshmen.

The expression of nm23-H1 and p53 genes were studied with ABC immunohistochemical method in 54 cases of gastric cancer and 57 cases of colorectal cancer. The result showed that the expression of nm23-H1 was 72.2% in gastric cancer and 64.9% in colorectal cancer, respectively. No significant difference was found between the expression of this gene and lymph node metastasis of the cancers. The mutant p53 protein expression was 53.7% and 52.6% in gastric and colorectal cancers, respectively. Although it was not correlated with lymph node metastasis, its expression was significantly higher in cancers with distant metastases, suggesting that the mutant p53 protein expression may be indicative of poor prognosis in gastrointestinal cancers.

Nowadays, lung cancer has become one of the most common malignant tumors. The animal models of lung cancer have played very important role in the research on the etiology, diagnosis and treatment of human lung cancers. According to the preparation method, the animal models of lung cancer can be divided into spontaneous, induced, transplanted and transgenic models. The transplanted animal models are most commonly used. Transplanted animal models can be classified into heterotopic transplantation model and orthotopic transplantation model, each has its own characteristics. This article aims to introduce the research progress of transplanted animal models of lung cancer in recent years, focusing on the establishment of animal model, the improvement of preparation of animal model, the application of imaging in vivo in evaluating the animal model, the use of transplanted animal model in the study of interventional therapy, etc.

Gallbladder cancer is a highly malignant tumor of the digestive tract with a poor prognosis. Currently, only radical surgical resection can achieve good results. As an important part of tumor adjuvant treatment and palliative treatment, radiotherapy has been widely used in the treatment of various malignant tumors and achieved certain effect. This article mainly reviews advances of radiotherapy in gallbladder cancer from four aspects: postoperative radiotherapy, preoperative neoadjuvant radiotherapy, intraoperative radiotherapy and palliative radiotherapy for gallbladder cancer.