1.Design and realization of the oncology follow up system base on oncology information system
China Medical Equipment 2013;(11):37-38,39
Objective: To research on the design and development of the Oncology Follow up System base on Oncology Information System. Methods: To analyze the workflow of follow up. Design the architecture of the system software. Discuss the development of the important modules such as the interface, the follow up reminder, the follow up recorder and the follow up searcher. Results:To develop the follow up system of the radiotherapy department, including the interface for oncology information system, the follow-up remind module, the follow-up input and the follow-up query module. Conclusion:Through building the follow up system of the radiology department, can provide great help to doctor’s clinical work, improve the doctor’s working and researching efficiency, and improve the patients’ satisfaction.
2.The investigation and analysis of medical postgraduates' ! honesty education
Chinese Journal of Medical Education Research 2016;15(11):1110-1114
Objective To understand the current situation of medical postgraduates'!honesty edu-cation, find the weak point and explore new ways of the honesty education. Methods The honesty educa-tion survey questionnaire was designed and conducted to the postgraduates of Grade 2014 in Peking University Health Science Center. The research contents included the basic information of postgraduates, honesty cognition, clean and self-discipline, honesty education, the recommendation of honesty education and the application of honesty education carrier. 1 038 questionnaires of a total of 1 142 questionnaires were recovered and the recovery rate was 90.9%. EPIData3.0 software was used for double entry and database establishment, and SPSS 19.0 software for statistical treatment. Results 82.3% (854) of the postgraduates recognized the work of clean government, but only 62.1% (644) of the postgraduates concerned about it. 78.3% (813) of the postgraduates expressed hatred for the dishonest behavior and hoped to eliminate it. 77.6%(806) postgraduates often paid attention to honest education content which was pushed by the new media. 16.5% (171) postgraduates thought that the new media was very important to the honest cognition. Conclusions We should pay more attention to medical postgraduates'!honesty education, find its weak points according to the investigation and make full use of the network and new media. And at the same time we should combine the actual environment to establish a hierarchy of honesty education system, and carry out honesty education through total environment which contains the school administrators, instructors/head teachers and tutors.
3.Clinical Efficacy of CAG Regimen Used in 35 Cases of Newly Diagnosed Acute Myeloid Leukemia in Elder-ly Patients
China Pharmacist 2015;(8):1366-1367,1368
To study the efficacy of CAG regimen used in 35 cases of newly diagnosed acute myeloid leukemia in elder-ly patients. Methods:Totally 35 cases of elderly patients with acute myeloid leukemia were randomly divided into two groups. The pa-tients in the control group (15 cases) were treated with standard chemotherapy treatment, while the CAG regimen group (20 cases) was treated with CAG regimen (cytarabine, aclarubicin and granulocyte colony-stimulating factor). After one treatment course, the chemotherapy efficacy was observed, and the neutrophil and platelet recovery time and the incidence of adverse reactions in the two groups were compared. Results:The treatment efficacy of the CAG regimen group was 90%, which was higher than that of the control group (60%, P<0. 05). The neutrophil and platelet recovery time of the CAG regimen group was significantly shorter than that of the control group (P<0. 05). The incidence of adverse reactions in CAG regimen group was much lower than that of the control group(P<0. 05). Conclusion:The efficacy of CAG regimen used in the 35 cases of newly diagnosed acute myeloid leukemia in elderly pa-tients is promising, which can effectively control the progression of the disease and accelerate blood cell recovery with high safety.
4.The building and application of Bank-hospital connection system
Lingling GUO ; Fukang JIANG ; Fei HAO
China Medical Equipment 2015;(3):51-53
Objective:Through the construction of the Bank-Hospital connecting project, the enduring problems in clinic such as the long waiting time at registration, check out, payment, and other non-clinic issues are solved. Meanwhile, the clinic medication procedure is further regulated, which provides a faster medical assistance service for patients and elevates the ability to apply medical informationization.Methods:Based on the current HIS platform, the banking and mobile systems connected as a whole network and constructed the banking-medication platform. Results: The waiting time of patients is largely reduced by expanding the channels of registration, applying multiple cards as medication card, and introducing local charging, self-payment systems at every floor, and mobile intelligent platform.Conclusion: The Bank-Hospital connecting project brings convenience to patients and increases our efficiency.
