1.The application of serum albumin and plasma von Willebrand factor in patients with stroke
Lingqin ZHOU ; Chaorong ZHAO ; Qingwen DONG ; Xiangyong HUANG ; Liqin SUN
Chinese Journal of Primary Medicine and Pharmacy 2006;0(06):-
Objective To evaluate the monitoring value of serum albumin and plasma von willebrand factor in patients with stroke.Methods Serum albumin and plasma von willebrand factor were measured from 145 patients with stroke(95 patients with nonpoor outcome and 50 patients with poor outcome) in two weeks and after six months from stroke onset to study the relationships with prognosis.Results Serum albumin level was significantly higher in patients with nonpoor outcome(mRS≤2) after six months stroke onset than those with poor outcome(mRS≥3) and was lower after six months stroke onset than in two weeks from stroke onset.On the other hand,plasma vWF level in patients with stroke was significantly higher than that in healthy controls and was higher in two weeks than after six months from stroke onset.Patients with poor outcome had higher plasma vWF level than patients with nonpoor outcome in two weeks and after six months from stroke onset,but had no significant difference.Conclusion The level of serum albumin and plasma von willebrand factor is related with nutritional status,active extent and prognosis in patients with stroke.
2.Association between metabolic syndrome and prognosis of endometrioid carcinoma
Juan NI ; Hanmei LOU ; Tao ZHU ; Lingqin ZHAO ; Huafeng SHOU
Chinese Journal of Obstetrics and Gynecology 2014;49(10):768-771
Objective To study the association between metabolic syndrome (MS) and prognosis of endometrioid carcinoma.Methods A total of 256 patients with endometrioid carcinoma at,Zhejiang Cancer Hospital between January,2001 and December,2008 were chosen.The deadline for follow up was December 2008.The general conditions(including age and body mass index),whether coupled with MS and it's risk factors(including waist circumference,fasting plasma glucose,triglycerides,high-densitylipoprotein,systolic and diastolic blood pressure) were analyzed.The outcome of 256 patients whether coupled with MS were analyzed using Kaplan-Meier curve.Relative risks were estimated using Cox proportional hazards regression model.Results A total of 256 cases were followed-up successfully.Sixtyfour (33.0%) cases coupled with MS among the 194 patients survived,while thirty-two (51.6%)coupled with MS from 62 cases died,there was significant difference between them (x2=6.953,P=0.008).The total fiveyear survival rate was 75.8%,the survival time was (78.0±3.4) months.The rate and the survival time of patients coupled with MS [66.7%,(67.0±2.4) months] were significatly lower than those coupled with no MS [81.3%,(85.0±4.0) months;P<0.05].The Cox proportional hazards regression results showed that coupled with MS,body mass index ≥25 kg/m2,waist circumference>80 cm,abnormol systolic and diastolic blood pressure,abnormal fasting plasma glucose and more than two components of definitions of MS were related to bad prognosis of endometrioid carcinoma(P<0.05).Conclusion Metabolic syndrome may be lead to a bad prognosis of endometrioid carcinoma.