1.Applying of Bar Code Technology in Medical Reports Management
Journal of Medical Informatics 2009;30(8):29-30
The paper introduces the bar code technology applying in medical reports management with the combination experience of Taizhou hospital, including relevant equipments and applying methods, statistics mode for bar code medical records circulation: medical records recovery subsystem, circulation management subsystem, query and return subsystem, bar code production subsystem, etc, as well as noted issues during the operation.
2.Establishment of Central Sterilization Supply Department Green Pass Way:Thinking and Practice
Chinese Journal of Nosocomiology 2009;0(18):-
OBJECTIVE Discussing the central sterilization and supply department (CSSD) working model,to change CSSD serving concept and to improve clinical satisfaction degree for CSSD. METHODS Nurse in charge set forth an aim to establish CSSD green pass way in 2007. CSSD applied the meticulous administration,prolonged its serving time,assigned trained workers to deliver emergency articles,and prepared the individual packets to meet clinical special needs. RESULTS Clinical satisfaction degree was increased from 58.0% in 2005 to 95.1%in 2008,and complains were decreased from 15 times in 2005 to zero in 2008 (P
3.Research on Relativity between Irritable Intestine Syndrome (IIS) and Gastro-intestinal Hormones
Journal of Zhejiang Chinese Medical University 2007;0(01):-
Referring to relative documents,it reviews the developments on the relation between IIS and gastro-intestinal hormones(gastrin,gallbladder bile-syst contractin,active vessel intestinal peptide and article P),and sums up the relativity study on the relativity between different TCM types of IIS and gastro-intestinal hormones secretion level.
4.Enhancement of NADPH: quinone oxidoreductase 1 (NQO_1) gene expression and inhibition of cell proliferation induced by ?-tyrosol in human hepatoma SMMC-7721 cells
Chinese Journal of Pathophysiology 2000;0(08):-
AIM: To investigate whether ?-tyrosol could induce expression of DT-diaphorase (NQO 1) gene and inhibit proliferation of hepatoma cells and their relationship.METHODS: The DT-diaphorase activity, mRNA expression and cell proliferation were examined using direct measurement of DT-diaphorase from cells cultured in microtiter wells, semi-quantitative reverse transcription-PCR (RT-PCR) technique and crystal violet assay after treatment of SMMC-7721 cells with ?-tyrosol for 24 h. RESULTS: Treatment of SMMC-7721 cells with ?-tyrosol caused an increase in DT-diaphorase activity and DT-diaphorase mRNA expression in a dose-dependent manner. A statistically significant correlation between DT-diaphorase mRNA levels and enzyme activities was evident. In almost the same concentration range of 70 mg/L to 100 mg/L, ?-tyrosol resulted in a dose-dependent inhibition of cell proliferation which well inversely correlated with DT-diaphorase activity.CONCLUSION: ?-tyrosol can induce DT-diaphorase activity and enhance expression of its gene, which may contribute to antiproliferation of hepatoma cells caused by the same chemical.
5.Relationships between CA9 and recurrence in clear cell renal carcinoma:a prelimina-ry investigation
Military Medical Sciences 2014;(12):945-947
Objective To study the expression of carbonic anhydrase 9(CA9) in clear cell renal carcinoma(ccRCC), and the relationship between the expression and recurrence .Methods Paraffin-embedded tissues from 53 ccRCC cases were collected during the past 3 years,and immunohistochemistry was used to detect the expression of CA 9.Fifty-three cases were followed up to evaluate the disease-free survival ( DFS) and recurrence .Association of CA9 expression with recurrence was then analyzed .Results Localized RCC recurred in eleven cases , the median DFS was 10 months, the integral optical density ( IOD) of the recurrent cases was 230 879 .84 ±64 878 .72 while the IOD of the thirteen nonrecurrent cases was much higher,444 993.31 ±146 946.27(P<0.01).Conclusion There might be a positive correlation between the low expression of CA9 and the recurrence of ccRCC .CA9 may help predict the ccRCC patients ’ prognosis.
