With the development of 3G/4G mobile communication technology and the rapid growing Internet use,a variety of multimedia and media contents will be consumed on the phone,which potentially gives the population more opportunities to interact with media.Traditional paperbased journals can increase their influences by cooperating with the new media,like Weibo,mobile website/app.In the next decade,traditional journals and new media will likely to grow interdependencies instead of one being replaced by the other.If journals can utilize the strength of the new media through mobile websites/app or Weibo etc.,they could better serve for translational medicine.

The knowledge economy development depends on knowledge and innovation.Prime Minister,Keqiang Li,proposed that the development of Internet + action plan in the government's report of the Twelfth National People's Congress third meeting of,which made the whole China's Businesses animate.In such rapid development situation in terms of big data,cloud computing,Internet +,and other modern technology,integrate Internet resources,transfer big data into required da ta after analysis,change the magazine service mode,then promote clinical science and technology magazine to make it more humane-oriented as well as satisfy the need of each reader.This study proposed certain ideas on the development of the Internet + and medical technology magazines.

The rapid development of Internet offers a new place for public opinion exchange,which have become part of the frontier in the contemporary social management studies.Internet not only helps to facilitate information exchange and expanding the knowledge horizon,but also provides a platform to express opinions for public.It is a new norm for the public to engage online opinion discussions in the age of wide Internet coverage and raising number of Internet users.Medical opinion on the Internet,as a new platform for opinion exchange,becomes an important channel of information dissemination.Positive media expression and information may help to create a healthier environment for the medical market and public relations.As a new topic in the field of medical studies,the analysis of opinions on medical services has gained importance among many medical intelligence agencies and journals.It may potentially help journals to understand the trend in public opinions and offers academics and technicians related up-to-date information.It is an innovative medical intelligence gathering and analysis method,and will have important implications.

Editorial ethical issues gained an increasing attention in this dynamic and diversity society.It is therefore necessary to examine the ethical principles,codes of conduct,responsibilities,and obligations involved in the editorial work for science and technology journals,in order to maintain a positive public image of the editors.

Academic Journals is an important carrier and source of the technology information. Establishing branding awareness is a critical to improvement of journals and a contemporary science and technology trend journal in science -technology field. Therefore, branding awareness is worthy to be emphasized.

Medical scientific journals play an important role in medical technology innovation and dissemination of scientific ideas.It is the main channel for medical academic communication,and also an important platform for translation of novel scientific ideas to clinical practice.Therefore,medical scientific journals needs to develop themselves to better serve the clinical practice,medical education and research,and to play a leading role in the innovation of information dissemination,to provide fast and convenient platform for medical communication,so as to accelerate the spread of medical technological achievements,and to promote the advancement of medical technology.

Intercellular adhesion molecules 1(ICAM-1) and vascular cell adhesion molecule 1(VCAM-1) play important roles in the inflammatory process of cerebral ischemic injury.The expression of ICAM-1 and VCAM-1 increases following cerebral ischemia;ICAM-1 and VCAM-1 promote ischemic inflammation through mediating leukocytes adhesion to the endothelial cells and eventually migration into brain tissue;the inhibition of the overexpression and effect of ICAM-1 and VCAM-1 can reduce cerebral ischemic injury.

Academic journal is the major channel for spreading science and technological advancement and it is also the main source of scientific information.We here introduce the experience of holding carefully designed lectures and seminars of Chinese Journal of Clinical Obstetrics and Gynecology.The topics were chosen to reflect the trend of the field and the features of the journal.The was proved an effective way to enhance the influence of the journal.

It is reported that zymogen granule membrane glycoprotein 2 (GP2 )and CUB and zona pellucida-like domain-containing protein 1 (CUZD1 )are the major autoantigens of autoantibodies against exocrine pancreas (PAB).GP2 is mainly expressed in the pancreatic acinar cell and M cells in small intestine follicle-associated epithelium,and CUZD1 is mainly expressed in uterus,ovary and pancreatic acinar cell.PAB is a relatively specific antibody for Crohn's disease (CD).The article reviewed the progress in study on autoantigens of PAB in CD.

Repeated calcium depletion and repletion of short term duration Ca2+ preconditioning CPC is hypothesized to protect the heart from lethal injury after exposing it to the Ca2+ paradox (Ca2+ PD). Hearts were preconditioned with five cycles of Ca2+ depletion (1 minute) and Ca2+ repletion (5 minutes). These hearts were then subjected to Ca2+ PD,ie,one cycle of Ca2+ depletion (ten minutes) and Ca2+ repletion (ten minutes). Hearts subjected to the Ca2+ PD underwent rapid and severely injury. CPC showed remarkable protection against the Ca2+ PD injury. Protein release from the perfusated heart was significantly reduced in CPC hearts compared with nopreconditioned Ca2+ PD hearts (0. 56 + 0. 10 and 1. 23 + 0. 10 mg/ml respectively ,P