Green tea extract decreased lipid metabolism disorders on rabbit consuming cholesterol in experiment through the improvement of plasma TG, TC, LDL-C level. This effect depends on the doses of cholesterol and the drinking periods. The dose of 150mg/kg/day gave best effect.
Lipids ; Cholesterol ;

A controlled prospective study included 50 normal Swiss white mice and 62 patients with mild and moderate hypertension without blood lipid metabolic disorder were divided into two groups randomly. The control group: 31 patients treated by Caporil 25mg, two tablets twice daily, (at 12 hours intervals). The study group: 31 take a TT1 prescription daily within 28 days continuously. The result showed that: No acute toxicity from TT1 prescription on trial dose of white mice: 50g/kg. No side effects occur when the patient uses a TT1 prescription daily. No blood lipid metabolic disorder on mild and moderate hypertension patients. TT1 had clearly good efficacy on hypotension. This efficacy after two weeks treatment is less effective than Caporil 25mg, twice daily but equivalent with Caporil 25mg, twice daily after 4 weeks. Some symptoms such as dazzle, dizziness, headache, red face, red eyes, tightness on chest had improved by TT1 and it was much better than Caporil.
Hypertension ; Lipids ; Blood ; Therapeutics

59 patients diagnosed to be hypertention and the control group with 39 subjects without hypertention treated in Thai Nguyen Hospital from 10/4/2002 - 10/4/2003. The results follows: 66.1% of patients with primary hypertention have disorders of lipid index as compared to a control group. 39.0% of these patients have an increase in total cholesterol and these levels in a case group higher than those in a control group. 27.15% of these patients have an increase in serum triglycerid levels and these levels in a case group higher than those in a control group. 61.0% of these patients have a decrease in serum HDL-C levels and these levels in a case group higher than those in a control group. CT/HDL-C ratio in a case group is 5.25 and in a control is 3.70. They are in upper limit of normal value.
Hypertension ; Lipids ; Serum

A prospective and cross-sectional study was conducted on 70 chronic renal inflammation patients with nephritic syndrome without using lipid lowering drugs for 1 month before the study. Nephritic syndrome was characterized by severity edema, urinary protein ≥ 3.5g/24 hours, protein < 60g/l, albumin < 30g/l, elevated levels of cholesterol, triglyceride. Results of the study: among these patients, 100% with elevated cholesterol, ApoA1 and ApoB, 97.14% with elevated triglyceride, 62.86% with elevated LDL-C, 68.57% with elevated ApoA1, 48.57% with low HDL-C. Cholesterol level had a significant reverse correlation with serum protein; cholesterol, triglyceride, and LDL-C levels had significant reverse correlations with serum albumin
Nephritis, Lipids, Serum, Proteins

Investigation on 72 diabetics in Ha Noi communities found that: Lipaemia disorders of diabetics were high. Among cholesterol total (CT) increased acquired 41.67%, trigleceride (TG) increased acquired 38.89%, high density lipid (HDLC) decreased acquired 26.39% and low density lipid (LDLC) increased acquired 25%. The disorders associated 2 lipid index commonly was: CT increased associated with LDLC increased, then CT increased associated with TG increased and CT increased associated with high density lipid HDLC decreased. The complications indiabetics with lipeamia disorders such as: hypertension, visual acuity decreased, retinopathy and peripheral neural lesions
Diabetes Mellitus ; lipids ; blood

A study was carried out on 51 patients with hypertension and blood lipid metabolism disorder at the Clinic Department and Heart-Renal-Joint Department in the Military Traditional Hospital and at the General Enterology Department in the Son Tay Hospital from Feb 2004 to Sept 2004. The patients were divided into two groups: study group included 2 patients using a TT2 traditional repice/day for 28 days; control group included 9 patients using Caporil 25mg x 2 tablets/day for 28 days. 50 white mousses of Swiss species were provided by The National Institute of Hygiene and Epidemiology. TT2 experiment showed no acute toxicity with experimental dose 50g/1kg of mouse weight. Boiling and drinking a TT2 traditional repice/day did not cause any side effects. TT2 helps to decrease blood pressure significantly in patients with hypertension and blood lipid metabolism disorder. After 4 weeks, the blood pressure level in patients using TT2 is as equivalent as in patients using Caporil 25mg x 2 tablets/day. TT2 improves symptoms of the both of disease type: dizzy, headache, neck pain, dyspepsia, insomnia, lose appetite, red face, red eyes and constipation.
Hypertension ; Lipids ; Therapeutics

