1.External application of Chinese medicine on acupoints in prevention and cure of bronchial asthma in children
Xinan SONG ; Lianwen MA ; Yiqiang LANG
International Journal of Traditional Chinese Medicine 2011;33(7):584-586
Objective To observe the therapeutic of Xiaochuanling ointment applied on acupoints combined with internal use of Yupingfeng pellets in the prevention and cure of bronchial asthma in children.Methods 80 children diagnosed of bronchial asthma were randomly recruited into a control group and a treatment group, 40 patients in each group. Patients in treatment group were treated with Xiaochuanling ointment applied on acupoints combined with internal use of Yupingfeng pellets. No treatment was used in the control group in relieving period, except observation and follow-up visit were performed. Observe the frequency,degree of asthma before and after treatment in both groups, along with the level variation of IgA, IgG, IgE and Eosnophils (EOS). Results After treatment, the average disease grade in treatment group was 1.82S with serum IgA (1.32±0.56) g/L, IgG (12.48± 1.85) g/L, IgE (257.06± 194.04) g/L, EOS (128.56±76.86) ×106/L and frequency of asthma (7.22 ±2.01). Compared with the control group and the treatment group before the treatment, there were statistical differences (P<0.01, P<0.05). Conclusion The effect of external application of Chinese medicine on acupoints in prevention and cure of bronchial asthma in children is especially remarkable.
2.Effects of rosuvastatin on endothdial function during myocardial ischemia-reperfusion injury in rabbits
Jianqun MA ; Lei ZHANG ; Lianwen WANG ; Yuqun ZHU ; Changyuan ZHANG
Chinese Journal of Emergency Medicine 2009;18(5):508-511
Objective To study the change of endothelial function during myocardial ischemia-reperfusion injury in rabbits and the effect of Rasuvastatin. Method Sixteen New Zealand rabbits were randomLy divided into two groups: ischemia/reporfusian injury group (control group) and Resuvastatin group(drug group). The myocar-dial ischemia-reperfusion model was established by occlusion of left anterior descending coronary artery for 40 min-utes evidenced by the elevation of the ST segment≥0.2 my on ECG waveform, and after release of ooclusion, the ST segment of ECG retttmed to 1/2 or more of the normal wavefonn, which was the evidence of successful reperfu-sion. The rabbit serum nitric oxide (NO) and plasma endothelia-1 (ET-1) content were assayed before occlusion, 40 minutes, 60 minutes and 180 minutes after reperfusion. SPSS11.5 software was used for ANOVA(Repested Measurement designs). P<0.05 was considered as statistically significant. Results There were no significant differences in serum NO and plasma ET-1 between two groups bsfore isehemia, but 40 minutes, 60 minutes and 180 minutes after reperfusion, the levels of serum NO in drug group were higher than those in control group [(82.000±13.825), (63.375±17.541), (50.250±18.987)μmol/L vs. (63.125±18.962), (43.500± 16.518), (29.625±14.162) μmol/L, P<0.05], and the levels of plasma ET-1 content in drug group were lower than those in the control group [(282.541±38.928), (315.152±55.263), (377.795±60.427) pg/mL vs. (331.785±35.341),(375.914±5.204),(459.829±70.110) pg/mL, P<0.05]. Conclusions By the means of increasing serum NO and decreasing plasma ET-1, rosuvastatin can improve the endothelial function in rabbits with isehemia-reperfusion injury.