Objective To evaluate clinical application value of DWI and reservation of liver function in patients with chronic liver disease. Methods Thirty cases of healthy control group, and 60 case group with chronic liver disease,including both 30 chronic hepatitis B and 30 cirrhosis. liver function in case group was analysed by venous blood samples. Case groups were divided into three groups according to MELD score: ＜30 group in 27 cases, 30 to 36 group in 17 cases, ＞36 group in 16 cases. All cases underwent liver magnetic resonance DWI. Among the case group, 15 cases were followed-up twice of pre- and aftertreatment. DWI images were read, ADC values of liver parenchyma were measured and standardized with the cephalospinal fluid (CSF) at the same slice. Used SPSS 13.0 for windows to treat the data, group comparison of ADC values were treated by one-factor analysis of variance, interclass comparison each other by SNK method, comparison between pretherapy and post-treatment by paired-samples t test. Results Healthy liver parenchyma of the control group is homogeneous signal on DWI. ADC pseudo-color pictures showed green on the homogeneous areas. Slightly restricted area of chronic hepatitis B showed irregular scattered patchy in DWI images, 25 cases in right and left lobes, 5 cases only in right lobe of the liver. ADC pseudo-color pictures reaveled blue region in proliferation-constrained areas. Restricted areas of the liver parenchymal become more evident, also showed an irregular liver edge in 30 cases of cirrhosis. The standarized ADC average values were: the healthy group (0. 47 ±0. 02) × 10-3 mm2/s, chronic hepatitis B group (0. 37 ±0. 03) × 10-3 mm2/s, cirrhosis group (0. 36 ±0. 04) × 10-3 mm2/s( F =97.05,P ＜0. 05).The difference between healthy group and patients group was statistically significant (P ＜ 0. 05 ). No statistically significant difference between groups of chronic hepatitis B and liver cirrhosis ( P ＞ 0. 05 ).Average ADC values of MELD score among groups of ＜ 30, 30 to 36, ＞ 36 were ( 0. 38 ± 0. 02 ) ×10-3 mm2/s,(0.35 ±0.02) × 10-3 mm2/s, (0.32 ± 0.03) × 10-3 mm2/s respectively. There is a significant difference among the three groups (P ＜0. 05). After treatment, DWI of 15 patients with chronic liver disease showed reduction in restricted areas, and the average ADC value from pre-treatment (0. 33 ±0. 03) × 10-3 mm2/s increased to(0. 38 ±0. 03) × 10-3 mm2/s, MELD score from pre-treatment 36. 01 ±6. 00 reduced to 27. 83 ± 4. 86. Conclusion DWI of chronic liver disease showed patchy diffuse restricted areas; more severe of the liver cell damage was, more worse the liver function was and lower ADC values was. ADC values increased after effective treatment, liver function recoved and diffuse restricted areas of liver parenchyma reduced.

Objective To explore the diagnostic index of the obesity with dual energy X-ray absorptiometry(DEXA).Methods The total and local parameters(the fat composition of the arm,leg,trunk and total body) in obesity group (135 cases) and the control group(75 cases) were measured with DEXA scan.The fat composition and distribution of body in the obesity and the healthy subject in different age and sex were analysed.The diagnostic index of obesity and healthy persons determined by DEXA.Results There was no significant difference between DEXA and the platform scale to weigh all the subjects.The fat content of the arm,leg,trunk and total body in the control group and the obesity group were respectively got.The P_5(the lowest limit of 95% confidence interval of obesity fat percentage)value of the obesity male was 23(P_5=23),while the female was 29(P_5=29)).There was no significant difference between DEXA and the BMI method in the positive result of the obesity.The total body fat content in the obesity group was higher than that of the control group in each age and sex group.The fat content of the female was higher than that of the male regardless of obesity group or control group.Conclusion The obese cut off point is 23% in male and 29% in female in the total body fat content.

Objective To study the value in predicting the postoperative pulmonary function of the patient with quantitative MSCT.Methods 16-slice spiral CT scanning of lung was performed in 24 patients with pulmonary carcinoma before and after the operation during eupnea.Then the postoperative forced expiratory volume in one second(FEV1) and forced vital capacity(FVC)were calculated according to the preoperative lung capacity which was measured by quantitative MSCT,FEV1 and FVC which were measured by pulmonary functional test(PFT),then the results of FEV1 and FVC predicted by MSCT were compared with that two months later after operation.Results There was significant relativity in FEV1 and FVC between predicted by MSCT before operation and measured by PFT after operation ( P was 0.190 and 0.563 respectively).Conclusion Quantitative MSCT can predict the postoperative pulmonary function exactly,which provides dependable reference data for lung resection in the patients.with pulmonary carcinoma.

