1.Readout of the Guideline for the Management of Thyroid Disease in China
Chinese Journal of Practical Internal Medicine 2003;0(01):-
The second part of (2008 edition)includes iodine deficiency disease,thyroditis and thyroid nodule.This guideline reaffirms the epidemic characteristics,the prevention and the management of iodine deficiency disease.It identifies the measurement of iodine nutritional status and the necessity of iodinized salt.It emphasizes the regular diagnosis and treatment of subacute and chronic thyroiditis,and also mentions the advancement on differential diagnosis and rational therapy of thyroid nodules.In addition,it gives some advices on the management of thyroid nodules in two special groups(pregnant women and children).
2.Treatment for the relapsed or refractory severe aplastic anaemia
International Journal of Pediatrics 2017;44(5):339-343
Severe aplastic anaemia is a marrow failure syndrome characterized by pancytopenia and hypocellular bone marrow.Immunosuppressive therapy(IST)consisting of antithymocyte or antilymphocyte globulin (ATG) and cyclosporine has been recommended for children lacking HLA-matched sibling donor.For children unresponsive to initial immunosuppressive therapy or those who relapsed after first immunosuppressive therapy,they can choose repeat course of immunosuppressive therapy,allogeneic hernatopoietic stem cell transplantation,new drugs or clinical trials.And the prognosis has been greatly improved in recent years,dueing to the development of allogeneic hematopoietic stem cell transplantation and the application of new drugs such as eltrombopag.This article reviews researches advance in different therapies for children with relapsed or refractory severe aplastic anaemia,aimed at guaiding treatment methods.
3.Update on the treatment of thyroid-associated ophthalmopathy with glucocorticoid
Chinese Journal of Endocrinology and Metabolism 2000;0(06):-
Thyroid-associated ophthalmopathy(TAO)is an organ specific autoimmune disorder affecting the life quality of patients.Glucocorticoids have been applied for many years in the treatment of TAO,though the side effects are the major concern.Recently,intravenous methylprednisolone pulse therapy is a novel and effective method for TAO treatment.Nevertheless this new strategy needs to be modified,and attention should be paid to the indications and contraindications in order to prevent liver damage when high dose methylprednisolone is applied.
4.TOTAL MESORECTAL EXCISION FOR RECTAL CANCER
Chinese Journal of Bases and Clinics in General Surgery 2001;8(1):54-55
Objective To introduce the surgical technique and results of total mesorectal excision (TME) for rectal cancer. Methods Reviews.Results As a result of TME, local recurrence rates have declined from 20%-30% to 3%-8%, 5-year survival rate have risen to 75%, and the rates of sphincter preservation have risen too.Conclusion Total mesorectal excision reduces the local recurrence rates and raise the survival figures after excision of rectal cancer. Patients have a high quality of life.
5.Carrying out clinical teaching for foreign interns according to their charateristics
Chinese Journal of Medical Education Research 2006;0(12):-
Taking the characteristics of Indian students into account,teaching quality can be improved by these means:thorough preparation before class,various application for teaching,mutual and interactive communication and inspiration.
6.Caloric restriction and control of body weight
Chinese Journal of Endocrinology and Metabolism 2014;30(2):160-162
Control of body weight is a hot topic.It is considered as the cornerstone for the management of patients with obesity and type 2 diabetes based on the effect of improving blood glucose,lipid profile,blood pressure,and insulin sensitivity.The strategies for weight loss include diet restriction,exercise,medicine,and bariatric surgery.In the present article the relationship between caloric restriction and weight loss was reviewed,focusing on the hot topics as to what extent weight loss could be achieved,the maintenance of ideal body weight,the risk factor of weight regain,and weight loss in particulas populations like obese children,adolescents,and older adults.
7.Combined use of mosapride and polyethylene glycol for colonoscopy preparation
Chinese Journal of Digestive Endoscopy 2012;23(1):32-35
Objective To compare the clearing effect between combination use of mosapride and polyethylene glycol (PEG) and polyethylene glycol only for colonoscopy preparation of patients with constipation caused by functional diseases.Methods A total of 212 adult patients who underwent colonoscopy examination were recruited to this randomized single blinded controlled study.Patients in control group received 3 liters of PEG only,whereas patients of experimental group received 10mg mosapride 30min before 3liter PEG.The patients were surveyed for the tendency of constipation.Experimental variables including time of first defecation and completion of bowel cleansing,defecation frequency,and degree of discomfort during colonoscopy preparation were recorded.Results The times of first defecation and completion of bowel cleansing of experimental group were shorter than those of control group ( P < 0.05 ),but there were no significant differences in defecation frequency,the degree of discomfort and the bowel cleansing quality between 2 groups ( P > 0.05 ).The percentages of patients with constipation in control and experimental groups were 26.61% and 26.67%,respectively.The defecation frequency and the degree of discomfort of constipative patients were similar in both groups ( P > 0.05 ).The time of first defecation and time of completion of bowel cleansing of constipative patients in experimental group were shorter than those in control group ( P < 0.05 ).The bowel cleansing quality of constipative patients in experimental group was better than that of control group ( P < 0.05 ).There was no difference in defecation frequency and adverse reaction between 2 groups (P < 0.05).Conclusion Combination of mosapride and PEG for colonoscopy preparations of patients with functional constipation tends to shorten times of first defecation and completion of bowel cleansing,and to increase the bowel cleansing quality.
8.Effects of EGF and bFGF on wound healing after penetrating keratic autoplasy in rabbits
Journal of Third Military Medical University 2001;23(2):211-214
Objective To observe the effects of epithelial growth factor (EGF) and basic fibroblast growth factor (bFGF) on wound healing of the penetration keratoplasty (PKP) with autograft in rabbits. Methods After the establishment of penetrating keratic autograft model on 24 rabbits, they were equally divided into EGF-, bFGF-, EGF+bFGF-treated and control groups. The wound healing of all the animals were observed with healing intensity, liquid scintillation counter, AgNORs staining, VG staining and transmission electron microscopy. Results ①EGF, bFGF, and EGF+bFGF increased the limiting pressure of the wounds and the 3H-TdR incorporation. ②The fibroblast cells and its secreting proliferative collagen in both the bFGF group and EGF+bFGF group were more well-arranged. Conclusion ①EGF, bFGF, EGF+bFGF can obviously elevate the intensity of wound healing after PKP and enhance the synthesis of DNA. ②The effect of this agent combination is just as the same as bFGF applied alone 14 d after the operation. ③bFGF can improve the quality of wound healing after PKP.
9.New insight into caloric restriction therapy
Chinese Journal of Endocrinology and Metabolism 2013;(4):269-272
Caloric restriction has been practiced over 500 years as a method for increasing both the length and quality of life.Experimental work confirming the success of this approac h in animals has accumulated in the last 100 years.Since 2000,emerging evidence in humans has shown that caloric restriction can delay the onset of age related diseases including reduced risk of obesity,diabetes,cardiovascular disease,cancer,and neurodegenerative disorders.The mechanisms and clinical applications have been extensively studied.
10.Hashimoto's thyroiditis and papillary thyroid cancer: causality or contingency?
Chinese Journal of Endocrinology and Metabolism 2013;29(12):1006-1009
The link between Hashimoto's thyroiditis(HT) and papillary thyroid cancer(PTC) has long been a topic of controversy.Some authors suggested that these two disorders are positively correlated,whereas others reported no relationship.Here we summarized the studies made in investigating the correlation between HT and PTC,and analyzed the nature of the correlation between HT and PTC based on biomolecular mechanisms.