1.Treatment of Infantile Cerebral Palsy by Scalp Acupuncture Combined with Point Injection in 48 Cases
Journal of Acupuncture and Tuina Science 2003;1(6):9-10
The author treated forty-eight cases of infantile cerebral palsy with scalp acupuncture and point injection. After two courses of treatment the infants made progress in different degrees. Eight cases were cured,sixteen cases were obviously improved, twenty-two cases were improved and two cases were unchanged. The total effective rate was 95.8%.
2.Progress on molecular genetics in atypical hemolytic uremic syndrome
International Journal of Pediatrics 2011;38(2):147-150
Atypical hemolytic uremic syndrome(aHUS) has recently been shown to be a rare disease of genetic predisposition, including genes of complement factor H(CFH), membrane cofactor protein(MCP, CD46)and complement factor Ⅰ(CFI), which are complement regulatory genes. Genes mutation is about 50%,involving the three genes mutation, including nonsense mutation, missen mutation, silent mutation, splice mutation and insertion mutation. Autosomal dominant inheritance and autosomal recessive inheritance have been reported, however, for autosomal dominant inheritance, the three genes mutations are incomplete penetrance.
3.Clinical analysis of mvcoplasma infection and female associated diseases
Chinese Journal of Postgraduates of Medicine 2012;35(9):16-17
ObjectiveTo study the pathogenicity of mycoplasma and damage on female's health.Methods The type of infection,symptoms and complications of 128 female patients of mycoplasma infection were counted.The correlation of the disease causing by mycoplasma and other diseases was summarized.Results Among of the 128 patients,there were 78 patients(60.94%) of Mycoplasma urealytium infection,22 patients (17.19%) of Mycoplasma hominis infection,18 patients (14.06%) of Mycoplasma genitalium infection,10 patients(7.81%) of Mycoplasma urealytium and Mycoplasma hominis mixed infection.The disease causing by mycoplasma and associated diseases including 66 patients (51.56% )of non-gonococcal urethritis,48 patients (37.50%) of mucopurulent cervicitis,32 patients (25.00%) of pelvic inflammatory disease,8 patients (6.25%) of bacterial vaginosis,38 patients (29.69%) of adverse consequences of pregnancy,8 patients(6.25%) ofdysgenesia.ConclusionsMycoplasma urealytium is the major cause of non-gonococcal urethritis,and abortion,stillbirth,premature delivery,early delivery,such as pregnancy-related adverse effects.Mycoplasma genitalium is correlated with pelvic inflammatory disease,mucopurulent cervicitis; Mycoplasma hominis is correlated with bacterial vaginosis; Mycoplasma genitalium and Mycoplasma hominis are likely to lead to tubal infertility.
4.Clinical study in acupressure time after abdominal injection of low-molecular-weight heparin calcium
Chinese Journal of Practical Nursing 2008;24(28):6-8
Objective To investigate the relation of acupressure time and incidence rate of sub-cutaneous hemorrhage after abdominal injection of low-molecular-weight beparin calcium.At the same time to seek the most appropriate acupressure time to reduce incidence rate and area of subcutaneous hemor-rhage. Methods Patients(60 cases)undergoing abdominal injection of low-molecular-weight heparin cal-cium from October 2005 to August 2006 were selected.Each patient received 16 times of injection.They were divided into 8 groups according to acupressure time,the acupressure time for each group was 3,4,5,6,7,8,9,10 minutes. Incidence rate and area of subcutaneous hemorrhage was observed. Results Lo-cal acupressure time was related to the incidence rate and area of subcutaneous hemorrhage,P<0.01. The incidence rate and area of subcutaneous hemorrhage was statistically different between acupressure time of 6 minutes and 7 minutes,P<0.01,while other adjacent groups had no statistical difference. Conclusions Local acupressure time of 7 minutes can effectively reduce incidence rate and area of subcutaneous hemor-rhage after abdominal injection of low-molecular-weight heparin calcium.
