Scientific design of the teaching content of medical ethics is a crucial element in achieving satisfying educational effect of medical ethics,making it more consistent with the developing tendency of diversity in majors and arrangement of medical colleges,better solving the conflict between the limitations of teaching time span and the diversity of teaching content,promoting teaching effects,and contributing the all-round development of medical students.

Ethical issues have been the kind of problems that we have to face in medical research.The article,from the perspective of ethical problems in medical research,on the basis of analyzing the reasons and harms of the problem,puts forward the following strategies,such as,strengthen ethical consciousness of the medical scientific research personnel,reinforce ethical responsibility of the medical scientific research personnel,play the role of supervision by the ethical review,improve the scientific management system and system construction.In order to realize the medical purpose,we must put heart and soul into for the people the mental and physical health services.

With the rapid development of modern medicine,the particularity of medical and health industry becomes more and more prominent.It has increased the public' strong appeal about medical works' reverencing life.On the ethical implication of reverencing life as the breakthrough point,the article elaborated the basic contents of medical students'ethical education about reverencing life,and strive to explore a multi-channel,three-dimensional,all-round education path.

As an important subject of higher medical education,medical ethics has its unique theoretical system and teaching pattern of education and teaching.A scientific planning of the teaching content of medical ethics is a key component in improving teaching effect,promoting students' moral,intellectual,physical and aesthetical development for being high quality medical talents,and better realizing the teaching target of medical ethics.

BACKGROUND:There are many experimental studies about compression mechanics of femur after hip replacement at home and aboard. Therefore, it is very important to study the torque, torsion angle, load-displacement relationship of femur after hip replacement. Comparing and analyzing the properties of compression and torsional mechanics of traditional-type prosthesis and anatomical-type prosthesis is of important significance for studying hip replacement and the stability of artificial prosthesis.
OBJECTIVE:To compare and analyze the stability of traditional-type prosthesis and anatomical-type prosthesis by stimulating femoral axial compression and torsion tests after hip replacement, so as to provide biomechanical parameters for clinic practice.
METHODS: Twelve specimens of left- and/or right-side femur were selected. The femoral necks of 6 left-side femur specimens were retained as the anatomical-type titanium artificial joint prosthesis group, and the femoral necks of the 6 right-side femur specimens were removed as the traditional-type cobalt-chromium-molybdenum artificial joint prosthesis group. The femur specimens in these two groups were respectively placed onto the electronic universal testing machine workbench and were imposed compression stress at the experimental velocity of 5 mm/min. The corresponding displacement values were read under the force of 20, 40, 60, 80 and 100 N. And then, both ends of the femur specimens from these two groups were placed within the chuck of torsion testing machine, and were imposed torque at the experimental velocity of 1(°)/s. The corresponding torsion angle values were read under the torque force of 5, 10, 15 and 20 N?m.
RESULTS AND CONCLUSION: Under the external force of 100 N, the displacement was (2.03±0.06) mm in the traditional-type prosthesis group, and (1.83±0.05) mm in the anatomical-type prosthesis group. Under the torque force of 20 N?m, the torsion angle values of traditional-type prosthesis was (21.7±0.7)°, and that of anatomical-type prosthesis was (13.2±0.4)°. The displacement under the external force of 100 N and the torsion angle values under the torque force of 20 N?m in the anatomical-type prosthesis group were al significantly less than those in the traditional-type prosthesis group (P < 0.05). These results suggest that traditional-type and anatomical-type prostheses have different compression and torsion mechanical properties. The anatomical-type femur prosthesis has a better stability than traditional-type femur prosthesis.

Objective To investigate the effect of suppression of ischemia induced retinal neovascularization by VEGF antisense oligodeoxyribonucleotides. [WT5”HZ]Methods [WT5”BZ]Mouse models of hyperoxia induced ischemic retinopathy were established. Retrobulbar injections were performed with VEGF antisense oligodeoxyribonucleotides or NS in 4 groups:normal control and various doses respectively. The nuclei of new vessel buds extending from the retina into the vitreous in different groups were counted and compared under the light microscope. Results There were plenty of new vessel buds in the eyes of mice in hyperoxic condition., while the number of the nuclei of new vessel buds is less in the murine eyes with retrobulbar injection of VEGF antisense oligodeoxyribonucleotides,especially the nuclei were redused with 59.3% in eyes with large dose. Conclusion The proliferation of retinal new vessel may be suppressed by using the retrobulbar injection of VEGF antisense oligodeoxyribonucleotides.

CD147 is a widely distributed cell surface glycoprotein that belongs to the Ig superfamily and is involved in various physiological and pathological activities.Highly expressed on the surface of many tumor cells,CD147 can promote tumor metastasis,angiogenesis and anchorage-independent growth.Targeting CD147 in cancer appears a promising therapeutic strategy.This review outlines the recent findings concerning the role of CD147 in tumor progression.

microRNAs ( miRNAs) are a family of short non-cod-ing RNAs that regulate the expression of target genes by binding to complementary regions. The miRNAs expression is readily al-tered by drugs, carcinogens, hormones, stress or diseases, and that might lead to changes in the drug metabolism, pharmacoki-netics or potency. Moreover, the evaluation of drug metabolic enzyme-related miRNAs would provide useful information for per-sonalized medicine. This review describes the current knowledge on the post-transcription regulation of drug metabolic enzymes by miRNAs.

Objective:To establish the quality standards for Zhichuan adhesive plasters;Methods:Herba ephedrae、Bergenin arolisiae、Flos caryophylli、Semen sinapis in Zhichuan adhesive plasters were identified by TLC. Ephedrine hydrachloride in Herba ephedrea was determined by RP HPLC.Results:These methods were simple and accurate.Conclusion: The methods can be used for the quality control of Zhichuan adhesive plasters.

A cross-sectional study was performed among 5134 health check-up subjects in Tianjin Municipality.Compared with control group [ (274 ± 76)μmol/L],patients with non-alcoholic fatty liver disease (NAFLD) had a higher level of serum uric acid[ (340 ± 81 )μmol/L]. Moreover,in NAFLD patients,along with the increase of the severity of fatty liver from mild,intermediate to severe,the serum levels of uric acid increased from (331 ±78),(347 ± 83) to (377 ±75 ) μmol/L ( F =19.68,P ＜0.01 ).Regression analysis found that sex(β=-0.43 ),serum triglyceride(β =0.53 ),fasting plasma glucose(β =-0.21 )and BMI(β =0.19) were associated with uric acid level in NAFLD patients; but insulin level and homeostasis model of assessment-insulin resistance were not associated with uric acid level. The results indicate that serum uric acid levels may be used as a biomarker for the severity of NAFLD.