Objective To observe the shenqifuzheng injection (SFI) combined with PG therapy (gemcitabine and cisplatin) in patients with non-small cell lung cancer (NSCLC). Method 76 patients with NSCLC were selected from August 2011 to August 2013 and randomly divided into observation group and control group. Each group had 38 cases. The control group received gemcitabine and cisplatin, observation group were gave SFI on the basis of control group. The total efficiency, disease control rate, quality of life and incidence of adverse reactions were observed after treatment in each group. Results The total effective rate was 47.37%in observation group , 42.11%in control group, there was no significant difference between two groups. The disease control rate in observation group was 81.58%higher than 57.89%in control group, the difference was statistically significant (χ2=3.990, P<0.05). The improvement rate in quality of life was 60.53%in observation group better than 31.58%in the control group , the difference was statistically significant (χ2=5.296, P<0.05).The decrease incidence of white blood cell (χ2=4.491, P<0.05) and platelets (χ2=4.491, P<0.05) in observation group were significantly lower compared with the control group, while, there were no difference of liver damage and gastrointestinal reactions between two groups. Conclusion SFI is helpful to improve the efficacy of PG therapy in patients with NSCLC and relieve the side effects of chemotherapy.

Objective: To study the antitumor activity and immune modulation of extract from Chlorella pyrenoidosa Chick. (CE). Methods:Cyclophosphamide is positive control and saline is negative control. S180-bearing and HCA-bearing mice were used as animal model. The changes of the growth of S180 and HCA tumor cells in vitro, the changes of tumor weight in vivo and the effect on immune system such as phagocytosis of macrophages,proliferation of lymphocytes were investigated when CE were used. Results: The tumor cells were killed by CE in vitro. CE inhibited tumor growth markedly in S180 and HCA bearing mice and the effect was enhaced if CE and cyclophosphamide were used simultaneously. CE also enhanced the immune function. Conclusion: CE has the antitumor effect and the effect of immune modulation.