5.The protective effect of dopamine on the noiseinduced hearing loss of guinea pigs
Lingling GUO ; Lisheng YU ; Xingqi LI
Chinese Archives of Otolaryngology-Head and Neck Surgery 2006;0(08):-
OBJECTIVE To investigate the protective effect and its frequency selection of dopamine on the inner cell in cochlea when exposed to white-noise;In order to offer an important step on understanding of negative protective modulation of dopamine in the cochlear auditory afferent nerve. METHODS Forty guinea pigs were randomly divided into 4 groups and whole intracochlear perfusions were performed. ① exposed to the 100dB white-noise; ② perfused with artificial perilymph solutions; ③exposed to the white-noise and perfused with artificial perilymph solutions; ④exposed to the white-noise and perfused with Artificial perilymph solutions containing 1mmol/L dopamine. Compound action potential(CAP)evoked by different frequencies tone pip, and cochlear mirophonics(CM)evoked by 4kHz tone burst were recorded from the round window of guinea pigs before and 2h after perfusion. RESULTS In the groups exposed to the white-noise, the CM amplitude and the linearity of input-output function both significantly decreased at 2h(P
7.Research advances in relationship between methyl-CpG binding domain proteins and the repression of tumor repressor genes
Lingling GUO ; Fengying DUAN ; Xiaohua QIU
Cancer Research and Clinic 2008;20(3):211-213
Many genetic events have been described to be involved in the development of tumor,but a lot of recent researches proved that epigenic events also played an important role in it.DNA methylation is one of the common modification of epigenic events,the binding of methyl-CpG binding domain proteins has been shown to lead to transcriptional repression of many tumor repressor genes.
8.Application of mentor-mentee two-way evaluation in the academic ethics trainings for post graduate students
Lingling GUO ; Liping DUAN ; Jinzhong JIA
Chinese Journal of Medical Science Research Management 2017;30(1):31-34,55
Academic ethics is closely related to the construction of the world class disciplines,the academic ethics of university mentors and their graduate students are especially important to the development of disciplines and Universities.This article was based on a survey which used two-way evaluation conducted at Peking University Health Science Center,investigated the cognition,current status,misconduct and possible causes,as well as related trainings of academic ethics between mentors and mentees,furthermore,this article also analyzed the application of mentor-mentee two-way evaluation in the academic ethics trainings for post graduate students.
9.Study of comparison of optic nerve between big cupped disc and early glaucoma
Juan GUO ; Lingling WU ; Gege XIAO
Ophthalmology in China 1994;0(02):-
Objective To investigate the sensitivity of Heidelberg Retina Tomography (HRT-Ⅱ)parameters on the early optic nerve change of glaucoma head. Design Cross-sectional study. Participants Twenty-one patients (36 eyes) with big cupped disc(C/ D≥0.7) and twenty-seven patients (31 eyes) with early glaucoma (C/D≥0.7, MD≤3dB) were studied. Methods All patients underwent visual field and HRT-Ⅱ examination to get parameters of optic nerve head. T test was used to compare the parameters of optic disc between big cupped disc and early glaucoma. Main Outcome Measures HRT Ⅱ parameters included disc area, cup area, rim area, cup volume, rim volume, C/D area ratio, mean cup depth, maximum cup depth, cup shape measure, height variation contour, mean RNFL thickness and RNFL cross sectional area. Results Statistics analysis with T test (t=2.247-3.714, P=0.000-0.028) showed there were significant differences of rim area, rim volume, mean retinal nerve fiber layer thickness, sectional area of retinal nerve fiber layer between big cupped disc and early glaucoma. Conclusions We can pay attention to those parameters with HRT- Ⅱ to distinguish patients with big cupped disc and early glaucoma.
10.Effects of early hyperbaric oxygen therapy on function recovery in spinal cord injury patients
Genping GUO ; Qian ZHANG ; Lingling YANG
Chinese Journal of Rehabilitation Theory and Practice 2005;11(9):758-758
ObjectiveTo investigate the effect of early hyperbaric oxygen therapy on function recovery in spinal cord injury(SCI)patients.Methods216 SCI patients were randomly divided into early hyperbaric oxygen therapy group(E, 108 cases)and late hyperbaric oxygen therapy group(L, 108 cases).The patients in both groups received the similar rehabilitation and medicine treatment. The effects were assessd by the American Spine Injury Association(ASIA)and modified Barthel index(MBI).ResultsThere was no difference between two groups before treatment, and the scores improved significantly after treatment, but the scores of the group E was significantly higher than that of the group L. ConclusionHyperbaric oxygen therapy can facilitate the function recovery, and it is better to interfere early.