The factors influencing the integration of MOOC and information literacy education in academic libraries were divided into objective factor, subjective factor and social factor according to their connotation and significance. Certain measures for their integration were proposed, such as strengthening network construction, perfecting literacy education systems, and carrying out systemic training.Integration of MOOC and information literacy education in academic libraries can improve information service, promote wide application of MOOC and information literacy ed-ucation in academic libraries.

Thyroid microsomal antigen-antibody(TMAg-Ab)system plays an important role in the pathogenesis of autoimmune thyroid diseases.TMAb are involved in the complementmediated cytotoxicity and antibody-dependent cytotoxicity,resulting in thyroid follicle epithelial cell and basement membrane injury,followed by thyroiditis and hypothyroidism,and they may also cause hyperthyroidism through some unknown mechanisms.In recent years,indirect hemagglutination,radioimmunoassay and enzyme-inked immunosorbent assay have been used to detect TMAb in thyroid disease patients'sera,indicating the incidence as high as 90%.Measurements of T3,T4 and TSH alsoreveal that serum TMAb level is related with the variation of T3,T4 and TSH.It ispostulated that TMAg might be the lipoprotein on smooth endoplasmic reticulum ofthyroid follicle epithelial cell.Due to the difficulties to purify TMAg,its nature stillremains unclear.

The serum thyroid microsomal antibodies (TMAb) and thyroglobulin antibodies (TGAb) were measured in 103 normal persons and 183 patients with different thyroid diseases by enzyme-linked immunosorbent assay (ELISA). The serum T3 and T4 were also tested. The results showed that the incidence of these two autoantibodies were obviously increased in Hashimoto's thyroiditis, hyperthyroidism and hypothyroidism, and normal in simple goiter and thyroid adenoma. The TMAb and TGAb levels in subacute thyroiditis and thyroid cancer were moderately increased. There were also a negative correlation between TMAb and T3, T4, TGAb and T4 in Hashimoto's thyroiditis.

Adult ; Body Mass Index ; Child ; Humans ; Insulin Resistance ; Obesity ; complications ; Sleep Apnea, Obstructive ; etiology ; physiopathology

Chemotherapy, Adjuvant ; Humans ; Stomach Neoplasms ; drug therapy

Adult ; Brenner Tumor ; diagnosis ; pathology ; Female ; Humans ; Ovarian Neoplasms ; diagnosis ; pathology ; Ovary ; pathology ; surgery

Objective: To analyze the outcomes of surgical treatment of obstructive jaundice induced by biliary invasion in patients with gallbladder carcinoma. Methods: We retrospectively analyzed the clinical data of 48 patients with gallbladder cancer and biliary invasion-induced obstructive jaundice, who were treated in our hospital during January 2004 to December 2008. Results: Thirty-six patients who received surgical treatment had a median survival time of (17.39±3.98) months, and 12 patients received non-surgical treatment had a median survival time (3.75±0.51) months, with significant difference found between the two groups (P<0.01). Fifteen patients underwent radical resection, 7 underwent R1 resection, and 14 underwent R2 resection, with their median survival time being (30.93±7.42) months, (13.57±6.70) months, and (5.00±0.67) months, respectively; there were significant difference between the three groups (P<0.01). Conclusion: The prognosis of gallbladder cancer with obstructive jaundice is poor; surgical treatment can partly improve the prognosis of patients with obstructive jaundice-induced by gallbladder invasion. Radical curative resection, sometime with cholecystectomy, partial hepatectomy, or bile duct resection, should be performed for these patients.

Objective To explore the influence of family factors on physical activity behavior of central obesity patient.Methods A questionnaire investigation to 182 central obesity volunteers was carried out in a residential district of shanghai on April 2007.Results The percentage of the patients taking physical activities,at least one of whose family members participate in regular exercise,was 66.7%.It was significantly higher than that (43.6%) of other patients whose family members hardly ever participated in regular exercise any more(χ2=9.260,P=0.002).The percentage of patients taking physical activities,with highly family function,was 60.2%.It was significantly higher than that of the patients in moderately dysfunctional family (49.9%) and in severely dysfunctional family(35.5%)(χ2=6.448,P=0.04).The average APGAR score,Partnership score and Growth score of the patients in taking exercise group were 7.13±2.63,1.49±0.71 and 1.35±0.73. They were significantly higher than that of the patients in taking no exercise group (6.09±3.09,1.24±0.85 and 0.90±0.86) (t=2.095～3.845,P=0.000～0.038). While family size,family economic status and marital status showed no obvious effect on physical activity behavior of central obesity patients(χ2=0.027～1.709,P＞0.05).Conclusion Highly family function and at least one of the other family members taking regular exercise can promote activity of central obesity patient in daily life.

Objective:Study the effect about cone beam CT(CBCT) image guidance sytem to improve the positioning accuracy and reducing the set-up uncertainty in precise radiotherapy. Methods:Use CBCT system to scan head and neck tumors patients (30 cases) and chest tumor patients (40 cases), including head and neck tumor patients were scaned 90 times, chest tumor patients were scaned 113 times. Setup deviation statistics about anterior and posterior, head and feet, left and right direction. Results:The patients with head and neck cancer, the maximum error of anterior-posterior is 6mm, Three directions errors which greater than 3mm all less than 10%. Patients with chest tumor position error are in the head and foot direction, greater than 5 mm up to 21.51%. Before and after the direction of the error did not exceed 5mm. The left and right direction greater than 5 mm up to 4.53%. Conclusion:It greatly enhances the precision of radiotherapy, improved the curative effect of radiotherapy by using CBCT online image guidance system for the patient position correction. Compared with EPID, patients scaned with CBCT absorb smaller cumulative dose, the image resolution is higher, image matching is more accurate. But compared with the ordinary helical CT,the resolution and scanning range also need to improve.