1.Association of the serum soluble intercellular adhesion molecule-1 and soluble vascular cell adhesion molecule-1 with metabolic syndrome and its components
Furong ZENG ; Jian DU ; Lijuan CUI
Chinese Journal of Diabetes 2008;16(3):144-146
Objective To study the association of the serum soluble intercellular adhesion molecule-1(SICAM-1) and soluble vascular cell adhesion molecule-1(SVCAM-1) with metabolic syndrome(MS) and its components. Methods The MS was defined by criteria of the international diabetes federation. The levels of SICAM-1 ,SVCAM-1,plasma glucose,insulin,lipids,uric acid, glycosylated haemoglobin A(1C), and blood viscosity were measured. Results The concentrations of SICAM-1 and SVCAM-1 were significantly higher in subjects with MS and its components than in those without them. The concentrations of SICAM-1 and SVCAM-1 were correlated positively with disorder number of BMI, WHR, SBP, DBP,FPG, 2 hour plasma glucose, triglyceride, uric acid, HbA1c, blood viscosity and HOMA-IR,and negatively with high density lipoprotein cholesterol. Conclusions The concentrations of SICAM-1 and SVCAM-1 rise with the increase of the number of MS components. Endothelial dysfunction might participate in the occurrence and development of MS.
2.Treatment of chronic idiopathic thrombocytopenic purpura in the elderly by integrated traditional and western medicine
Lijuan SHAN ; Lan QIN ; Xiaojun DU
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(08):-
Objective: To observe the clinical effect of integrated traditional and western medicine in treating chronic idiopathic thrombocytopenic purpura (CITP) elderly patients. Methods: Sixty patients were divided randomly into the treatment group (n=30) and the control group (n=30), the former was treated with danazol combining with prednisone and Chinese drugs, while the latter was treated with VCR. Results: The total effective rate of the treatment group was better than that of the control group, the difference between those two groups was significant (P
3.Intervention Effects on Quality of Life with Pulmonary Rehabilitation Evaluation on COPD Patients Using CAT Assessment Tool
Yuanyuan HUANG ; Lijuan DU ; Hongyan QU
World Science and Technology-Modernization of Traditional Chinese Medicine 2013;(3):595-598
This article was aimed to evaluate clinical efficacy of the pulmonary rehabilitation health education guidance mode. The CAT assessment tool was used for evaluation of stable chronic obstructive pulmonary disease (COPD) inpatients and outpatients in the Respiratory Department, Affiliated Hospital of Traditional Chinese Medicine of Xinjiang Medical University. A total of 80 stable COPD patients were randomized divided into the treatment group and control group. In the treatment group, stable COPD patients received pulmonary rehabilitation health education guidance. And then the quality of life was evaluated. The results showed that compared with the control group, after 48-week health education intervention, the CAT score and dyspnea index scale score of 40 patients in the treatment group were decreased with significant difference (P < 0.05). It was concluded that the guidance mode of pulmonary rehabilitation health education was conducive to improving the quality of life of pa-tients with COPD, decreasing the dyspnea index score, and improving exercise tolerance in patients to a certain extent. This pattern can be implemented in the optimization of future clinical practice and nursing.
4.Effect of Family Pulmonary Rehabilitation Exercise on the Number of Acute Exacerbation of COPD
Chunyan LIAO ; Fengsen LI ; Lijuan DU
World Science and Technology-Modernization of Traditional Chinese Medicine 2013;(3):581-585
This study was aimed to evaluate the number of acute exacerbation of chronic obstructive pulmonary disease (COPD) and quality of life with family pulmonary rehabilitation exercise. Randomized controlled method 584 was used in the study. The COPD patients in the stability drug treatment were divided into the treatment group and control group. The treatment group A was given health education and pulmonary rehabilitation training in the family. And the treatment group B was given health education and treatment of pulmonary rehabilitation training in the family with acupoint application therapy. Health education was given in the control group. Changes on the number of acute exacerbation of COPD and quality of life were observed. The intervention time was one year. The results showed that patients after one-year pulmonary rehabilitation exercise in the family, the acute exacerbation (AECOPD) times of treatment group A and group B were obviously decreased (P < 0.01) compared to pre-treatment. The OR value was (0.79, 2.02) and (0.59, 2.11), respectively. The quality of life of treatment group A and group B was obviously improved (P < 0.05). The OR value was (3.39, 10.11) and (4.23, 9.57), respectively. Compared to the control group, the quality of life in treatment group B was obviously improved (P < 0.05). The OR value was (0.59, 7.78). It was concluded that the pulmonary rehabilitation exercise in the family can decrease the number of AECOPD and improve the quality of life of patients, reduce the risk of COPD patients in the future. This method is worth popularizing in the clinical and community practice.
5.Study about serum levels of high sensitivity C-reactive protein in subjects with varying glucose tolerances and its correlation with insulin resistance.
