1.Dynamic hip screw knife systemversus spiral blade anti-rotation intramedullary nail in the treatment of unstable intertrochanteric fractures
Yong LIN ; Xueping LIN ; Zhangtao RUAN
Chinese Journal of Tissue Engineering Research 2015;(26):4202-4207
BACKGROUND:Anti-rotation intramedulary nail fixation for proximal femoral fractures replaces the femoral bearing axis, moves towards body axis relative to hip screw and dynamic ankle screw, enhances the anti-fatigue strength at the fracture site, supports the anti-varus and prevents the rotation of the proximal fracture site, and is suitable for the treatment of unstable fracture. OBJECTIVE:To comparatively observe the effects of dynamic hip screw knife system and minimaly invasive spiral blade anti-rotation intramedulary nail in the repair of unstable intertrochanteric fractures. METHODS: A total of 82 cases of unstable intertrochanteric fractures, who were treated in the Department of Orthopedics, First People’s Hospital of Shunde from January 2012 to January 2014, were selected in this study. The patients were equaly and randomly divided into two groups: dynamic hip screw knife system group and minimaly invasive spiral blade anti-rotation intramedulary nail group. Repair index, fracture healing time and the incidence of complications were compared between the two groups. RESULTS AND CONCLUSION:Healing time and repair index were significantly better in the minimaly invasive spiral blade anti-rotation intramedulary nail group than in the dynamic hip screw knife system group (P < 0.05). Complications appeared in five patients from the minimaly invasive spiral blade anti-rotation intramedulary nail group, with the incidence rate of 12%, and in ten patients from the dynamic hip screw knife system group, with the incidence rate of 24%. The incidence of complications was significantly lower in the minimaly invasive spiral blade anti-rotation intramedulary nail group than in the dynamic hip screw knife system group (P < 0.05). These data suggest that for patients with unstable intertrochanteric fracture, minimaly invasive spiral blade anti-rotation intramedulary nail can decrease the incidence of complications, elevate the safety of the repair method, and promote the functional recovery.
2.Determination of Arsenic in Cosmetics With Graphite Furnace Atomic Absorption Spectrometry
Yuzhen LIN ; Guohong RUAN ; Honglin LIN
Journal of Environment and Health 1989;0(06):-
Objective To establish an analytical method to determine arsenic in cosmetics with graphite furnace atomic absorption spectrometry. Methods Arsenic in cosmetics was determined by graphite furnace atomic absorption spectrometry with citric acid as a matrix modifier. Results The detection limit was 0.03 ? g/ g, the related coefficient of the standard curve for the present method was 0.997-0.999, and relative standard deviation was 4.7%, rate of recovery was 92%-106%. Conclusion Graphite furnace atomic absorption spectrometry is sensitive, reliable, simple and rapid for determination of arsenic in cosmetics.
3.HMGB1 RNAi inhibits TGF-β1 induced epithelial-mesenchymal transition in A 549 cells
Lin CAI ; Zhiyan RUAN ; Jun XU
Basic & Clinical Medicine 2015;(2):183-186
Objective To investigate the role of HMGB 1 in epithelial-mesenchymal transition .Methods Specific siRNA of HMGB1 was designed and synthesized .Cultured typeⅡalveolar epithelial cell line-A549 cells were divided into 4 groups:1)control group, 2)model group induced by TGF-β1, 3)HMGB1 RNAi group, 4)RNAi negative con-trol group .Cellular morphology changes were observed by phase-contrast microscope .HMGB1 andα-SMA expression in A549 cells was detected by RT-PCR and Western blotting respectively .Results mRNA and protein expression of HMGB1 andα-SMA in TGF-β1 group increased significantly than that in control group (P<0.01).HMGB1,α-SMA mRNA and protein expression in siRNA-treated cells decreased significantly as compared with that in TGF -β1 group (P<0.01).Conclusions HMGB1 may be involved in the TGF-β1 induced EMT.