Objective To evaluate the applied value of MSCT lung volumes measurement in diagnosing chronic obstructive pulmonary disease(COPD).Methods 40 patients clinically diagnosed with COPD and 26 healthy volunteers as control group underwent MSCT chest CT scanning . The relevant indicators of lung volumes were measured and calculated in comparison with the indicators of clinical lung function . The accuracy and sensitivity of every indicator of lung volumes in forecasting and screening COPD by using ROC curve method were evaluated.Results There were significant differences between the control group and the COPD group in the full expiration volume(Vex),the full inspiration volume(Vin),Vex/Vin and the ratio of the change of lung volume(P

Objective To investigate clinical usefulness of intracranial lesions in pre-and post-operation by functional MRI with blood oxygen level dependent(BOLD)technique.Methods Common MRI and Motor hand area functional MRI examinations were performed in 45 patients (fMRI group)with intracranial lesions adjacent to the motor cortex before and after operation. As contrast group, 20 patients with occupying position lesions were made a routine MRI examination without fMRI before surgery. A 1.5 T signa super conducting system was employment (GE company ,America). Results The focal transactivation domain of cerebration was seen on fMRI in all cases of fMRI group. The cortical motor hand area shown displacement in 22 cases with abnormal size and shape and found not displacement in 23 cases. The distribution of transactivation domain was not changed in different disease . There was positive correlation between the distance from lesions to the domains and myodynamia in preoperation(r=0.553,P0.05). Our data indicated that there was negative correlation between the distance and the difference of myodynamia (r=-0.570,P

Objective To study the abnormal findings and metabolic alterations of the brain in chronic hepatic disease with MRI and 1H magnetic resonance spectroscopy (1H-MRS) for better understanding the clinical significance of pallidal hyperintensity and the role in the diagnosis and treatment of hepatic encephalopathy (HE) . Methods Brain MRI and 1H-MRS examination were performed in 50 patients with chronic hepatic disease and 20 healthy volunteers. The pallidus index (PI) was calculated and the height of resonance peaks of Glx was measured. The correlation between PI and Child/Pugh classification, and the association between blood ammonia and the spectroscopic alterations were studied. Pre-and post-therapeutic comparative study was also conducted in 5 cases with chronic HE. Results PI was gradually increased from healthy volunteers to patients with chronic hepatitis and liver cirrhosis (1.01?0.04, 1.06?0.09, and 1.18?0.09), and the differences in PI value among them were significant (F=22.294, P

0.05). Homogenous or inhomogenous high signal in aplastic anemia were detected with decreased T 1 value. Homogenous iso-intensity was revealed in acute pure red cell aplasia with normal T 1 value. Aplastic anemia and acute pure red cell aplasia had a homogenous signal on T 2WI, their T 1 value showed significant difference (P

Objective To evaluate the MRI in the diagnosis of aplastic anemia (AA) and MRI changes after therapy. Methods MR imaging of lumber spine in 16 patients with AA proved pathologically were performed on 0.5 T superconductive MR unit with T 1WI, T 2WI, and STIR, slice thick 5 mm, slice gap 1 mm, matrix 180?256. Thirty cases of normal volunteers were examined as control group. Lumber spines of the two groups were studied by observation of MRI findings, measurement of the T 1 relaxation value. In AA group, the percentage of the hypointense signal areas in the centrum was calculated. Results Three patterns were classified by MR appearance in lumber spine of our cases. MR findings of pattern 1 (2 cases) were hyperintense on T 1WI, isointense on T 2WI, and hypointense on STIR, and all two cases were acute aplastic anemia (AAA). In pattern 2 (7 cases), a few irregular hypointense signals appeared in the background of hyperintense signal on all 3 sequences, and 5 of them were AAA. Pattern 3 (7 cases) demonstrated mixed irregular shape of hyperintense and hypointense signals, all 7 cases were chronic aplastic anemia (CAA). The percentage of the area of hypointense signal in AAA was significantly smaller than that in CAA (t=30 00, P

Objective To evaluate the diagnostic value of MRI and X ray and to analyze MRI and X ray characteristics in Med anemia Methods MRI was performed in thoracic spine,lumbar spine, sacral spine,pelvis,and superior femurs in 15 patients with pathologically proved Med anemia with T 1WI and T 2WI Seven of them were examined on X ray Twenty volunteers were examined on MR as control group The authors analyzed the manifestations of MRI in the Med anemia, including abnormality of signal intensity of bone marrow,T 1 value,vertebral alteration of size and shaped, spinal cord compression due to epidural extramedullary haematopoiesis, and compared with the findings of bone on X ray Results In the control group, bone marrow showed an inhomogeneous iso signal intensity with band shaped, triangular or motley high signal intensity in the middle or back part of the vertebra, neck of the femur on T 1WI and a homogeneous iso signal intensity on T 2WI in the vertebra, pelvis, and superior femur All cases with Med anemia had low homogenous signal intensity in the bone marrow of the vertebra, pelvis and superior femur on T 1WI but had no alterations on T 2WI The spinal cord was constricted resulting from protruding crushed vertebra with bullet like shape in 4 cases The soft tissue masses, confirmed as extramedullary haematopoiesis by operation, were demonstrated in 4 cases Among 7 cases with X ray examinations, 2 cases showed normal on X ray but abnormal bone marrow on MRI, another 5 cases demonstrated bone alteration including osteoporosis, widening of striations, enlargement of ribs and vertebras T 1 value showed (897 4?75 43)ms in the Med anemia group and (401 5?28 1)ms in the control group with significant statistical difference ( P

Objective To evaluate the value of MRI in diagnosis of craniopharyngiomas. Methods MRI findings of 52 craniopharyngiomas were analyzed retrospectively and correlated with pathology.Results 37 cases of all 52 cases craniopharyngiomas were located on suprasellar. Craniopharyngioma fluid collections were found to be uniformly hyperintense on T 2-weighted images. However, on T 1-weighted images, the signal intensity of the fluid ranged from hypointense to hyperintense, reflecting the presence of pathological contents in these tumors. Conclusion MRI is an effective method in diagnosis craniopharyngioma due to its direct multiplanar capabilities and sensitive signal changes.