Some vasovagal syncope (WS) patients developed tachycardia during the head-up tilt test (HUTT), of which bradycardia is the most common. There are different in shape of ECG waves between HUTT negative patients and HUTT positive patients.The dysfunction of autonomic nerve system could be the main reason.It could be helpful in diagnosis and treatment of VVS to leant the ECG change and its predictive value of HUTT result, effect of treatment and prognosis.

Brain metastasis is a common and devastating consequence of disease progression in patients with lung cancer.Epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKI) may enhance radiosensitivity by reducing the cells in S phase,reducing angiogenesis of tumor cells,increasing irradiation apoptosis,inhibiting tumor cells proliferation by fractionated irradiation and reducing radiotherapy resistance.The clinical results of radiotherapy combined with EGFR-TKI (such as gefitinib) in treatment of brain metastasis from lung cancer showed higher response rate and longer survival.The toxicities during EGFR-TKI treatments were low,and could be controllable after symptomatic treatment.Administration of EGFR-TKI combined radiotherapy conferred minimum influence on radiotherapy.

Language learning strategy is one of the most important items in current college English syllabus,yet it hasn't been given enough attention to.Due to the features of medicine,it is of great importance and emergency to carry out language learning strategy training in medical colleges.The aim of this essay is to promote a new English teaching mode of strategy-based instruction.

Objective To study the inhibitory effect of berberine on human nasopharyngeal cancer cell line CNE-2 in vivo and in vitro. Methods CNE-2 cell proliferation was measured by MTT assay and cell cycle was analyzed by flow cytometry. Cell morphology was observed with transmission electron microscopy. The cell cycle relative protein was detected by Western blotting. DNA and protein syntheses were assessed by the cellular incorporation of ~ 3 H-TdR and ~ 3 H-Leu, respectively. Anti-tumor activity of berberine in the experimental transplantation tumor CNE-2 was evaluated by relative tumor growth ratio. Results Berberine inhibited CEN-2 cells growth in a time-and dose-dependent manner. MTT Assay showed that the IC_ 50 values of 48 and 72 h were (49.5?5.8) and (13.3?2.0) ?mol/L, respectively. Cell cycle analyses of 50.0 ?mol/L berberine-treated CNE-2 cells by flow cytometry showed the accumulation of cells in the G_2/M phase while 25.0 ?mol/L berberine treatments for 48 h induced apoptosis with the index of (48.9?10.4)%. The inhibition of CNE-2 cell growth by berberine was associated with suppression of cyclin B1, CDK1, and cdc25c proteins. After the treatment of berberine at dose of 30 mg/kg, the median tumor volume was 317.9 mm~3 which was much lower than that in control group (P

Objective To study the 5 years contraceptive efficacy of levonorgestrel intrauterine system (LNG-IUS) and the ovarian functions in amenorrhea women. Methods LNG-IUS and TCu 380A IUD were randomly inserted in 2 groups of women, 50 each. Women were followed annually for 5 years. Serum follicle stimulating hormone (FSH), luteinizing hormone (LH), prolactin (PRL), estradiol (E 2), and T levels in 14 women with amenorrhea, and endometrial biopsies were obtained in 9 cases. Results By the end of 5 years, there were 2 pregnancies in TCu 380A group, but none in LNG-IUS group; and 24 amenorrhea cases in LNG-IUS. The 5 year cumulative continuation rates were 24% for LNG-IUS and 78% for TCu 380A ( P