1.A STUDY OF THE MYOCARDIAL BRIDGES ON THE CORONARY ARTERIES IN THE CHINESE
Acta Anatomica Sinica 1953;0(01):-
1. The myocardial bridges on the coronaty arteries of 100 hearts were studied.These formations occur in 66.3?4.76% of the cases and were located as follows: (1) On the left coronary artery: 60.0?4.98% was found on the r. interventri-cularis ant.; 6.1?2.41% on the r. obliquus ventriculi sin.; 1.0?1.00% on the r. ter-minalis; 9.1?2.90% on the r. marginalis. (2) On the right coronary artery: 10.0?3.00% on the r. interventricularis post.;5.0?2.18% on the r. anteriores ventriculi dex.; 3.0?1.71% on the r. marginalis. (3) The rest: 3.1?1.76% on the v. cordis magna; 1.0?1.00% on the v. cordismedia. 2. Microscopic examination of 5 hearts showed that the myocardial bridge is a partof the superficial myocardial layer. 3. The result were discussed with those from other authors.
2.PRACTICE AND REFLECTIONOF TELEMEDICINE SERVICE DEVELOPED BY GENERAL HOSPITALSFOR PROMOTINGCOMMUNITY MEDICAL SERVICE REFORM
Modern Hospital 2015;(1):7-8,12
To improve the medical service quality in Community Medical Service by sharing practical experi-ence of telemedicine service developed by general hospitals, and expounding the significance and existing problems of telemedicine service developed by general hospitals for Community Medical Service.
3.Role of human leukocyte antigen-G small interference RNA in a choriocarcinoma cell line
Chinese Journal of Obstetrics and Gynecology 2001;0(08):-
Objective To study the role of human leukocyte antigen-G (HLA-G) in the carcinogenesis and development of choriocarcinoma. Methods We designed and synthesized a double strand small interference RNA (siRNA) of HLA-G, then transfected it into a HLA-G overexpressed choriocarcinoma cell line, JEG-3 by lipofectine; HLA-G mRNA level was detected by real time RT-PCR; HLA-G protein level was detected by western blot. The living cells of JEG-3 were counted under microscope after transfection by siRNA. Results Double strand siRNA of HLA-G effectively downregulated the mRNA level and the protein level of HLA-G. The mRNA levels by Ct value at different concentration (1.0, 2.5, 5.0 ?g/L) were 20.67?0.02, 21.37?0.03,21.43?0.02, respectively. They were significantly different compared with the control groups which were 20.33?0.01, 20.37?0.02,20.40?0.03, respectively ( P
4.A research on PGI_2 and TXA_2 for lung cancer patients and ones with lung cancer metastasis
Journal of Clinical Surgery 1999;0(05):-
Objective To explore the PGI 2 and TXA 2 for lung cancer patients and ones with lung cancer metastasis,in onder to provide nomal index for diagnosis and differential diagnosis in lung cancer metastasis.Methods To test plasma PGI 2 and TXA 2 by means of RIA in all cases.One group of patients who received non operative treatment:Six cases of patients with distant metastasis;Eight cases with hilus of long metastasis;Seven cases without metastasis.The other group of patients who received radical operation;Six cases of patients with distant metastasis;Seven cases with hilus of lung metastasis;Six cases without metastasis.Result The PGI 2/TXA 2 ratio of the patient whether distant metastasis or hilus of lung metastasis was obviously lower than that of the patients without metastasis( P
5.Detecting the levels of serum TPS、CYFRA21-1 and STNFR in patients with lung cancer and its clinical value.
Chinese Journal of Practical Internal Medicine 2001;0(06):-
Objective To investigate the diagnostic value of tissue polypeptide specific antigen (TPS),CYFRA21-1 and soluble tumor necrosis factor receptor (STNFR) in patients with lung cancer.Methods The serum levels of TPS,CYFRA21-1 and STNFR were determined by enzyme-linked immunosorbent assay (ELISA) in 72 patients with lung cancer,54 patients with benign diseases and 32 healthy adults.Results The levels of the 3 tumor markers in lung cancer group were significantly higher than those of the benign disease group and healthy control group,and the serum levels of this 3 tumor markers corresponding increased with the high TNM stage.The detectable rates of TPS (80.5%) and STNFR (81.9%) in serum of lung cancer were higher than CYFRA21-1(65.3%),and in TNM I group,the detectable rates of TPS (57.1%) and STNFR (57.2%) were higher than CYFRA21-1 (25.6%) too.Conclusion The TPS,CYFRA21-1 and STNFR can be used as a very useful and sensitive tumor marker in the diagnosis of lung cancer.The TPS and STNFR are better than CYFRA21-1 in clinical use.