6.Effects of recombinant human interleukin-11 on the vaginal epithelium mitosis of estrone periodical mice and the expression of PCNA
Chinese Journal of Biochemical Pharmaceutics 2016;36(4):49-51
Objective To investigate the therapeutic effects of recombinant human interleukin-11 (rhIL-11) on the vaginal epithelium mitosis of estrone periodical mice and the exprssion of PCNA.Methods The vaginal epithelium mitosis of estrone periodical mice was used as the epidermis hyperplasia model, rhIL-11 action in regulating the epidermis hyperplasia was observed and the expression of PCNA was detected by immunohistochemistry.Results The rhIL-11 significantly inhibited the mitosis of mouse vaginal epithelium, decreased the expression of PCNA ( P <0.01).Conclusion The rhIL-11 has good efficacy in treating the epidermis hyperplasia of psoriasis by inhibiting the mitosis of epithelium and decreasing the expression of PCNA.
7.Evaluation of the use of domestic clopidogrel in patients undergoing percutaneous intervention with individualized dose
Handong WU ; Lijun JIN ; Bin ZHANG
Chinese Journal of Interventional Cardiology 1996;0(04):-
0.05).Conclusion The use of domestic clopidogrel in PCI patients with individualized dose is safe and effective which can further reduce bleeding complications.
8.Studies on the effect of ulinastatin on hippocampal neuron and MMP-9 expression after ischemia-reperfusion injury rats
Lijun CAO ; Zemeng ZHU ; Jin WANG
Chinese Journal of Biochemical Pharmaceutics 2017;37(3):41-43
Objective To investigate the effect of ulinastatin on hippocampal neuron and matrix metalloproteinase-9 ( MMP-9 ) expression after ischemia-reperfusion injury rats, to reveal the mechanism of protection on hippocampus of ulinastatin.Methods The focal ischemia reperfusion model was made by thread embolism of middle cerebra1 artery, and ulinastatin was used.The animals were killed at 24 h after reperfusion was started.The sections of the brains were processed with Nissl staining and by immunohistochemistry with antibody of MMP-9.Results Corrected optical density (COD) of MMP-9 expression was significantly decreased after administration of ulinastatin.Also ulinastatin can obviously protect the structure of hippocampal neuron.Conclusion Ulinastatin could protect pyramidal cells in CA1 region from damage of ischemia-reperfusion injury and increase the number of normal neurons.Inhibition on MMP-9 expression was involved in the mechanism.
9.Gastrointestinal Hormones and Oxygen Free Radicals in IBS Rabbits of Spleen Deficiency
Journal of Zhejiang Chinese Medical University 2006;0(05):-
[Objective] To observe the effect of Leweiyin of traditional Chinese compounds prescription on gastrointestinal hormones and oxygen free radicals in IBS rabbits of spleen deficiency,and to explore the possible mechanism for the treatment of IBS with spleen deficiency.[Methods] 36 two-month-old rabbits with white feather and black eyes(WHBE rabbit),half male and half female,were randomly divided into 6 groups:normal group,model group,Xiangsha Liujun pill group,Lizhu Changle group,low-dose Leweiyin-treated group,high-dose Leweiyin-treated group.Except the normal group,others were made into IBS model of spleen deficiency which was induced by damp heat stress and gavage with Fanxieye as well as method of either hunger or gorge.The drug groups were administered preventively from the medium-term of the model reproduction to the end of modeling.The rabbits of each group were observed.NO,NOS,MDA,SOD in serum and SP in colonic membrane were detected.[Results] NO,NOS,MDA in serum and SP in colonic membrane significantly more increased than the normal group(P
10.Retrospective study of 33 deaths of in-patients with percutaneous coronary intervention
Hongbin ZHU ; Lijun JIN ; Taiming DONG
Chinese Journal of Practical Internal Medicine 2000;0(11):-
Objective To discuss the reasons of death in the in-patients with percutaneous coronary intervention(PCI).Methods Retrospective analysis was done in 33 cases who died in or after the procedures among 3 252 in-patients with PCI.Results 4 patients died in procedures and the others died after procedures.The major reasons of death in order were:cardiogenic shock,ventricular fibrillation,acute left heart failure,multiple organ failure,heart rupture and acute renal failure.The in-hospital mortality rate was 1.01%.Conclusion The major reasons of death of patients with PCI are cardiogenic shock,ventricular fibrillation and acute left heart failure.Taking some measures will reduce the in-hospital mortality rate.