4.Leg lengthening for cosmetic heightening
Mo RUAN ; Yueqiu LIN ; Zhongying ZHOU
Chinese Journal of Medical Aesthetics and Cosmetology 2002;0(01):-
Objective To study the security and effectiveness of leg lengthening in increasing the height of short stature for cosmetic reasons. Methods The improved bone lengthening technique was used to 60 adult short stature volunteers to prolong bilateral lower legs. All data, including healing time of the distracted bone, operative complications, recovery of limb function and height increment, were recorded. Results In all cases, the height increment was 5 to 10 cm (mean 6.8cm). Bone lengthening rate was 19.6 %. The healing time of the distracted bone was 6 to 16 months (mean 8.2 months). There was no severe complication occurred. Follow up for 2 to 8 years showed that all cases returned to work or study with normal gaits and satisfied body figure. Previous psychologic obstacles were eliminated. Two years after bone healing, the ability for intense activities was regained. Conclusion Leg lengthening for cosmetic heightening is a safe and effective therapeutic approach.
5.Effect of pulsing magnetic field on osteogenesis in cosmetic limb lengthening
Mo RUAN ; Pei ZOU ; Yueqiu LIN
Chinese Journal of Medical Aesthetics and Cosmetology 2002;0(01):-
Objective To study the effect of pulsing magnetic field (PMF) on the osteogenesis of the distracted region in cosmetic limb lengthening, and to search for an effective therapeutic method for promoting the recovery of the cosmetic patient. Methods Thirty adult short stature volunteers for cosmetic heightening were randomly divided into PMF group and control group, 15 in each group. Magnetic stimulation was given to the PMF group on the day after operation. X-ray examination was taken on fixed interval, and lengthening index was used for bone healing evaluation. Results The height increase ranged from 5~9 cm, mean (6.6?1.2) cm, and the mean lengthening rate was 19.2 % : 5~8 cm (6.2?1.1) cm in the PMF group and 5.2~9 cm (6.8?1.6)cm in the control group ( P
6.Biomechanical study of Ni-Ti shape memory alloy stemless femoral prosthesis
Feng LIU ; Yueqiu LIN ; Mo RUAN
Orthopedic Journal of China 2006;0(02):-
[Objective]To evaluate the biomechanical features of Ni-Ti shape memory alloy stemless femoral prosthesis.[Method]Using CT(computer tomography) scanning photographs of adult femur,three-dimensional model of the femur was built by CAD(computer aided design) software.Based on the the structure of femoral model,shape memory alloy stemless femoral prosthesis was designed.Three-dimensional finite element model was created for the normal femur,Ni-Ti shape memory alloy stemless femoral prosthesis,and traditional stemmed hip prosthesis.Under static loads and walking loads,the Von Mises stress distributions of each model were analyzed and compared.[Result]The stress distribution of shape memory alloy stemless femoral prosthesis was not obviously different from normal femur,stemless femoral prosthesis's proximal femoral stress was close to that of normal femoral model but significantly higher than traditional stemmed hip prosthesis.Von Mises stress of memory alloy claws was distributed evenly,and the Max was only 13.23Mpa,there was no stress concentration.[Conclusion](1) Ni-Ti shape memory alloy stemless femoral prosthesis has great biomechanical properties,may reduce the stress-shieding effect of the proximal femur.The fixed method that use memory alloy claws can make prosthesis fixed firmly to the bone and reduce stress concentration.
7.POTENTIATING EFFECTS OF ROYAL JELLY ON IMMUNO LOGICAL FUNCTION IN MICE
Zhibin LIN ; Yibin ZHANG ; Yuan RUAN
Chinese Pharmacological Bulletin 1987;0(01):-
Royal jelly (2.5g/kg/d igX8d) increased the clearance rate of iv charcoal particles in normal mice, and completely antagonized the decrease of clearance rate caused by cortisone acetate. It also potentiated the delayed type hypersensitivity ( DTH ) reaction of footpad induced by SRBC in normal mice, and entirely antagonized the inhibition of DTH reaction caused by eye lophosphamide. Royal jelly (2.5 g/kg/d ig X 7 d ) had no marked influence on hemolysin formation in normal mice and immunosuppressed mice caused by eye lophosphamide.
