Purpose: To determine the histopathology of enucleated post-traumatic eyeballs and the most frequent indicators for enucleation Methods: All eyeballs enucleated with a clinical diagnosis of ocular injury were reviewed. The study period was from 1971 to 1996 Results: There were 198 eyeballs studied. Males were three times more involved than females. The most affected age group belonged to the third decade of life. Eyeball rupture with expulsive hemorrhage and loss of intraocular contents accounted for the most common indication for immediate enucleation. Endophthalmitis and panophthalmitis were the next common indications for early enucleation. The rest of the eyeballs were enucleated from 3 months to 43 years after injury. Histopathology revealed the presence of staphyloma, atropia bulbi, pthisis bulbi and glaucoma. Synechiae, cataract and keratitis were the outstanding features of the anterior segment pathology. Retinal detachment, choroidal hemorrhage and detachment were the most significant findings in the posterior segment Conclusions: The major indications from early enucleation in ocular trauma are eyeball rupture with expulsive hemorrhage and infectious processes. Staphyloma, pthisis bulbi and glaucoma may develop in later years leading to enucleation.
Human ; Aged ; Middle Aged ; Adult ; Young Adult ; Adolescent ; Child ; Child Preschool ; Infant ; EYE ENUCLEATION ; OPHTHALMOLOGIC SURGICAL PROCEDURE

Objective: To report various intraocular conditions that mimic retinoblastoma. Methods: A review was conducted of eyeballs enucleated for suspected retinoblastoma between 2003 and 2007, and referred for histopathological confirmation. The slides of cases not histopathologically consistent with the diagnosis of retinoblastoma were reexamined. Clinical records and results of neuroimaging studies were reviewed retrospectively Results: Of the 197 eyeballs examined, 182 (92%) proved to be retinoblastoma on histological exam, while 15 (8%) from 13 patients were pseudoretinoblastomas. The age of patients ranged from 4 months to 9 years, with a mean of 35.5 months. The etiologies of the pseudoretinoblastomas were as follows: persistent primary hyperplastic vitreous (PHPV) in 5 eyeballs (33%); retinal dysplasia in 3 (20%); Coats’disease, phthisis bulbi, and vitreous hemorrhage with retinal detachment in 2 (13%) each; and granulomatous endophthalmitis in 1 (8%). Conclusion The 8% erroneous diagnosis was lower than the published rates of 10 to 20%. The common etiologies of pseudoretinoblastoma were similar to those reported.
Retinoblastoma ; Retinal Telangiectasis ; Retinal Dysplasia