To evaluate the forensic determination of post cerebral traumatic epilepsy. Methods In 21 patients, traumatic history and previous history were analysied combined with the demonstrations of electroencephalogram(EEG), X-ray, CT and MRI. Results Post-traumatic epilepsy,manily in late stage, usually occurred following serious cerebral trauma. The type of traumatic epilepsy was determined by the traumatic location and extent. Abnormal epileptic wave in scalp EEG and 24h dynamic EEG and medical image examinations were helpful for qualitative analysis. Conclusion The forensic determination of post traumatic epilepsy must be on the basis of traumatic and previous history combined with EEG, CT and MRI analysis.

The serous anti-corneum antibodies(ACAs)of 50 psoriatic patients and 32 normal con- trols were measured by Biotin Avidim Enzyme Linked Immunosorbent Assay (BA-ELISA).The results showed that ACAs of patients were significantly lower than that of the controls(P

Objective To investigate and improve the methods of nasal feeding to reduce the occurrence of complication such as diarrhea and vomiting.Methods We separated 140 patients with heavy craniocerebral injury into the control group (50 patients) and the experimental group (90 patients) according to different nasal feeding methods. For the control group traditional method was used. For the experimental group infusion pump was used to control infusion rate. The incidence of complication was compared between two groups. And within experimental group, the same nutrient solutions in respect of type and volume were infused during 10 hours, 16 hours, and 18 hours respectively. The relationship between infusion rate and the occurrence of complication was observed, analyzed and compared to seek for the most suitable enteral nutrition route which incurred the least complication.Results The incidence of diarrhea and vomiting in the experimental group was lower than that of the control group. And there were no significant differences in the occurrence of complication by using infusion pump at three different infusion rates within the experimental group. Conclusions The application of infusion pump in nasal feeding can reduce the incidence of complication and infusing nutrient solution at a slow rate was not necessary.

Objective To select health individual and test serum total bilirubin and direct bilimbin in order to provide a reference range for the establishment of appropriate reference interval in this region.Methods From October to December in 2009,314 of physical examination population of Beijing Hospital were selected by questionnaire and laboratory test excluding liver and gallbladder diseases or metabolic diseases.Roche and Prodia reagents were used to test TBIL and DBIL,respectively.Reference interval was calculated by sex group and compared with the existing reference interval.Results The level of TBIL had a significant difference between different genders(P ＜ 0.01).The level of TBIL had a significant difference between two kinds of reagents(P ＜ 0.01).Using Roche reagent,the reference interval of TBIL was 7.1 ～ 27.2 μmol/L for man,and 4.8 ～ 20.9 μmol/L for woman,and the reference interval of DBIL was 1.4 ～6.8 μmol/L for man,and 0.9 ～5.7 μmol/L for woman.Using Prodia reagent,the reference interval of TBIL was 9.5 ～ 35.7 μmol/L for man,and 6.8 ～ 28.9 μmol/L for woman,and the reference interval of DBIL was 1.3 ～ 7.0 μmol/L for man,and 1.0 ～ 6.6 μmol/L for woman.Conclusions The level of TBIL and DBIL in physical examination population was higher than the existing reference interval.It is necessary to modify the existing reference interval and establish reasonable reference interval for different regions and gender,respectively.

Objective To evaluate the role of angiocadiography(ACG)in the diagnosis and management of complex/complicated congenital heart disease(CHD).Methods A retrospective study of ACG findings in 360 cases with complex/complicated CHD was performed with a comparision to that of echocardiography(Echo)and related clinical examination.Results The present series of CHD cases included pulmonary atresia with ventricular septal defect in 75 cases,double outlet of right ventricle in 62 cases,Fallot's tetralogy in 60 cases,single ventricle in 52 cases,transposition of the great arteries in 42 cases,tricuspid valve atresia in 15 cases,coronary abnormality in 6 cases,total abnormal pulmonary venous connection in 5 cases,total endocardial cushion defect in 5 cases,persistent truncus arteriosus in 4 cases,pulmonary atresia with normal ventricular septum in 3 cases,other disorders in 7 cases,and postsurgical operation in 24 cases.ACG was superior to that of Echo in demonstrating the abnormalities of systemic,pulmonary,and coronary arteries and their branches of complex/complicated CHD as well as measuring the pressure of pulmonary artery,vein,and systemic-pulmonary collateral vessels.Conclusion In the diagnosis and differential diagnosis of knotty cases with complex and complicated CHD,particularly in the demonstration of full view of systemic,pulmonary,and coronary arterial branches and accurate measurement of pulmonary arterial pressure/resistance,and atrial,ventricular,and systemic arterial pressure,ACG(including DSA)still plays an important and irreplaceable role.

