Objective To discuss the diagnostic value of regular ultrasonic combined with ultrasonography micro-vessel enhanced presentation for breast malignant disease.Methods 152 patients with single breast tumour were collected,they were examined by regular ultrasonic,ultrasonography micro-vessel enhanced presentation before operation and received regular pathology after operation.The diagnostic sensitivity,specificity,negative predictor,positive predictor,accuracy,area under ROC curve,95 ％ reliable interval of regular ultrasonic,ultrasonography micro-vessel enhanced presentation and the combination for breast malignant disease were analyzed.Results Ultrasonography micro-vessel enhanced presentation is better than regular ultrasonic in the diagnostic sensitivity,specificity,negative predictor,positive predictor,accuracy (P =0.002).The combination of regular ultrasonic and ultrasonography microvessel enhanced presentation could improve the detection rate of breast malignant disease(regular ultrasonic compared with combination,P =0.002 ; ultrasonography micro-vessel enhanced presentation compared with combination,P =0.000) and increase area under ROC curve (P =0.000).Conclusion Regular ultrasonic combined with ultrasonography micro-vessel enhanced presentation has complementary advantages and can increase early detection rate for breast malignant disease.

Objective To explore the correlation between the TCM syndromes of mammary hyperplasia patients and their sex hormones,molybdenum target radiography image to establish the objective indexes for its syndrome differentiation.Methods According to the TCM syndrome differentiation,the 346 patients with mammary hyperplasia were diagnosed liver qi stagnation syndrome,phlegm and blood-stasis syndrome,and chong and ren dysfunction syndrome.Their pituitary gonad stimulating hormones,including estradiol(E2),progesterone(PP),testosterone(PT),prolactin releasing hormone(PRL),follicle-stimulating hormone(FSH),and luteotropic hormone(LH) were measured during ovulatory period.At the same time,the molybdenum target radiography examination was given.Results The level of FSH,LH and E2 in mammary hyperplasia patients during ovulatory period was obviously lower,the level of PRL and PP was obviously higher,and the level of PT was not obviously changed.The comparison among groups showed that the level of FSH in chong and ren dysfunction patients was higher than that in liver qi stagnation patients,but the level of LH of the two was just opposite;the level of E2 was lower in an order of liver qi stagnation,phlegm and blood-stasis,and chong and ren dysfunction patients;the molybdenum target radiography image showed that there was mainly the lobular hyperplasia in liver qi stagnation and phlegm and blood-stasis patients and then the nodular type;but there was mainly nodular hyperplasia in chong and ren dysfunction patients and then the lobular type.Conclusion The pituitary gonad stimulating hormones of mammary hyperplasia patients were disordered in the duration of ovulatory period.The level of sex hormones and change of molybdenum target radiography image were different in different TCM syndromes and they can be used as one of the objective indices in TCM syndrome differentiation for diagnosis.