Furong ZENG ; Jian DU ; Lijuan CUI
Chinese Journal of Practical Internal Medicine 2006;0(17):-
Objective To investigate the difference of serum high sensitivity C-reactive protein(hs-CRP)concentrations in subjects with various glucose tolerances,and to analyze the correlation with insulin resistance.Methods A total of 90 subjects,who came from the Medical Examination Center of the First Hospital Affiliated to China Medical University from Oct.2004 to Apr.2005,were divided into five groups according to oral glucose tolerance test(OGTT):normal glucose tolerance(NGT)group;impaired fasting glucose(IFG)group;impaired glucose tolerance(IGT)group;IFG and IGT(IGT/IFG)group;newly diagnosed,complication-free type 2 diabetes(T2DM)group.By using the ELISA methods,the concentration of serum high sensitivity C-reactive protein(hs-CRP)was measured in these subjects,and its correlation with homeostasis model assessment insulin resistance index(HOMA-IR)was andlysed.Results The concentration of hs-CRP was significantly higher in IFG,IFG/IGT,T2DM than in NGT.The concentration of hs-CRP was positively correlated with glucose metabolism index and insulin resistance index.Conclusion Our study demonstrates that inflammation already exists not only in T2DM patients but also in subjects with IFG.Inflammation might participate in the occurance and development of T2DM.
6.Validation on Method of Microbial Limit Test of Povidone Iodine Solution
Xingfa YE ; Yanyan DU ; Lijuan DONG
China Pharmacy 2005;0(16):-
OBJECTIVE:To establish a microbial limit test method for povidone iodine solution.METHODS:Validation on methodology of the microbial limit test of povidone iodine solution was performed using plating method(Ⅰ),culture agent dilution method(Ⅱ),membrane-filter procedure method(Ⅲ)and sodium thiosulfate neutralization in combination with membrane-filter procedure method(Ⅳ).RESULTS:The recovery rates of all of the test organisms in method Ⅰ and method Ⅱ approached zero,less than 70% in method Ⅲ but above 85% in method Ⅳ.The growth of the control bacteria was abnormal in method Ⅱand method Ⅲ,but normal in method Ⅳ.CONCLUSION:It is advisable to adopt the method Ⅳ for microbial limit test of povidone iodine solution.
7.Effect of simvastatin on NF-kappa B p65 expression in liver of insulin resistant rats
Lijuan CUI ; Jian DU ; Dan ZHU
Chinese Journal of Diabetes 2008;0(07):-
Objective To study the effect of simvastatin(SV) on NF-kappa B p65 expression in liver of insulin resistant rats. Methods Male Wistar rats were divided into two groups:basic chow(NC,n=15)or high-fat diet(HF,n=20)for 10 weeks feeding, then assessed by euglycemic-hyperinsulinemia clamp technique. Rats in HF group were treated with(HFS,n=5)and without (HFN,n=5) SV 10mgkg-1d-1 in gavage for 5 weeks.NF-kappa B p65 expressions were tested with Western blot. Results The glucose infusion rate (GIR) in HF group decreased significantly compared with NC group (P
8.Influence of nursing intervention on psychological state of transfusion patients in outpatient and e-mergency department
Liping ZHANG ; Lijuan ZHANG ; Qiuhuan DU ; Tiange LV
Chinese Journal of Practical Nursing 2009;25(21):1-2
ObjectiveTo discuss the influence of nursing intervention on psychological state of transfusion patients in outpatient and emergency department. MethodsSCL-90 questionnaires were used to investigate 600 transfusion patients in outpatient and emergency department to understand their psychological state. Psychological nursing was given to them before, during and after transfusion, SCL- 90 questionnaire was used again for investigation at the last day of transfusion,χ2 test was used to evaluate the results. ResultsAfter psychological care, the somatization, interpersonal relationships, anxiety, depres-sion, hostility and terrorism and other items significantly alleviated compared with those before interven-fion. ConclusionsTo grasp the patients' psychological state and give psychological care to them can ef-fectively reduce the adverse psychological reaction of patients, improve the quality of care and safety and promote the treatment and rehabilitation of diseases.
9.Asthma morbidity and "stasis" relational research
Hongxia MA ; Fengsen LI ; Lijuan DU ; Huifang LIU
International Journal of Traditional Chinese Medicine 2010;32(5):402-403
Methods Acute attack of asthma patients with 84 patients, divided into virtual Asthma Group, the other card-based group, another non-choice of 63 patients with asthma, as a control group. Detection of all selected in the peripheral blood TXA2; TPA, PAI; blood coagulation. Results ①asthma group and control group case-control study results: OR=2.950, 95% CI (1.504, 5.785) exposure risk of the disease as non-exposed group of 2.95 times. ②Asthma group and the control group between the various indicators of hemorheology, in addition to TPA (P>0.05) no significant difference. Ms indicators are significant differences (P<0.05), suggested that asthma in the blood change detection indicators relative to the control group have changed significantly. Conclusion ①"Stasis" and asthma-related, "Stasis" Asthma is a major cause of morbidity. ②From stasis treatment of asthma, Huoxue Huayu Prescription provide the basis for the treatment of asthma.
10.Effect of auricular-plaster therapy on non-incisional pain from postlaparoscopic surgery
Ping LIU ; Jianhong WANG ; Zhengying BAO ; Lijuan SHI ; Ningna DU
Modern Clinical Nursing 2014;(4):5-7
Objective To observe the effect of auricular-plaster therapy on non-incisional pain from post-laparoscopic surgery.Methods Sixty patients with non-incisional pains from laparoscopic surgery were divided into experimental group (n=30) and control group (n=30).The patients of control group after laparoscopic surgery were routinely given the oxygen inhalation for 6 hours and encouraged to do off-bed activity earlier.Besides the above-mentioned treatment,the patients of experimental group were additionally given auricular-plaster therapy.The patients of two groups were compared in terms of pain intensity and duration.Result The pain duration in the experimental group was significantly shorter and the pain density was significantly lower than that of the control group (bothP<0.05).Conclusion Auricular-plaster therapy can significantly reduce the duration and intensity of non-incisional pain from gynecological laparoscopy.