1.Preparation and Quality Control of Jumazhitong Film
Baofeng YANG ; Yonglong HAN ; Xuehui GONG ; Huiping DONG ; Lihui LI
China Pharmacy 2005;0(22):-
OBJECTIVE:To prepare jumazhitong film and establish its quality control method.METHODS:The jumazhitong film former was made with PVOH-124 as the base,the content of the principal agent-dyclonine hydrochloride was determined by HPLC.RESULTS:Good linear relation was achieved when the detection concentration range of dyclonine hydrochloride was 40.8~408?g/ml(r=0.9 998),the average recovery was 101.3%(RSD=1.3%,n=6).CONCLUSION:The preparing technique of jumazhitong film former is simple,its quality is stable and the control method is feasible.
2.The value of digital mammography in detection of the negative palpable breast cancer in rural areas
Jianping XU ; Lihui GONG ; Lingmiao LU ; Fengting ZHUANG
Journal of Practical Radiology 2016;32(7):1040-1042
Objective To explore the value of digital mammography in diagnosis of the negative palpable breast cancer in rural ar-eas.Methods 6 754 women randomly selected among 13 700 female outpatients (range,30-83 years)in rural areas underwent dig-ital mammography no matter they had breast palpable masses or not.Results 72 cases with breast cancer were diagnosed by digital mammography (72/6 754).Clinical palpation showed positive in 59 cases (59/72)and negative in 13 cases (13/72)with aged 35-77 years.Among 13 cases with negative palpable breast cancer,6 cases were carcinomas in situ,3 cases were intraductal carcinomas,and 4 cases were infiltrating ductal carcinomas.Conclusion Digital mammography may help in detection of the negative palpable breast cancer in early time.
3.Reliability of flexural strength and subcritical crack growth of two kinds of zirconia ceramics
Xu GONG ; Xinyi ZHAO ; Chunbao ZHANG ; Shibao LI ; Lijuan SHEN ; Bing WU ; Lihui TANG ; Yulu WU
Journal of Practical Stomatology 2015;(5):611-614
Objective:To evaluate the reliability of flexural strength and subcritical crack growth(SCG)of WL and HT zirconia ce-ramics under cyclic loading.Methods:Bar-shaped speciments of WL(n =30)and HT(n =30)were fabricated and loaded in three-point bending and cyclically fatigued.The flexural strength and the number of cycles to fracture were obtained from three-point flexural test and cyclic fatigue test respectively.Data were examined using Weibull statistics.Pairs law was used to analysize the subcritical crack growth(SCG),the behavior of which was described in terms of crack velocity as a function of maximum stress intensity factor (KImax ).Results:The Weibull module(m)of WL and HT was 10.64 and 12.04,the stress corrosion cracking susceptive indexes(n) 23.71 and 32.87,the SCG 90% and 76.7%,the KImax 49.6% and 50.9% of its maximum stress intensity factor(KIC ),respectively. Conclusion:WL and HT produce pronounced SCG.The minimum fatigue crack growth rate of HT is lower than that of WL(νHT <νWL ).
4.Application of quasi-collective education in chronic renal failure dialysis patients before discharge
Lihui GONG ; Ying HU ; Zhaomin ZHANG ; Jing CHENG
Chinese Journal of Modern Nursing 2018;24(8):935-938
Objective To explore the effects of quasi-collective education in chronic renal failure dialysis patients before discharge. Methods A total of 94 cases of first hemodialysis patients in the First Affiliated Hospital of Harbin Medical University from April 2016 to March 2017 were selected as the research objects by convenience sampling method. According to the admission date, 45 patients admitted from April to September 2016 were assigned to control group, and 49 patients admitted from Octorber 2016 to March 2017 were assigned to observation group. Routine discharge health education was applied in the control group, while quasi-collective education was adopted in the observation group. The growth rate of body mass index (BMI), the incidence of complications, the average education time and patient satisfaction with education were compared between the two groups. Results On the 30th day of discharge, the growth rate of BMI of the observation group was lower than that of the control group, while the compliance was higher than that of the control group, and the differences were statistically significant (t=5.289, Z=4.566; P<0.01). The incidence of dialysis complications in the observation group was lower than that in the control group, and the average education time was higher than that in the control group. Patients' satisfaction with education in time consuming, freedom, autonomy and richness in the observation group were statistically significantly higher than those of the control group (P<0.01). Conclusions Quasi-collective education can significantly improve the discharge education effectiveness in chronic renal failure dialysis patients, so as to improve the treatment effect.