6.Research and application of three-dimensional pelvic finite element models
Chinese Journal of Tissue Engineering Research 2007;0(35):-
Finite element is a common means to study pelvic biomechanics. This article introduces current methods to establish finite element model and application advances of the models in pelvis,and explores issues and future developing direction of pelvic finite element models.
7.Analysis of myelogram and clinical pathogenesis of 196 cases of patients with pancytopenia syndrom
International Journal of Laboratory Medicine 2015;(23):3398-3399,3402
Objective To explore the etiological spectrum of pancytopenia ,in order to improve the diagnostic accuracy . Methods Retrospectively analysed myelogram and clinical data of 196 cases of patients with pancytopenia syndrom .Results The dominant cause of pancytopenia syndrom in 196 cases of patients was hematological diseases (accounted for 68 .9% ) ,including acute leukemia (14 .8% ) ,myelodysplastic syndrome (12 .2% ) ,aplastic anemia(11 .2% ) and immune‐related pancytopenia(10 .2% );while non‐hematologic diseases accounted for 31 .1% ,including connective tissue diseases (10 .7% ) ,chronic liver disease(7 .2% ) and in‐fection(6 .2% ) .Conclusion Etiology of pancytopenia syndrom is complex ,which should be comprehensively analysed with closely contacting clinics ,in order to clarify the cause ,reduce misdiagnosis and missed diagnosis and improve the diagnostic accuracy .
8.Update on ketogenic diet therapies in epilepsy
Chinese Journal of Applied Clinical Pediatrics 2015;30(12):888-891
Although the ketogenic diet(KD) has originally been used to treat epilepsies,plenty of evidence about the efficacy to intractable epilepsy has not accumulated until recently.These epilepsy or epilepsy syndrome include:Dravet syndrome,Doose syndrome,infantile spasms,Angelman syndrome with epilepsy,tuberous sclerosis complex and focal cerebral dysplasia or other structural epilepsy.It is worth paying more attention to the efficacy of KD on cognition,language development and behavior problems.
9.Exploration on value of CD64 and procalcitonin in early diagnosis of pediatric bacterial diarrhea
International Journal of Laboratory Medicine 2015;(23):3413-3415
Objective To detect peripheral blood neutrophil CD64 and procalcitonin(PCT)in children with diarrhea ,and to ex‐plore significance for differential diagnosis of diarrhea in children .Methods A total of 180 cases of children with diarrhea treated in this hospital from July 2012 to May 2014 were selected as subjects ,and were classified into three groups :bacterial diarrhea group (n=60) ,viral diarrhea group(n=60)and non infectious diarrhea group(n=60) .The levels of peripheral blood neutrophil CD64 and PCT were determined in all three groups ,and the diagnostic values of CD64 index and PCT were evaluated .Results The peripheral blood neutrophil CD64 index and level of PCT in the bacterial diarrhea group were significantly higher than those in the viral diar‐rhea group and non infectious diarrhea group ,and the positive rates of CD64 index and PCT in the bacterial diarrhea group were sig‐nificantly higher than those in the viral diarrhea group and non infectious diarrhea group ,all had statistically significant differences (P<0 .05) .The specificity and positive predictive value of CD 64 index in diagnosing bacterial diarrhea were significantly higher than those of PCT ,both had statistically significant differences (P<0 .05) .The relative analysis showed that the CD64 index was positively correlated with level of PCT (r=0 .865 ,P<0 .05) .Conclusion The CD64 index and PCT level of children with bacterial diarrhea increase significantly ,which indicates that the detection of CD64 index and PCT have significant clinical value in early diag‐nosis of bacterial diarrhea .
10.Regulation of endometrial stromal cells through the Wnt/beta-catenin signaling pathway
Chinese Journal of Tissue Engineering Research 2016;20(7):1013-1018
BACKGROUND:Increasing number of genes and signaling pathways are involved in regulating stem cels periodicaly, and wherein Wnt/β-catenin signaling pathway is an important pathway of stem cels.
OBJECTIVE:To investigate the effects of Wnt/β-catenin signal pathway on mouse endometrial stromal cels.
METHODS:After injection of Wnt/β-catenin pathway inhibitor or activator, endometrial tissues from Balb/c mice were obtained, some of which were used for detection of invasion of endometrial stromal cels and western blot detection, and the rest of which were used for preparing animal models of endometriosis folowed by immunohistochemical detection.
RESULTS AND CONCLUSION:The expression of β-catenin and GSK3β proteins was significantly higher in the activator group than the inhibitor group (P < 0.05). The number of transmembrane cels was significantly higher in the activator group than the inhibitor and control groups (P < 0.05). Immunohistochemical findings showed positive expression of E-cadherin in ectopic endometrial tissues of the inhibitory group, and strongly positive expression of vascular endothelial growth factor in ectopic endometrial tissues of the activator group. These findings indicate that Wnt/β-catenin signaling pathway may cause endometriosis by strengthening ectopic endometrial implantation, invasion and metastasis.