The feasibility of medical college and university libraries to serve grass-root physicians was analyzed and the new approaches for medical college and university libraries to provide characteristic information service for grass-root physicians were studied according to the investigation of the utilization of information resources, types of information needs, satisfaction degree of information service, access methods of information, and hopes for access to medical information in grass-root physicians.

Objective To explore the diagnostic value of multi-slice spiral CT MIP-MPR image in regional lymph node metastasis of colonic carcinoma.Methods CT findings of 33 cases with pathological confirmed colonic carcinoma were analyzed retrospectively . All patients were underwent three-phase 256-slice CT dynamic enhancement scanning.All data were processed in workstation,to obtain routine MPR and MIP-MPR image.The regional lymph nodes of colon cancer were counted,and divided into 3 groups accord-ing to the short diameter of lymph node:group I (3.0-5.0 mm),group Ⅱ(5.1-10 mm),and group Ⅲ(10.1 mm up).The diag-nostic sensitivity of CT MPR and MIP-MPR image in checking out lymph nodes of different groups was compared by paired test.Re-sults The average value(x ±s )of lymph node number of three groups with routine MPR and MIP-MPR image were:group I, 3.66±1.99,6.09±2.44 (t=1 1.6,P <0.05);group Ⅱ,3.72±1.79,4.03±1.89 (t=3.73,P <0.05);group Ⅲ,1.21±1.31, 1.27±1.46(t=1.44,P >0.05).There were statistical differences in group I and group Ⅱ.Sensitivity of MIP-MPR image in chec-king out regional small and middle lymph nodes of colonic carcinoma was higher than routine MPR image.Conclusion Multi-slice spiral CT MIP-MPR image is a good way to checking out regional small and middle lymph nodes of colonic carcinoma.

Objective To investigate effects of octreotide combined with aspirin on the growth and metastasis of gastric cancer in vivo. Methods SGC-7901, human gastric cancer cell line, was implanted orthotopically in the stomach of nude mice. Octreotide or aspirin alone and the combination of the two drugs were administrated for 8 weeks to investigate the effects of them on tumor growth and metastasis. Results At necropsy, xenografts in situ were found in all stomachs of nude mice except two nude mice in the combined group. The mean volume and weight of tumors in nude mice treated with octreotide or aspirin were significantly lower than those of control group. The inhibitory rate for tumors was 60.6% in octreotide group, 39.3% in aspirin group and 85.6% in the combined group with octreotide and aspirin respectively. The metastatic rates of gastric adenocarcinoma were markedly lower in any of treatment group than that in control group. No severe side action was observed in all of treatment group. Conclusion Octreotide combined with aspirin greatly enhanced the anti-growth effect on gastric cancer in vivo when compared to using either of them and inhibited the metastasis of gastric adenocarcinoma in nude mice.

Objective To study MSCT findings and clinic value of hepatic abscesses on enhanced double-phase and(or)three-phase(arterial and protal venous phase and delayed phase),especially during arterial phase. Methods The MSCT imaging features of 20 cases with hepatic abscesses proved by operation or biopsy were evaluated on enhanced double-phase and(or) three-phase scan during arterial and portal venous phase and delayed phase ,especially during arterial phase.Results (1)The imaging features of aeterial phase were that the hepatic tissues around the lesions showed strong enhancement,but the lesions showed slight enhancement or not or peripheral enhancement. (2)The imaging features of protal venous phase were:a.circular target sign; b.circular sign; c.flower valve sign; d.multiloculated sign. (3)The imaging features of delayed phase were that the masses changed smaller or not and the belt disappeared or got vague. Conclusion The double-phase or three phase MSCT scan fully reflects the pathologic changes of hepatic abcesses and is very important to early diagnosis and differential diagnosis.

Objective To investigate the visual acuity improvement and related factors for myopia after femtosecond flap excimer laser surgery. Methods 72 myopic patients (129 eyes) in our hospital between January 2010 and December 2013 were chosen. The patients all received femtosecond flap excimer laser surgery. The visual acuity improvement after surgery was observed, and the influencing factors were analyzed. Results The distance vision (VA), near vision (NVA) and best corrected visual acuity (BCVA) significantly increased before surgery (P<0.05). Logistic regression analysis showed that preoperative BCVA, NVA, axial length, cutting ratio, axial length and time of near vision were the affecting factors of visual acuity (P<0.05). Conclusion Femtosecond flap excimer laser surgery for myopia has significant effect , but the preoperative visual acuity was affected by BCVA , NVA, cutting ratio, axial length and time of near vision.