5.Heredity effect on cord blood Th1/Th2 cells
Journal of Chongqing Medical University 2007;0(07):-
Objective:To explore the effect of heredity on functional states of Thl/Th2 in cord blood mononuclear cells(CBMC)of neonates,whether their parents have anaphylactic disease. Methods:Cord blood was taken from 40 normal full term neonatals,who were divided into 20 ones with their parents having anaphylactic disease(AD group),and 20 not(control group).Collect blood plasma and cord blood mononuclear cells(CBMC)of neonates were separated,Blood plasma was collected and after stimulation with PHA,cell proliferation was detected by MTT method. IL-2,IL-4,IFN-r,and GM-CSF in supernatant were assayed by ELASA after CBMCs were cultured in vitro for 48h. Results:In AD group,as compared with control group:(1)The expression of IL-2,IL-4 and GM-CSF in blood plasma were higher than those of control group(P
6.Impact of cerebral hemodynamics and oxygen metabolism of dexmedetomidine on patients with intracranial aneurysm surgery
Clinical Medicine of China 2014;30(11):1121-1123
Objective To investigate the effects of cerebral hemodynamics and oxygen metabolism of dexmedetomidine on patients with intracranial aneurysm surgery.Methods Sixty-four patients with intracranial aneurysm surgery were collected and randomly divided into study group and control group (32 cases for each group).Patients in the study group before induction of anesthesia were given dexmedetomidine and patients in the control group were given saline but anesthesia.Mean arterial pressure (MAP),heart rate (HR),cerebral metabolic rate of oxygen(CMRO2) in different time points were observed and time in intubation and intracranial aneurysm clamp before anesthesia were rescored.Cerebral blood flow (CBF),intracranial pressure (ICP) were observed and the recovery situation.Results At the intubation,MAP and HR in the study group after 15 min of intubation,time in intracranial aneurysm clamp and extubation were significantly lower than those of the control group(P < 0.05).CMRO2 in study group at the intubation and intracranial aneurysm clamp were (34.2 ± 5.0) % and (27.1 ± 4.2),significantly higher than that of the control group ((33.9 ± 4.3) %,(26.5 ±3.6) %; P < 0.05).CBF in study group at the intubation and intracranial aneurysm clamp were (53.5 ±8.8) ml/(100 g · min) and (56.8 ±9.2) ml/(100 g · min),significantly lower than that of control group ((67.3±11.2) ml/(100 g· min),(67.3 ±11.2) ml) (100 g· min); P<0.05) ; The same trend was seen in terms of ICP.Spontaneous breathing recovery time and extubation time in study group were (7.35 ± 1.12) h and(12.98 ± 3.76),significantly earlier than those of the control group((9.27 ± 1.45) h and (14.89 ±4.88) h; t =10.92,9.23,P <0.01).Steward scores in study group was (5.12 ±0.33),significantly higher than control group ((3.98 ± 0.28) ; t =5.55,P < 0.05).Conclusion Dexmedetomidine can certainly keep hemodynamic stability in patients with intracranial aneurysm surgery,improve rate of cerebral oxygen uptake and recovery performance,which is worthy of clinical application and promotion.
7.Determination of Glycohyodeoxycholic Acid and Glycochenodeoxycholic Acid in Pulvis Fellis Suis by HPLC-ELSD
China Pharmacist 2017;20(8):1480-1482
Objective: To establish a method for the simultaneous determination of glycohyodeoxycholic acid and glycochenodeoxycholic acid in pulvis fellis suis by HPLC-ELSD.Methods: The analysis of methanol extract of pulvis fellis suis was performed on a Welch Ultimate Plus C 18 (250 mm× 4.6 mm ,5 μm)column, and the mobile phase consisted of acetonitrile and 0.1% formic acid (40∶60).The flow rate was 1.0 ml ·min-1.Alltech ELSD 2000ES was used as the detector, the drift tube temperature was 105℃ and the nitrogen flow rate was 2.5 L·min-1.Results: Glycohyodeoxycholic acid and glycochenodeoxycholic acid had good linear relationships within the range of 0.306-4.590 μg (r=0.999 5) and 0.280-4.194 μg (r=0.999 4), respectively.The average recovery was 99.23% with RSD of 2.0% and 100.37% with RSD of 1.8% (n =9), respectively.Conclusion: The method is accurate, sensitive and repeatable, which can be used for the quality control of pulvis fellis suis.
8.Clinical effect of amiodarone in the treatment of coronary heart disease in emergency tachyarrhythmia
Chinese Journal of Primary Medicine and Pharmacy 2014;(19):2961-2962
Objective To investigate the effect of amiodarone in the treatment of coronary heart disease in emergency tachyarrhythmia .Methods 156 cases of coronary heart disease in patients with tachyarrhythmias were randomly divided into the treatment group and control group ,78 cases in each group .The treatment group was given amiodarone,the control group was given conventional therapy .The clinical effect was compared between the two groups.Results The total effective rate,incidence rate of side effects in treatment group were 88.4%,3.8%,those in the control group were 71.8%,14.1%.The differences between the two groups were significant (χ2 =18.33, 13.91,P<0.05).In the treatment group,36 cases had atrial fibrillation,cardioversion 34 patients,the cardioversion rate was 94.4%,followed by premature ventricular contractions (90.6%).Conclusion Amiodarone in the treatment of coronary artery disease emergency tachyarrhythmia is safe and effective ,has fewer adverse reactions ,the best results for atrial fibrillation and ventricular premature beats ,it is worthy of clinical use .
9.Clinical selection of individualizd artificial liver support
Chinese Journal of Clinical Infectious Diseases 2017;10(2):113-118
Liver failure is characterized by hepatic encephalopathy, jaundice, hypo-coagulation and high mortality.Artificial liver support aims to temporarily replace hepatic function until liver function recover or bridge to liver transplantation.Individualized artificial liver support should be balanced and cover the following aspects: removing albumin bound toxins and/or water soluble toxins, eliminating inflammatory mediators and correcting blood coagulation disorders, in order to support metabolism and modulate immune function and to promote the regeneration of hepatocyte and reverse multiple organ failure that may lead to death of patients.Traditional non-biological artificial liver support can't meet individualized treatment.Recently developed hybrid blood purification model, such as albumin dialysis, fractionated plasma separation and adsorption (Prometheus system) and plasma diafiltration (PDF) have provided more and better choices for individualized artificial liver support.Based on the characteristics of pathophysiology and organ dysfunction of liver failure, the author has designed an alignment diagram of individualized artificial liver support for clinical selection.
10.Improvement of maintenance chronergy for medical instruments
Chinese Medical Equipment Journal 1993;0(05):-
After defining chronergy for medical instruments maintenance,this paper generalizes the importance of maintenance chronergy,and puts forward some specific methods for its improvement.