1.The Living of People Leading Continius Regetable Existence and Ethical Thinking
Chinese Medical Ethics 1994;0(06):-
The essay dissussed the living of people who lead a continious vegetable existence and ethical thinking on the therapeutic valve, social influence and medical behaviour of them.
2.Study on Determination of Total Isofraxidin in Ciwujia Tablets by HPLC
Chinese Traditional Patent Medicine 1992;0(02):-
Objective: To establish the determination method of total isofraxidin in Ciwujia Tablets. Methods: In this method phenomenex C 18 column was used, acetonitrile -0.05mol?L -1 potassium dihydrogen phosphate solution (15∶85) was used as a mobile phase. The detection wavelength was at 344nm.Results: The recovery of the added sample was 102.8% and RSD was 2.2%. Conclusion: This method is simple and the result is reliable.
3.Testing method for electromagnetic field induced by electrical potential therapy equipment
Chinese Medical Equipment Journal 2015;36(5):127-129
The testing conditions and devices in the standards of China and foreign countries were summarized. The testing method was analyzed for the electromagnetic field induced by electrical potential therapy equipment. The safety range was proposed for the electromagnetic field of the tester, and then the risk was reduced greatly to the patient.
4.The effect of embryo aspiration and fetal cardiac activity area injection in transvaginal pregnancy multi -fe-tal reduction
Chinese Journal of Primary Medicine and Pharmacy 2016;23(2):217-219
Objective To evaluate the safety and effect of embryo aspiration and fetal cardiac activity area injection of transvaginal pregnancy multi -fetal reduction for women with early pregnancy.Methods Retrospective a-nalysis of 120 cases with transvaginal early pregnancy multi -fetal reduction was conducted.The pregnancy outcome of the two ways was analyzed and evaluated.Results Among 120 cases,55 cases were treated with fetal cardiac activity area injection,65 cases were treated with embryo aspiration.Fetal cardiac activity area injection group:gestational age (48.7 ±9.1)d,postoperative infection abortion rate:12.7% (7 cases),rate of premature babies:5.5% (3 cases). Embryo aspiration group:gestational age (46.9 ±4.2)d,postoperative infection abortion rate:6.2% (4 cases),rate of premature babies:3.1% (2 cases),the difference between postoperative infection abortion rate was statistically sig-nificant (P =0.02).Virgiria Apgar score (P =0.41),neonatal weight(P =0.70),fetal malformation rate (P =0.24),neonatal move to NICU rate (P =0.83),the differences were not statistically significant.Conclusion During the early stage embryo aspiration is a safe method for the multi -fetus reduction,the pregnancy outcome is better than fetal cardiac activity area injection.
5.Fingerprints of Herba Ephedrae by HPLC
Chinese Traditional Patent Medicine 1992;0(02):-
AIM:To study the HPLC fingerprints and to establish a sensitive and specific method for controlling the quality of Herba Ephedrae. METHODS: HPLC method was set up,using CLCphenyl column(5 ?m 4.6 mm?150 mm) with gradient elution,the mobile phase was comprised of acetonitrile and phosphoric acid(0.1%),the UV detection wavelength was at 215 nm,with a flow rate of 1.0 mL/min. RESULTS: There were 17 common peaks in the fingerprints of Herba Ephedrae based on 10 habitats.Sum of peak areas was larger than 90% total area.The similarity was compared and the HPLC fingerprints was set up. CONCLUSION: The quality of Herba Ephedrae can be controlled effectively by HPLC fingerprints.
6.X-ray analysis of Herba Ephedrae by fourier fingerprint
Jihong FU ; Jianbin ZHANG ; Lijing ZHANG
Chinese Traditional Patent Medicine 1992;0(01):-
AIM: To develop a new identification of crude drug Herba Ephedrae. METHODS: Using the method of X-ray diffraction fourier fingerprint patterns for the analysis and calculation of 12 habitats of Herba Ephedrae. RESULTS: The standard X-ray diffraction fourier fingerprint pattern of Herba Ephedrae was obtained with 26 peaks. CONCLUSION: The identification and quality control of Herba Ephedrae can be accomplished with X-ray diffraction fourier fingerprint patterns analysis.
7.He Jia Treatment H-hypertension's Clinical Experience by Applying the Method of Buqi Zhuyu
Lijing ZHANG ; Yawen ZHANG ; Jia HE
Journal of Zhejiang Chinese Medical University 2016;40(3):170-172
Objective]The article summarizes the H-hypertension's clinical experience by professor He Jia. [Methods]From following professor He Jia clinical studies, summarize professor He Jia from different ages, the treatment by applying the method of tonifying qi by stasis H-hypertension qi deficiency blood stasis syndrome differentiation thinking and clinical experience, and for proven cases.[Result]The professor He Jia considers the method of Buqi Zhuyu as the basic therapeutic principle, with pathogenesis of qi deficiency and blood stasis in the collaterals. And also to make up for points and syndromes differentiation from youthes and older, in the young and middle-aged people and see blood stasis into collaterals, the treatment of blood stasis by the main,the old people see more Qi deficiency into the network, to make up for the deficiency of Qi.Her clinical medicine is characterized in paying equal attention to the Qi and blood, Buqi Zhuyu, using opportunely insect medicine,Soufeng Tongluo,using the mineral medicine, Ziyin Qianyang along with the disease change, with good effect.[Conclusion]Professor He Jia for H-hypertension treatment of qi deficiency blood stasis unique insights, obtains good effect, often with fellow mutual information.
