1.Effects of Processing on Antioxidation of Ramulus Cinnamomi
Chen YANG ; Xi QUI ; Lingdong KONG ;
Chinese Traditional Patent Medicine 1992;0(03):-
Objective: To investigate the effects of processing on antioxidation of Ramulus Cinnamomi .Method: The oxygen free radicals generation system in vitro and mouse liver homogenate lipid peroxidation reaction induced by hydroxy free radicals were used to estimate the effects. Results: Aqueous extracts of different processed products of Ramulus Cinnamomi were stronger than the alcohol extracts in the scavenging superoxide anion (O 2 -), but weaker in the scavenging hydroxyl free radical (?OH) and the anti lipid peroxidation. There were some existed differences among the different processed products. Conclusion: The processing affected the anti oxidation of Ramulus Cinnamomi .
2.Hospital operational data center:building and application
Gang YU ; Lingdong CHEN ; Hongbo ZHANG ; Zhujing CHEN
Chinese Journal of Hospital Administration 2017;33(3):206-208
This paper discussed the method and procedure of building a hospital operational data center,and introduced the application of its service with examples.Three aspects discussed in the paper cover the setup of information standard,integration of heterogeneous data resources,and flexible data presentation.Other issues discussed include key challenges and solutions for development of hospital data center systems.Such a platform enables the hospital in a successful standardization and structural management of its clinical data.
3.An evaluation of Mandard tumor regression grade system in patients with locally advanced rectal cancer treated with preoperative radiotherapy
Lingdong SHAO ; Jinluan LI ; Kaixin DU ; Junyan HE ; Shaohua CHEN ; Xuehong LIAO ; Qingqin PENG ; Junxin WU
Chinese Journal of Radiological Medicine and Protection 2017;37(8):587-593
Objective To explore the clinical and imaging factors influencing the patients' prognosis after preoperative radiotherapy for local advanced rectal cancer.Methods We retrospectively analyzed 106 locally advanced rectal cancer patients from June 2004 to September 2015 in our institution.All patients underwent preoperative radiotherapy.According to the Mandard score,patients were divided into 5 groups (TRG1-5).All patients were divided into two groups according to the TRG,which including good responder (TRG1 + 2) and poor responder (TRG3 + 4 + 5) groups.All of the tumor ADC values of post-RT were measured by Diffusion-weighted MRI technology,and the relationship between tumor ADC values of post-RT and TRG was analyzed.Results In univariate analysis,age,chemotherapy,pT,pN,differentiation degree,vascular invasion and TRG were significantly associated with overall survival (x2 =3.945-8.110,P < 0.05).Multivariate analysis indicated that differentiation degree and TRG were the independent prognostic factors for OS (x2 =5.221,6.563,P < 0.05).No significant difference was found between long-course and short-course radiotherapy group (P > 0.05) in OS.The good responder group had a favorable survival in 5-year OS compared to the poor responder group (x2 =8.110,P < 0.05).Preoperative radiotherapy,preoperative chemotherapy,pathological type,differentiation degree and gross type,vascular tumor thrombus and tumor ADC values of post-RT were significantly associated with TRG (x2 =4.189-18.139,P < 0.05).The best critical point of tumor ADC values of post-RT was 1.7 x 10-3 mm2/s by using ROC curve.The accuracy of tumor ADC values of post-RT in predicting TRG1 + 2 was 70%.Conclusions The TRG can predict the efficacy of preoperative radiotherapy in patients with locally advanced rectal cancer based on the Mandard score.There was no significant difference in OS between long-course radiotherapy group and short-course radiotherapy group.The tumor ADC values of post-RT might become a potential factor to predict TRG in patients with locally advanced rectal cancer after preoperative radiotherapy.
4.Outpatient clinic process enhancement at children's hospital: empowered by information technology
Gang YU ; Yonggen ZHAO ; Lingdong CHEN ; Zheming LI ; Cenliang WU ; Tianlin WANG
Chinese Journal of Hospital Administration 2018;34(9):753-755
On the basis of the existing appointment process, artificial intelligence and Internet of things technologies were introduced to optimize such process. Thanks to the all appointment process management empowered by AI and IoT, patient waiting time is cut short and patient satisfaction enhanced as a result.