OBJECTIVE:To study the stability of Ondansetron hydrochloride glucose injection(OHGI).METHODS:The contents of Ondansetron hydrochloride and its related substances were determined with HPLC.The stability of the samples were tested by high-light exposure,accelerating experiment and room temperature storage.RESULTS:After exposure to high light,the content in OHGI slightly decreased but on other experiments,it was rather stable.CONCLUSION:This injection should be kept away from high light and may be stored for2years at room temperature.

Objective:To study the mental health status of middle school students in Three-Gorges area of Chongqing in order to provide theory support for mental health education. Methods:1 014 middle school students in Three-Gorges area were tested by SCL-90. Results:The occurrent rate of mental problems with students was 19.8%,of which the first three factors were hostility,compulsiveness and interpersonal sensitivity. Girls’ overall score and mean scores of interpersonal sensitivity, depression,anxiety and phobic anxiety were significantly higher than boys’. The overall score and factor mean scores of senior high school students were significantly higher than those of junior high school students’ except hostility and phobic anxiety factors. The mean scores of interpersonal sensitivity,hostility and phobic anxiety factors were significantly higher than the counterparts in the norms of middle school students,while the mean scores of somatization and anxiety factors were significantly lower than the counterpart in the norms of middle school students. Conclusion:The mental health status of middle school students in Three-Gorges area of Chongqing is poor,and mental health education should be enhanced by all of us.

Objective:To investigate the effect of liver ultrasonography and the security to rabbits with hydrogen peroxide(H 2O 2) affused by rectum.Methods:48 rabbits were divided into 4 groups according to different H 2O 2 concentrations,and each group was divided into 4 groups according to different H 2O 2 dosages. Each rabbit was affused with H 2O 2 by rectum,then the effect of liver ultrasonography was observed,and the damages to the tissues of rabbits were pathologically checked.Results:The liver structure could be clearly developed with 1% H 2O 2 10ml affused,and the liver gray value increased with the H 2O 2 concentration increased.The time from affusion to develop was shortened and the duration of high echo was prolonged.But at same H 2O 2 concentration,the time to develop was not significantly different with the H 2O 2 dosage increased,and the high echo was decreased more slowly.The average survival time of rabbits was significantly negatively correlated to the H 2O 2 concentration(?=-0.99),while the damage degree was significantly positively correlated (?=+0.99).Conclusion:H 2O 2 affusion can induce damage to tissues and microcirculation,while produce better liver ultrasound image,so it is important to chose suitable H 2O 2 concentration and dosage,to extend its clinical application.

After a description of the concept and characteristics of metaliteracy, the main institutions shouldering the task of metaliteracy education were summarized, including government and fund organizations, faculties, scien-tific research office, and teaching group. Of these institutions, library plays a major role in metaliteracy education since it is not only the main driving force of metaliteracy education and the institution to make,file and maintain the resources for metaliteracy education, but also is the organizer, coordinator and manager of metaliteracy teachers.

In recent years,with the criterion and scaling up of newborn screening work,not only the rates of neonatal congenital hypothyroidism screening increased year by year but also more and more neonatal hyperthyrotropinemia children have been found.How to correctly understand the neonatal hyperthyrotropinemia is still one of the problems in the clinical work.This article will review the causes,diagnosis,prognosis and treatment principles of hyperthyrotropinemia.

OBJECTIVE:To improve the formula of urea cream and establish its quality control methods.METHODS:The matrix component of formula was adjusted to prepare O/W matrix.Prednisone was added into matrix to prepare urea cream;UV spectrophotometry was applied to determine the content of urea and evaluate the quality of preparation and the stability of 3 batches of samples setting for 40 days under different conditions.RESULTS:The preparation was white cream and its inspection results were in line with the standards stated in Chinese Pharmacopoeia(2005 edition).The linear range of urea was 30.5～180.2 ?g?mL-1(r=0.999 0) with an average recovery of 99.68%(RSD=0.49%).The quality of 3 batches of samples kept stable during observation.CONCLUSION:Improved formula is reasonable,simple in preparation technology and quality control.

There were 417 scientific articles on hematopoietic stem cell transplantation in the 54th annual meeting of American Society of Hematology (ASH),including 46 articles on lymphoma.This article reviews latest research on non-myeloablative allogeneic hematopoietic stem cell transplantation for the treatment non-Hodgkin' s lymphoma presented in the meeting.

Objective To evaluate the curative effects of venlafaxine in patients with depressive disorder between therapeutic modes of inpatient and outpatient. Methods Seventy-two patients with depressive disorder including 36 inpatients and 36 outpatients were measured respectively with HAMD24 after treatment for 1 week, 2 weeks, 4 weeks and 8 weeks, and then the curative effects were compared between two groups. Results It was found that all patients in the inpatient group completed the observation and two patients in the outpatient group didn’t complete the observation. The HAMD24 score was significantly decreased in the inpatient group than that of the outpatient group from the second week to the end of the eighth week (P<0.05). The total effective rates were 80.6% for inpatient group and 64.7% for outpatient group, no significant difference between them. Conclusion Venlafaxine shows a higher therapeutic value and outcome in the therapeutic mode of inpatient.

Objective To search the status quo of students'thanatopsis in order to push focused education on terminal care to the nursing major students.Metheds To distribute home-made questionnaire to 268 nursing students.Results students who cannot talk about death normally account for 21.3 percent;who never considered death or unnecessary to consider death account for 12.9 percent of the total;who considered a lot account for 10 percent;who cannot handle terminally ill account for 74.3 percent;and who prefer self-suicide when suffered defeat account for 4.9 percent.Conclusion Nursing students have insufficient ideas of death,and they need to think deeply about the meaning of death and to nurture a positive outlook on death in order to get a correct terminal care education.