Objective To compare the objective cure rate and perioperative complications 0f ten-sion free vaginal tape(TVT)and laparoscopic Burch for the treatment of fernale stress urinarv inconti-nence. Methods Literature search was conducted for all randomized control trials(RCTs)between 1994 and 2006,using MEDLINE,EMBASE with the keyword"tension free vaginal tape","colpo-suspension","stress urinary incontinence",then a second search was performed with the following keywords:[(tension free vaginal tape),AND(colposuspension),OR(Burch)],AND stress urinary incontinence].Gray literature was search in The Cochrane central register of controlled trials、NRR (National Research Register)、CCT(clinical controlled trials),ISTP,ISI proceedings,OCLC First-search proceedings,(CACP),GreyNet(http://www.greynet.org/)、DARE(Database of Abstract:s of Reviews of Effects)、SIGLE(System for Information on Grey Literature in Europc),official website of ICS.Meta-analysis was performed with RevMan software 4.2. Results right studies were included comparing objective cure rate and perioperative complications of TVT and LB.Overall objective cure rates were 233/259 for TVT and 189/247 for Burch respectively.TVT shared higher objective cure (RR 1.19,95%CI 1.10-1.29,P<0.01)and lower perioperative complications(RR 0.48,95%CI 0.32-0.71,P<0.05). Conclusions The available evidence indicates that TVT is an effective treat-ment for stress urinary incontinence with higher objective cure rate and 10wer perioperative complica-tions compared with LB.

OBJECTIVETo understand the clinical feature and natural course of polycythemia vera (PV).

METHODSThe clinical symptoms, signs, laboratory examination and prognosis of 185 patients with PV were analysed.

RESULTSThere are 122 males and 63 females. The mean age was (52.7 +/- 14.1) years. The mean hemoglobin level was (208.3 +/- 21.2) g/L. Pancytosis was displayed in 74 (40%) cases, excess of red blood cells in 33 (17.8%), excess of red blood cells and granulocytes in 67 (36.2%) and excess of red blood cell and platelets in 11 (5.9%). Splenomegaly was found in 123 (66.5%) patients and hepatomegaly in 30 (16.2%). Quantitative assess of serum Epo was done in 25 patients. The level was low in 16 (64.2%) and normal in 9 (36.0%). Hematopoietic progenitor culture yields was elevated in 11 patients, endogenous erythroid colonies (EEC) formation was found in 10 cases (90.9%). Eighty two patients (44.3%) had 101 attacks of vascular thrombotic incidents, 7 patients developed myelofibrosis (MF). Secondary cancer occurred in 1 patient. Two patients died of thrombosis.

CONCLUSIONPV is an elderly adult myeloproliferative disease with a high frequency of thrombosis. EEC can be found out in PV patients. The serum Epo level is not increased in PV patients. The main sequelae of PV is MF.

Adult ; Aged ; Erythrocyte Count ; Female ; Hemoglobins ; metabolism ; Hepatomegaly ; etiology ; Humans ; Leukocyte Count ; Male ; Middle Aged ; Polycythemia Vera ; blood ; complications ; pathology ; Primary Myelofibrosis ; etiology ; Splenomegaly ; etiology ; Thrombosis ; etiology