8.Clinical Study on Qiankun Capsule for Treatment of Lung Cancer
Shuchen ZHANG ; Gui LI ; Lijing YANG ;
Journal of Traditional Chinese Medicine 1993;0(01):-
Objective:To observe clinical,therapeutic effect of Qiankun Capsule on lung cancer and to study on the mechanism.Methods:100 cases of lung cancer were randomly divided into Qiankun Capsule group(capsule group),chemotherapy group and chemotherapy plus capsule group(combination group).Their clinical symptoms,immune indexes,blood picture,life state(assessed with Karnofsky criteria),body weight,and expression of p53 protein and proliferating cell nuclear antigen(PCNA)were compared. Results:The total effective rate of 94.12% in the capsule group and 90.91% in the combination group were significantly higher than 57.58% in the chemotherapy group(P
9.Protective effect of emodin on rats with pulmonary fibrosis and its partial mechanisms
Lijing LIU ; Hong QIAN ; Ping ZHANG
Chinese Pharmacological Bulletin 2015;(2):266-272
Aim To observe the influence of emodin on bleomycin-induced pulmonary fibrosis in rats, and explore its protective mechanisms. Methods Sixty SD rats were randomly divided into normal control group, sham operation group, model group, low-dose inter-vention group, high-dose intervention group and pred-nisone group. Each group included 10 animals. Rats in the latter 4 groups were intratracheally administered with bleomycin to establish pulmonary fibrosis model. From the second day, rats in low-and high-dose inter-vention groups were intragastrically treated with 2 mL of 20 and 80 mg · kg-1 emodin, respectively. Predni-sone group were intragastrically administrated with 2 mL of 5 mg·kg-1 prednisone acetate. However, con-trol and model groups were treated with 2 mL of normal saline. All rats were sacrificed on day 28. Pulmonary tissues were then removed, and HE and Masson stai-ning were performed. The contents of hydroxyproline ( HYP ) , malondialdehyde ( MDA ) , superoxide dis-mutase ( SOD) , glutathione-peroxidase ( GSH-Px) and catalase (CAT) in pulmonary tissues were measured. Serum concentrations of tumor necrosis factor-α ( TNF-α) , interleukin ( IL )-6 and IL-17 were detected by enzyme linked immunosorbent assay ( ELISA ) . The expression of Kelch-like ECH-associated protein 1 ( Keap 1 ) , nuclear factor-erythroid 2-related factor 2 (Nrf2) and nuclear factor-κB (NF-κB) p65 in pulmo-nary tissues was analyzed using Western blot. Results The pulmonary inflammation and fibrosis in low-and high-dose intervention as well as prednisone groups was significantly improved when compared with model group ( P<0. 05 , 0. 01 ) . In comparison with normal control group or sham operation group, pulmonary HYP and MDA contents, Nrf2 and NF-κB p65 expression levels in the nucleus, and serum concentrations of TNF-α, IL-6 and IL-17 were increased ( P <0. 01 ) , but pulmonary SOD, GSH-Px and CAT contents and Keap 1 expression levels in the cytoplasm were de-creased ( P <0. 01 ) in model group. Upon treatment with low-and high-dose emodin or prednisone, pulmo-nary HYP and MDA contents, Keap 1 expression levels in the cytoplasm, NF-κB p65 expression levels in the nucleus , and serum concentrations of TNF-α, IL-6 and IL-17 were reduced while pulmonary SOD, GSH-Px and CAT contents and Nrf2 expression levels in the nu-cleus were enhanced as compared to model group ( P<0. 01 ) . The above indicators were significantly im-proved in high-dose intervention and prednisone groups compared with low-dose intervention group ( P <0. 05). Nevertheless, There was no significant differ-ence between high-dose intervention group and predni-sone group ( P >0. 05 ) . Conclusion Emodin may protect against rats with pulmonary fibrosis by enhan-cing antioxidative ability and inhibiting inflammatory response.
10.Syndrome of inappropriate anti-diuretic hormone in lung-cancer patients:six cases
Dandan ZHU ; Daming ZHOU ; Lijing ZHANG
Chinese Journal of Clinical Oncology 2014;46(4):259-261
Objective:To investigate the clinical characteristics, treatment, and evaluation of the prognosis of syndrome of inap-propriate anti-diuretic hormone (SIADH) in lung-cancer patients. Methods:We review the clinical data of six lung cancer cases, includ-ing four small cell lung cancer, one adenocarcinoma, and one squamous cell carcinoma, with SIADH complication. All six cases were treated in our hospital over the past three years. Results:Patients with various serum sodium levels were provided different therapeutic regimens. Symptoms of fatigue and nervous system disorders, plasma sodium, urine sodium, and plasma osmotic pressure were alleviat-ed. Conclusion:SIADH is a common complication of lung cancer, particularly in small lung cancer cases. Electrolyte disturbances indi-cate poor prognosis, high mortality rate, and delay in treatment because of clinical interest. After a final diagnosis has been made and ap-propriate treatment has been administered, clinical symptoms were relieved and blood sodium levels were quickly and significantly im-proved in these patients.