Objective To explore a new bio-dynamic differential equation to establish gene regulatory network based on the time-space of gene expression.Methods According to bio-dynamic competitive model and differential equation,a new time-space Lotka-Volterra differential equation was established and was applied to time-order expression data.Results The model was applied to set up the regulation network of yeast genes.The regulatory relation was found and compared with the experiment results.Conclusion The results from the new model were almost consistent with the real situation.So this model can remedy the shortage of other models.It's a new valuable differential equation model.

Objective To describe the relationship between ambient air pollutants(TSP,SO2,NOx) and the level of children’s lung function (FVC,FEV1,MMEF) in China. Methods The papers on ambient air pollution and children lung function published from 1985 to 2006 were collected and 11 of them were selected according to the following criteria: children aged 7-15; local air quality monitoring results were reported; strict quality control were taken when testing children lung function; the results were expressed by the average of measure. Results The selected papers included the results of 7 cities in China. Among them,the result of 6 cities showed that the levels of children lung function were significantly lower in the heavy air pollution areas compared with that in the light pollution areas. According to the papers,the average levels of ambient air TSP were in the range of 0.084 mg/m3-0.835 mg/m3,SO2(cSO2) were 0.013 mg/m3-0.929 mg/m3,NOx were 0.044 mg/m3-0.229 mg/m3,there was a significant negative correlation between the levels of TSP and SO2 and children FVC and FEV1,as well as the levels of NOx and children MMEF,the correlation coefficients were as follows,-0.797(t=-4.384,P=0.001) between TSP and FVC,-0.693(t=-4.190,P

OBJECTIVE:To discuss the way,approach and the effects of continuing education of pharmacists in hospital.METHODS:Multimedia and lectures were adopted as the mode of teaching medical courses and exam system was established as well.RESULTS:Continuing education made up for pharmacists'lack of medical knowledge to some degree,which laid a specialty foundation for pharmacists in the clinical service.CONCLUSIONS:The mode of launching continuing medical education for pharmacists is practicable,which can make up for the current lack of clinical pharmacy graduates from medicine academy.

Objective To investigate the effects of Genistein (GEN) acting on human lung adenocarcinoma A549 cells induced by LPS;To discuss its action of mechanism for improving injuries of lung. Methods The activity of cell treated with different concentrations of Genistein was detected by CCK-8 method and/or LPS intervention for 12 h. The expressions of inflammatory cytokines IL-1β, IL-6, and TNF-α induced by LPS were detected by RT-PCR. TUNEL was used to detect apoptosis, and Western blot was used to detect the changes of signal pathway. Results GEN (1, 5, 10μmol/L) alone had no effects on cell activity;LPS (1μg/mL) reduced cell viability significantly, while co-treated the A549 cells with GEN and LPS could reverse this condition in a concentration-dependent manner;RT-PCR results showed that LPS could significantly increase the level of gene expression of inflammatory factors, while GEN could inhibited this phenomenon in both concentration-and time-dependent manner;the results of TUNEL staining showed that GEN (10μmol/L) combined with LPS for 12 h could significantly decrease the apoptosis rate;the results of Western blot showed that GEN possibly inhibited the inflammation and apoptosis through inhibiting the phosphorylation of IκBα, p65 signaling pathways. Conclusion GEN has anti-inflammation and anti-apoptosis effects on A549 cells induced by LPS, so as to play a protective rate.