1.Clinical Observation on Combined Use of Urapidil Hydrochloride(Lixiding)and Dobutamine in Treatment of Severe Acute Congestive Heart Failure
Xiaopeng JIA ; Lianyu SHEN ; Guoding ZOU
China Pharmacy 2001;0(07):-
OBJECTIVE:To observe the therapeutic effects of Lixiding(LXD)plus dobutamine(DBT)on severe acute congestive heart failure.METHODS:A total of40patients,including25patients with coronary heart disease,10hypertensive cardiopathy and5ectatic myocardiopathy,were enrolled in this study.Before and after combined use of LXD and DBT,the SBP,DBP,HR,CI,PCWP,TPR and LVEF were measured and the data obtained were detected with t test.RESULTS:After use of drugs,the SBP,DBP,HR,PCWP and TPR significantly decreased in comparison with those before medication(P
2.Qingrehuashi Herbal Formula combined with high intensity focused ultrasound for treating advanced pancreatic cancer
Kun WANG ; Huifeng GAO ; Zhiqiang MENG ; Zhen CHEN ; Junhua LIN ; Peng WANG ; Lanyun FENG ; Yehua SHEN ; Lianyu CHEN ; Weidong SHI ; Luming LIU
Chongqing Medicine 2013;(27):3231-3233
Objective To evaluate the clinical efficacy of Qingrehuashi herbal formula combined with high intensity focused ul-trasound(HIFU ) in the treatment of advanced pancreatic cancer .Methods 86 patients with pancreatic cancer (22 case of III stage and 64 case of IV stage) were included in this study .18 cases were performed the HIFU therapy for 2-3 times .Other 68 cases re-ceived once HIFU therapy ,among 53 cases of liver metastasis ,8 cases were simultaneously conducted HIFU ablation therapy on liv-er metastasis .The patients were given Chinese medicines dominated by Qingrehuashi before and after HIFU therapy and during fol-low up period .Results The single evaluation on HIFU irradiation cases after 1 month:complete remision(CR) in 0 case ,partial re-mission(PR) in 8 cases(9 .3% ) ,stable disease(SD in 64 cases(74 .4% ) and progress disease(PD) in 14 cases(16 .3% ) .The median survival rate of 1 year and half a year was 52 .0% and 11 .4% .Among 73 cases of increased CA199 before treatment ,CA199 after treatment was decreased in 12 cases .Among 36 cases of increased CA242 before treatment ,CA242 after treatment was decreased in 15 cases .The effective rate of analgesic relief in all the cases was 70 .9% (62/86) .Conclusion The integrated therapy of Qingre-huashi herbal formula and HIFU is an effective method for treating advanced pancreatic cancer .