8.Centralized Management of Medical Instrument
Lifen RUAN ; Xiaoqing LIN ; Peiying ZHAO
Chinese Journal of Nosocomiology 2005;0(11):-
OBJECTIVE To conduct the centralized management of the medical instrument in the supply room,and to assure the quality and validation of the clinical nursing and the patient safety. METHODS The cleaning and packing procedures of the instrument were standardized.The reusable instrument would be concentrated to clean,pack,and sterilize.To create a photograph management system,and use the photos to distinguish specialized instrument. RESULTS The instrument was reprocessed in the supply room instead of the clinical departments by the method of the centralized management of the instrument,which provided better instrument care and reprocessing. CONCLUSIONS The supply room conducts the centralized management of the medical instrument and enhances the quality of the instrument reprocessing.
9.The effects of lipoprotein(a) level in diabetic nephropathy on urinary albumin excretion rate
Xueling RUAN ; Hongchu LIN ; Henglian WU
Chinese Journal of Practical Internal Medicine 2001;0(05):-
0.05).But in the group EDN and CDN,Lp(a) was significantly higher as compared with the former two groups (P
10.Correlation between body composition and the components of metabolic syndrome in postmenopausal women
Jing JIN ; Xiangyan RUAN ; Lin HUA
Chinese Journal of Tissue Engineering Research 2010;14(2):360-364
OBJECTIVE: To learn the prevalence of abnormal components of metabolic syndrome in postmenopausal women, and to explore the optimal body composition indices to predict the abnormal components of metabolic syndrome in postmenopausal women. METHODS: A total of 181 participants were recruited from postmenopausal women who came to Beijing Obstetrics and Gynecology Hospital for health examination between July 2006 and August 2007. They were 41-60 years of age, and there were 1-9 years since menopause. Their clinical and biochemical parameters were measured, including body height, body weight, waist circumference, hip circumference, sagittal abdominal diameter, blood pressure, follicle stimulating hormone, luteinizing hormone, estradiol, triglyceride, high density lipoprotein-cholesterol, fasting,plasma glucose, fasting insulin and body fat. The prevalence of the abnormal components of metabolic syndrome in postmenopausal women was investigated. The correlations between body composition indices and the components of metabolic syndrome were analyzed by partial correlation analysis independent of age, years since postmenopause and the level of estradiol. The body composition indices to predict the abnormal components of metabolic syndrome in postmenopausal women were explored. RESULTS: ①The prevalence of central obesity (waist circumference ≥ 80 cm), hypertriglyceridemia (triglyceride ≥1.7 mmol/L), low high density lipoprotein-cholesterol (high density lipopretein-cholesterol < 1.29 mmol/L), hypertension (systolic pressure ≥ 130 mm Hg or diastolic pressure ≥ 85 mm Hg, 1 mm Hg=0.133 kPa) and high fasting glucose (fasting plasma glucose ≥ 5.6 mmol/L)was 48.1%, 31.5%, 16.6%, 38.7% and 50.3%, respectively. ②Through partial correlation analysis, body composition indices (body mass index, waist circumference, waist-hip ratio, sagittal abdominal diameter, and body fat) had a positive correlation with triglyceride, systolic pressure, diastolic pressure and fasting plasma glucose, while a negative correlation with high density lipoprotein-cholesterol, independent of age, years since postmenopause and the level of estradiol.③Body composition indices and critical value of them used to predict the abnormal components of metabolic syndrome in postmenopausal women were as follows: hypertriglyceridemia: body mass index ≥ 24.845 kg/m~2; low high density lipoprotein-cholesterol: sagittal abdominal diameter ≥ 18.85 cm; hypertension: body mass index ≥ 23.33 kg/m~2; high fasting glucose: sagittal abdominal diameter ≥ 18.10 cm or body fat ≥ 36.515%. CONCLUSION: Central obesity and high fasting glucose are the most common metabolic disorders in postmenopausal women. Obesity is an independent risk factor of metabolic syndrome for postmenopausal women. Body composition indices and their critical values to predict the abnormal components of metabolic syndrome in postmenopausal women are found.