5.Rapid genetic diagnosis of patients with non-syndromic sensorineural hearing loss.
Wei ZHANG ; Shusheng GONG ; Lihui HUANG ; Bo LIU ; Liping ZHAO
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2011;25(13):593-596
OBJECTIVE:
To evaluate the feasibility of a rapid genetic diagnosis technique in molecular genetics study of hearing loss.
METHOD:
One hundred and ten subjects including 54 with moderate to profound non-syndromic sensorineural hearing loss were enrolled in this study. All with informed consents. Their peripheral blood samples were taken and tested using Hearing Loss Array Kit developed by Capital Bio. Nine hot mutation sites from 4 high risk genes were tested each.
RESULT:
The overall positive rate in this cohort was 50.9%, while the positive rate among 54 hearing loss cases was 59.3%. DNA sequence analysis showed 100% coincident with gene chip results.
CONCLUSION
This Hearing Loss Array Kit (gene chip) has a high positive detection ratio, its characteristics such as rapid high-flux sensitive and high specific make it possible and promising in future screening and diagnosis in patients with sensorineural hearing loss. Molecular genetic diagnosis also has a profound value in deafness prevention.
Child, Preschool
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Female
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Hearing Loss, Sensorineural
;
diagnosis
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genetics
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Humans
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Infant
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Male
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Molecular Diagnostic Techniques
;
methods
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Mutation
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Oligonucleotide Array Sequence Analysis
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Sequence Analysis, DNA
6.Fluoride release and recharge properties of six restorative materials
Yajie GUI ; Xinyi ZHAO ; Shibao LI ; Lihui TANG ; Xu GONG
Chinese Journal of Stomatology 2015;50(1):28-32
Objective To evaluate the F-releasing and recharging properties of six dental restorative materials.Methods Disc specimens 10 mm in diameter and 1 mm in thickness were prepared from 6 different dental restorative materials:Fuji Ⅶ [glass ionomer cement(GIC)],Fuji lⅡ LC(light-curing,GIC),Beautifil(giomer),Compoglass F(compomer),Charisma(composite) and Experimental Ⅰ (a fluoride releasing composite),with 10 discs for each material.Specimens were dipped in 5 ml deionized water and Frelease was detected using a fluoride-specific ion electrode every day from 1-7 days and every three days from 8-28 days.On day 28,specimens were exposed to a fluoride foam for 4 min and then dipped in water,then the F-concentration was detected every day for a week.The specimens were exposed to fluoride foam and fluoride release was detected repeatedly for three times.Results All materials presented the highest F release on the first day after dipping and the F-release sharply decreased after 24 h and slowly decreased after 3 days.On the first day,Fuji Ⅶ presented the highest F-release[(99.68± 15.21) μg· cm-2· d-1],followed by Fuji Ⅱ LC[(37.12±1.67) μg·cm-2·d-1],Experimental Ⅰ [(22.93±1.53) μg·cm-2·d-1],Compoglass F[(15.28±0.70) μg· cm-2· d-1],Beautifil[(2.40±0.52) μg· cm-2· d-1] and Charisma[(0.11±0.02) μg· cm-2· d-1].Within 28 days of dipping,both Fuji Ⅶ and Fuji Ⅱ LC released more F-than other materials did(P<0.05),followed by Compoglass F and Experimental Ⅰ,and Beautifil and Charisma released the least F-(P<0.01).After Fuptake,all materials released the highest F-on the first day and presented sharply decrease after 24 h and slowly decrease after 2 days.On the first day after F-uptake,Fuji Ⅶ presented the highest F-release (>40 μg· cm-2· d-1),much more than other materials(P<0.01),followed by Fuji Ⅱ LC(>25 μ.g· cm-2· d-1).Beautifil,Compoglass F and Experimental Ⅰ were close in F-release value(15-20 μg·cm-2· d-1),and Charisma showed the lowest F-release.Conclusions Two glass ionomers were shown to have highest capacity in F-release and uptake,followed by compomer and fluoride releasing composite.Composite demonstrated the lowest F-release and uptake and Giomer was comparable to composite in F-release and to compomer and fluoride releasing composite in F-uptake.