Objective To investigate the change and clinical application value of plasma D‐dimer in acute cerebral hemorrhage . Methods The plasma D‐dimer level was detected in 78 individuals of healthy physical examination(healthy control group) and 82 patients with acute cerebral hemorrhage .Results The plasma D‐dimer levels at admission(0 h) had no statistical difference among various groups(P> 0 .05) ;the D‐dimer level at 24 ,48 ,72 h in the small cerebral hemorrhage group was significantly higher than that in the healthy control group(P< 0 .05) ;the D‐dimer level in the massive cerebral hemorrhage group was significantly higher than that in the small cerebral hemorrhage group(P< 0 .05) ;the D‐dimer level in the small cerebral hemorrhage group reached the peak at 24 h ,while which in the massive cerebral hemorrhage group reached the peak at 48 h and was positively correlated with the intracranial hemorrhage volume(r= 0 .914 ,P= 0 .000 < 0 .05) .Conclusion The plasma D‐dimer level in the patients with acute cer‐ebral hemorrhage is obviously increased and shows the increasing trend with the intracranial hemorrhage volume increase ;the more the intracranial hemorrhage volume ,the longer the persistence time of high D‐dimer level .Therefore detecting plasma D‐dimer level has an important significance for monitoring the condition in the patients with acute cerebral hemorrhage .

Objective To observe the clinical efficacy and toxicity of intraperitoneal chemotherapy combined with intravenous chemotherapy in treatment of cervical cancer.Methods The experimental group of 40 patients received systemic chemotherapy of docetaxel and cisplatin combined abdominal intraperitoneal high-frequency hyperthermia in the control group,40 patients received docetaxel plus cisplatin chemotherapy,The efficacy and toxicity were observed.Results The complete remission rate of observotion group was 82.5％,significantly higher than 62.5％ in control group.Effective rate in observation group was 92.5％ and also significantly higher than 75.0％ in control gronp.After 6 cycles of chemotherapy,the improvement of the experimental group was 85.0％ higher than 57.5 ％ in control gronp.The differemles between the two groups was statistically significant(P ＜ 0.05); the main side effects during chemotherapy are gastrointestinal reactions,since the cells decreased,hair loss,the difference was not statistically significant(P ＞0.05).Conclusion The chemotherapy of docetaxel and cisplatin intraperitoneal chemotherapy can significantly improve the treatment of cervical cancer,without increasing side effects.