Objective To present 8 cases of retroperitoneal laparoscopic pyelolithotomy or ureterolithotomy for the treatment of pelvis and ureteral stone. Methods 8 cases of pelvis or ureteral stone have been treated by retroperitoneal laparoscopic pyelolithotomy or ureterolithotomy. The size of the calculi was 0.8～2.4 cm with the incarceration time of 3 months～2 years.Details of the procedure were presented. Results Success has been achieved in all the patients and no complication has been observed during the 3～6 months of follow up. Conclusions Retroperitoneal laparoscopic pyelolithotomy or ureterolithotomy for the treatment of pelvis or ureteral stone is simple ,safe,less traumatic and effective.

OBJECTIVE To investigate the effect of the Qingfei decoction in the acute upper respiratory tract infections.METHODS From Jan 2004 to Sep 2006,there were 68 cases with acute upper respiratory tract infections treated with chinese medicines.The patients were divided into 2 groups:36 cases were treated with Qingfei decoction,32 cases were treated with Shuanghuanglian granules as a control.Both of the groups were treated for 5 days,the clinical symptoms such as: fever,cough and sore throat were used to evaluate the efficacy of both groups.RESULTS Both of the groups were effective;the effective rate was 88.9% and 75.0% in the Qingfei group and in the control group,respectively.There was significant difference between 2 groups(P

Objective To investigate the stabilization of betaine on the enzyme activity of ALT in human serum at different temperatures, and to evaluate the matrix effects of human serum with betaine among different analytical systems. Methods The enzyme activity of ALT in human serums with l mol/L betaine stored at 37 ℃, 25 ℃, 4 ℃ and - 20 ℃ respectively were measured. The matrix effect experiment was carried out according to the procedures specified in Clinical and Laboratory Standards Institute (CLSI)document EP14-A. Four analytical systems were the candidates for evaluation, and Roche Diagnostics (Roche)-Hitachi analytical system served as the reference system. The enzyme activity of ALT of 40 patient specimens and 3-level specimens ( high, medium and low) with 1 mol/L betaine were measured using the evaluated methods and the reference method respectively. The linear regression analysis was performed to compare the mean y value of 3-level specimens with the statistically defined limits ( the two-tailed 95% prediction interval) derived from 40 patient specimen data. Results The enzyme activity of ALT could be stabilized with betaine in serum, which remained to be 99% for 48 h at 37 ℃, 98% for4 d at 25 ℃, 97%for 4 weeks at 4 ℃, and 99% for 4 months at - 20 ℃. The enzyme activity of control serum decreased to 42%, 86%, 71%, 79% respectively. The mean y values of three specimens with the betaine were within the 95% prediction interval of the estimated mean y values, which suggested no obvious matrix effects in serum. Conclusion Betaine can be used in the development of enzyme ALT calibrator as its stabilizer.

Objective To analyze the clinical value of low molecular heparin calcium combined with early rehabilitation intervention in the prevention of deep vein thrombosis after internal fixation of intertrochanteric fractures.Methods 100 patients with internal fixation for treatment of femoral intertrochanteric fracture from January 2014 and October 2015 were selected and randomly divided into two groups:the control group of 50 cases, treated with low molecular weight heparin low molecular weight heparin by abdominal subcutaneous injection of drug therapy and routine nursing intervention service, observation group of 50 cases, in the control group based on the use of early rehabilitation intervention.The incidence of deep venous thrombosis after operation in two groups was recorded, and the changes of platelet count and coagulation markers were observed before and after intervention in the two groups.Results The observation group of patients with postoperative deep venous thrombosis incidence rate of 4%, significantly lower than the control group 16%, the difference was statistically significant (P<0.05), the two groups after the intervention each time the platelet count was higher than that of before intervention, four weeks after the intervention, the observation group of platelet count (239.51 ±34.62) ×109/L, significantly higher than the control group (235.23 ±28.87) ×109/L, the difference was statistically significant (P<0.05), the two groups before the intervention of each marker concentration, the difference was not statistically significant, patients in the observation group after the intervention, the blood coagulation markers concentrations were significantly lower than before treatment, and were significantly lower than the control group after the intervention.The comparison between the two groups, the difference was statistically significant (P<0.05).There was no chest pain, chest tightness, dyspnea and other symptoms of pulmonary embolism in the two groups , and no adverse reactions were found.Conclusion The application of low molecular weight heparin calcium combined with early rehabilitation intervention can effectively reduce the incidence of deep venous thrombosis after intertrochanteric fracture fixation.

OBJECTIVE:To analyze the current situation and developing trend of drugs used in hospitals of Chengdu.METHODS:The data of drugs purchased by 16 hospitals in Chengdu in the years 1997～2000 was collected and analysed.RESULTS:The drug expenses increased faster in years 1998～1999 and the drug expense in 2000 was 3 times as much as that in 1997.The proportion of sum of money spent on anti-infectives was decreasing year by year,which equaled that in developed cities of east China.CONCLUSION:The sum of money of drugs consumed will increase year by year,however,the growth rate may decrease.The proportion of consumption of imported drugs will continuously decrease.