Study on the peroxidation of membrane lipid and the change of some anti-oxidant enzymes during the storage of erythrocytes by additive system. The invitro study was conducted with two additive systems: one is the AS-T which is the first preparation in VN and the other is the preparation of Terumo, a leading company of the world on the blood preparations. The results demonstrate that the two systems are equally in the anti-peroxidation activation of membrance lipid. The ability to maintain enzyme activation of Superoxyd dismutase (SOD) and Gluathion peroxidase (GCH-Px) of erythrocytes during of storage process (from ) to 35 days), the erythrocyte mass which is preserved by AST solution abilize activity of SOD and GSH-Px better than by Terumo solution, with this result os signficant slower increasing of MDA concentration at the end of storage
Lipids ; Intracellular Membranes ; Erythrocytes

Liposomes with precisely controlled composition are usually used as membrane model systems to investigate the fundamental interactions of membrane components under well-defined conditions. Hydration method is the most common method for liposome formation which is found to be influenced by composition of the medium. In this paper, the effects of small alcohol (ethanol) on the hydration of lipid molecules and the formation of liposomes were investigated, as well as its coexistence with sodium chloride. It was found that ethanol showed the opposite effect to that of sodium chloride on the hydration of lipid molecules and the formation of liposomes. The presence of ethanol promoted the formation of liposomes within a certain range of ethanol content, but that of sodium chloride suppressed the liposome formation. By investigating the fluorescence intensity and continuity of the swelled membranes as a function of contents of ethanol and sodium chloride, it was found that sodium chloride and ethanol showed the additive effect on the hydration of lipid molecules when they coexisted in the medium. The results may provide some reference for the efficient preparation of liposomes.
Ethanol/pharmacology* ; Lipids ; Liposomes

This study was carried out on 91 participants. They were divided into 2 groups: 60 patients with type 2 diabetic mellitus, aged more than 40 years were involved in one group and 31 non-diabetics matched by age were served as control group. Symptoms and complications of diabetes were determined by physical examination. Waist and hip circumferences were measured and BMI and waist to hip ratio was calculated. Fasting blood samples were collected and analyzed for glucose, total cholesterol, triglycerid, HDL-C, Apo A1 and Apo A2. The total cholesterol to HDL-C and Apo A1 to Apo A2 ratios were calculated from the result of lipid parameters. The findings of research suggested that the lipoprotein profile in type 2 diabetics was characterized by elevation of serum triglyceride, lowering in HDL-C and increasing in total cholesterol to HDL-C ratio. Most of patients a moderate BMI (53.44%) but the central obesity was common (63.71%). The waist circumference was positively correlated with triglyceride concentration (r = 0.3). The waist to hip ratio was negatively correlated with HDL-C concentration (r = -0.45) and positively correlated with total cholesterol to HDL-C ratio (r = 0.3).
Diabetes Mellitus, Type 2 ; Lipids

The study of 165 the elderly with hypertension and 50 healthy people of the controls at An Hai District - Hai Phong. The hypertension: the age group of 60 - 70 is 60.61%. Blood lipid disorder of the elderly with hypertension is 61.68%; the mean cholesterol total increasing in the age group, the average triglycerid is most increased at the age group of 75 - 84 (2,02 mmol/l); the average HDL-C is the lowest at the age group of 75 - 84 (1.05 mmol/l); LDL-C increasing follow age. Blood glucose, blood creatinin of the elderly with hypertension is much higher than in the controls people
Lipids ; Blood ; Aged ; Hypertension ; Epidemiology