1.Long-term result and prognostic analysis of 18FDG PET/CT positioning three-dimensional conformal radiotherapy for stage Ⅲ non-small cell lung cancer
Baozhi REN ; Lisong ZHONG ; Qianshi ZHANG ; Jianjun YUAN ; Xing TAO
Chinese Journal of Radiation Oncology 2010;19(6):500-503
Objective To analyse the long-term result and prognosis of 18 FDG PET/CT positioning three - dimensional conformal radiotherapy ( 3 DCRT ) for stage Ⅲ non - small cell lung cancer. Methods Sixty-four cases with stage Ⅲ non-small cell lung cancer (clinical stage Ⅲa- Ⅲb ) were randomly divided into two groups: PET/CT positioning three-dimensional conformal radiotherapy group (PET/CT group) and the conventional CT positioning three-dimensional conformal radiotherapy group (conventional CT group). In the PET/CT group, the target volume and critical organs were sketched according to PET/CT after fusion of the PET and the CT images; the treatment plan was worked out, then conventional fractionated 3DCRT ( total dosage around 40 Gy) followed by field-shrinked radiotherapy to a total dose of 65 Gy or sowas performed ;in the conventional CT group, the target volume and critical organs were sketched according to CT and 3DCRT were performed to the same total dose; All cases were treated with the TP scheme (paclitaxel 175 mg/m2,d1 ,cisplatin 40 mg,d2-4) adjuvant chemotherapy for 6 cycles after the radiotherapy. Results The followup rate was 100%. The number of patients who completed the 1-,2-and 5-year follow-up were 40,20 and 11 respectively ;The number of patients of the PET/CT group and conventional CT group were 23 and 17,11 and 9,7 and 4 respectively. Target volumes of 13 cases in the PET/CT group were changed. The complete remission and partial remission rates of the two groups were 13% 、66% and 19% 、53% (x2 = 0. 33, P =0. 564), respectively. The 1-,2-and 3-year local control rates of the PET/CT group and conventional CT group were84 % 、66% 、53 % an d72% 、59% 、44% ( x2 = 2.36, P = 0. 124 ) respectively. The1 -, 2-and 3-year survival rates were 72% 、34% 、22% and 53% 、28% 、13% (x2 =2. 46,P =0. 117) respectively. The level-1 and level-2 lungs' and trachea's late radiation injury of the PET/CT group and the conventional CT group were 28% and 53% ( x2 = 4. 14, P = 0. 042 ), respectively. The hilar and mediastinal lymph node recurrence rates of the PET/CT group were lower than those of the conventional CT group, were 3% ,25%(P = 0. 026) and 6%, 28% ( P = 0. 042 ), respectively. The main reason for treatment failure was distant metastasis both in the PET/CT group and conventional CT group,56% and 47% (x2 = 0. 56,P = 0. 453 ),respectively. Conclusions PET/CT, as a method of sketching the target of stage Ⅲ non-small cell lung cancer, can improve the radiation treatment plan, reduce the recurrence rate of hilar and mediastinal lymph nodes, meanwhile it can not improve the long-term survival rate; Distant metastasis was the main reason of failure.
2.Effects of self-made mold in the spreading moxibustion of patients in the Department of Spine Orthopedics
Lisong MA ; Chunfeng LIANG ; Qi ZHONG ; Jue FENG ; Aijin WEI ; Fengmei LAN
Chinese Journal of Modern Nursing 2021;27(27):3753-3755
Objective:To explore the effect of self-made mold in the spreading moxibustion of patients in the Department of Spine Orthopedics.Methods:From January 2019 to September 2020, convenience sampling was used to select 160 patients with spreading moxibustion in the Department of Spine Orthopedics of Liuzhou Traditional Chinese Medicine Hospital as the research objects. According to the order of treatment, patients were randomly divided into the control group and the experimental group, with 80 cases in each group. The control group used conventional methods for spreading moxibustion, and the experimental group used self-made molds for spreading moxibustion. The ginger column cracking of the two groups of patients, and operation time of 6 operators for spreading moxibustion on the two groups of patients was compared.Results:The cracking rate of ginger columns in the experimental group was lower than that in the control group, and the difference was statistically significant ( P<0.01) . The operation time of the 6 operators on the patients in the experimental group was (2.5±0.23) min, which was shorter than (18.5±0.41) min in the control group, and the difference was statistically significant ( P<0.01) . Conclusions:The application of self-made molds can shorten the spreading moxibustion operating time of operators and reduce the cracking rate of ginger columns, which is worthy of clinical application.